FRAILTY

This study tests a 24-week home exercise program for adults aged 60 and older who are frail or pre-frail. The program uses caregiver support and digital games to help participants exercise safely at home. Researchers will check if the program is practical and improves physical st…

This study tests whether a volunteer-led lifestyle program, supported by a digital tool, can improve muscle mass, strength, and mobility in older adults (60+) who have or are at risk for sarcopenia (age-related muscle loss). The program includes exercise and nutrition guidance de…

This study tests whether a program combining physical exercises with mental tasks can improve strength, balance, and thinking in frail adults over 65. About 220 participants will either join the program or receive standard care. The goal is to see if this approach can reduce frai…

This study tests whether a procedure that closes off a small heart pouch (left atrial appendage occlusion) combined with a heart-rhythm correction (catheter ablation) is safer and more effective than ablation plus daily blood thinners for frail patients aged 75 and older with atr…

This study tests whether a digital prehabilitation app (HEAL-ME) combined with creatine and whey protein supplements can help maintain muscle health and reduce frailty in 100 adults with cirrhosis. Participants will use the app and take supplements for at least 3 months. The goal…

This study tests whether a smartphone app that guides patients through exercises, nutrition tracking, and mood check-ins before cancer surgery can improve their physical function and reduce anxiety. Sixty adults scheduled for elective cancer surgery will either use the app or rec…

This study tests whether a program run by nursing and sports science students can help older adults in nursing homes become less frail. Frailty means increased weakness and slower movement, which raises the risk of falls and disability. The program includes supervised physical ac…

This study tests whether a 10-week program combining strength training with muscle relaxation exercises can reduce frailty, anxiety, and caregiver burden in people caring for a loved one with Alzheimer's. Researchers will compare this combined approach to relaxation alone in 62 i…

This pilot study will test whether combining physical exercises with non-immersive virtual reality can improve balance, thinking skills, and daily activities in adults aged 65 and older. Sixty participants will be split into three groups: one doing combined exercise and VR, one d…

This pilot study will test a 12-week telehealth program for frail adults aged 65 and older who have just left the hospital. Participants will receive weekly coaching sessions and use activity sensors to track their progress. The goal is to see if the program improves physical fit…

This study tests whether an 8-week tele-rehabilitation program can improve muscle mass, reduce frailty, and enhance quality of life in adults with cystic fibrosis. Participants will do supervised exercise sessions at home via video calls three times a week. The goal is to see if …

This study will test whether a virtual reality exercise program (PABLO) is better than standard physiotherapy (Otago) at improving balance and reducing falls in adults aged 45 and older who have fallen before or have balance issues. About 80 participants will do 12 weeks of super…

This study tests a home strengthening program for adults aged 65 and older who have sarcopenia (muscle loss) or frailty. Participants use a Bluetooth-connected resistance band and app that gives real-time feedback, while a doctor monitors progress remotely. The goal is to see if …

This study looks at whether two different exercise programs can improve physical function, balance, and mental well-being in older adults aged 60 and over living in Angola. A total of 350 participants will be randomly assigned to either a multicomponent exercise program or a simp…

This study looks at how frailty affects the quality of life in women aged 60 and older who are newly diagnosed with breast cancer. Researchers will measure changes in well-being and frailty over six months. The goal is to help doctors tailor treatments that focus on what matters …

This study looks at whether a kidney transplant-specific check-up for older adults (aged 60+) with advanced kidney disease can help doctors make better decisions about who is suitable for a transplant. About 50 participants will either receive this extra assessment plus usual car…

This study will follow 645 older adults (65+) who have had a heart attack to see how frailty influences treatment choices and recovery. Researchers want to know if adding a frailty check to standard risk tools better predicts who will have serious heart problems or die within 30 …

This study looks at 100 elderly patients with hip fractures to see if quick, easy tests like ultrasound muscle measurements, handgrip strength, and routine blood work can predict frailty. Frailty affects recovery after surgery, so finding a fast way to measure it could help docto…

This study looks at whether a quick frailty screening tool (ISAR) can identify older adults in the emergency department who are at risk for medication problems, like harmful drug interactions or inappropriate prescriptions. Researchers will collect medical data from 300 patients …

This study looks at a new way to give recommended vaccines to adults with chronic diseases or weakened immune systems. Doctors will offer vaccines during hospital visits, admissions, or at discharge. The goal is to see how many patients accept and complete their vaccines, and to …

This study checks if a short questionnaire called G8 can accurately identify frailty in people aged 70 and older with solid tumors. Researchers will compare the G8 results with a full medical exam to see how well the tool works. The goal is to help doctors in Portugal quickly spo…

This study looks at 400 older adults (65+) having planned hip replacement surgery in the Czech Republic. Researchers want to see if a short memory test given before surgery can predict who might become confused or delirious afterward. The goal is to make routine memory checks sta…

This study looks at whether a health tracking platform can help improve frailty in people over 65. Researchers will follow 1,000 seniors for a year to see if using the platform leads to better health. They also want to find the best ways to predict frailty so doctors can prevent …

This study aims to see if an AI system that analyzes emotions in a person's voice can help predict frailty and improve mental health in adults with congenital heart disease. Over three years, 410 participants will complete surveys and some will receive AI-guided counseling. The g…

This study looks at the health, nutrition, and daily living of 330 older adults (60+) in a rural Egyptian village. Researchers will interview participants and do simple physical checks to find common health problems like chronic diseases, frailty, and malnutrition. No treatments …

This study looks at whether frailty can help predict bleeding in older adults (65+) who have had a heart attack or unstable angina. Researchers will follow 850 patients for up to 6 months to see if adding frailty to standard risk tools improves bleeding predictions. The goal is t…

This study looks at whether an electronic health assessment (eCGA) can help family doctors better understand frailty in adults aged 65 and older. About 120 participants will use the tool and some will also get a personalized exercise program. The goal is to see if this approach c…

This observational study will follow 228 elderly patients (65+) with a broken femur who are also frail. Some will receive a special oral nutritional supplement before surgery, while others get standard care. Researchers want to see if the supplement helps keep blood pressure stab…

This study will follow 4,000 intensive care patients aged 80 and older to understand how chronic and acute heart conditions affect their long-term recovery and quality of life. Researchers will use simple tests to measure frailty and daily living skills. The goal is to better pre…

This study looks at how HIV might speed up aging. Researchers will compare frailty, muscle loss, nutrition, thinking, and physical function in 80 adults aged 40 and older—half with HIV and half without. The goal is to understand if people with HIV face these age-related problems …