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Prehab before liver transplant: a new hope for frail patients?

NCT ID NCT05237583

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a structured program combining exercise, nutritional advice, and psychological support is safe and doable for frail adults with cirrhosis waiting for a liver transplant. Twenty-five participants were enrolled to see if they could stick with the program and if it improved their frailty and nutrition. The goal was to help patients be stronger going into surgery, but the study was small and focused on feasibility, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Feb 2022

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age above 18 years * Diagnosis of cirrhosis, based on a combination of clinical, laboratory, imaging, or histology * Active on the liver transplant waiting list of the MUHC Exclusion Criteria: * Biological Model for End Stage Liver Disease \>20 * Hepatic decompensation within the last month * High risk varices not on primary or secondary prevention * Recurrent large volume paracentesis * Persistent hepatic encephalopathy * Platelets \<20,000/µL, or hemoglobin \<80g/L * Altered hemodynamics * Significant heart disease * Awaiting combined organ transplantation * Awaiting repeat liver transplantation * Condition limiting mobilization and/or exercise, or recurrent falls

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis Frailty Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McGill University Health Centre

    Montreal, Quebec, H3G1A4, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.