Sniff and sweat: new study tests simple ways to keep aging brains sharp
NCT ID NCT07623122
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether smell training and/or physical exercise can improve thinking, movement, and quality of life in healthy adults aged 60 and older. About 120 participants were split into four groups: usual care, smell training, exercise, or both. The goal was to understand how these activities affect the brain and body, not to treat a disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
120 people
The number who actually took part.
- Started
-
Jun 2024
- Finished
-
Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
60 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Adults aged ≥60 years under the care of Primary Care and/or the Geriatrics Service of the Hospital Universitario de Navarra; * Normal cognitive function as determined at baseline assessment (Mini-Mental State Examination \[MMSE\] score ≥23; ≥21 for individuals without formal education); * Fluent in speaking, reading, and understanding Spanish; * Adequate olfactory function; * Adequate visual and auditory acuity to complete neuropsychological and computerized assessments; * In good general health, with no condition expected to interfere with study participation; * Willing and able to comply with study procedures and to participate for the entire study duration; * Willing to refrain from the use of scented candles, essential oils, or air fresheners during study participation. Exclusion Criteria * Refusal or inability of the participant, primary caregiver, or legal representative to provide informed consent; * Diagnosis of a neurodegenerative disease or severe dementia (Global Deterioration Scale \[GDS\] stage 6-7); * Conditions affecting the olfactory system (e.g., nasal polyps); * Life expectancy \<3 months; * History of asthma, allergies, or olfactory-triggered responses producing allergy-like symptoms (e.g., rhinorrhea, lacrimation, sneezing, or skin rash); * History of neurological disorders such as Parkinson's disease, multiple sclerosis, brain cyst, tumor, or aneurysm; * Significant medical conditions, including uncontrolled diabetes mellitus, uncontrolled hypertension, nutritional deficiencies, or thyroid disorders; * History of major psychiatric disorders such as schizophrenia, bipolar disorder, anxiety disorders, or attention-deficit/hyperactivity disorder; * History of alcohol or substance abuse or dependence within the past 2 years (DSM-IV criteria), including use of cigarettes, e-cigarettes, cigars, marijuana, or any substance that may produce odors interfering with the study.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cognitive decline are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Universitario de Navarra
Pamplona, Navarre, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can sharing old memories boost mental Well-Being in old age?
- Can a Hands-On reflex therapy steady an older Person's stance?
- Can immune aging blood tests predict which older IBD patients thrive on advanced therapies?
- Walking buddies: can volunteers keep hospital patients strong?
- Could a frailty score predict which older cancer patients survive intensive care?
- 150,000 children to be tracked from birth to old age in massive health study