HEALTHY AGING

This study explores whether a simple smell test can help detect early signs of Alzheimer's and other brain diseases. Researchers will have 250 adults with mild memory or behavior concerns, plus healthy older adults, take a 45-minute at-home smell test. The goal is to develop a lo…

This study looks at whether different types of exercise can improve brain health and reduce the risk of Alzheimer's disease in older African Americans. Researchers will compare a cardio-dance fitness program to a strength, flexibility, and balance program over six months. Partici…

This study tests whether a daily dietary supplement can improve memory, thinking, and emotional well-being in healthy adults aged 55 and older. Sixteen participants will take the supplement for 45 days and complete memory and mood tests at the start and end. The goal is to see if…

This study tests a wearable robotic exoskeleton to see if it can improve mobility, balance, and walking in healthy older adults and people with Parkinson's disease, who are at high risk for falls. About 26 participants will attend two lab sessions to perform tasks like walking an…

This study looks at language problems in people with Lewy body disease (like Parkinson's or dementia with Lewy bodies) who also have mild cognitive impairment. Researchers will first compare how these individuals understand sentences versus healthy older adults. Then, they will t…

This study tests whether a daily drink containing inactivated lactic acid bacteria (a postbiotic called Humiome® Post LB) can reduce stress and improve thinking skills in healthy adults aged 50-75 who have mild memory complaints. Over 3 months, 236 participants will take either t…

This study tests whether a dietary supplement called Mitopure® (urolithin A) can improve muscle strength in healthy adults aged 40-65 who are not very active. About 120 participants will take either a low dose, high dose, or a placebo pill daily for 6 months. The main goal is to …

This study looks at whether neuroathletic exercises—movements designed to train the brain and body together—can improve walking speed, lower fall risk, and boost memory and thinking in healthy adults aged 60 to 80. About 60 participants will be split into two groups: one doing th…

This study tests whether taking collagen peptides daily for 6 months can help slow cellular aging in healthy adults aged 50-70 who are overweight and not very active. Researchers will measure changes in telomere length (a marker of aging), inflammation, body composition, and phys…

This study looks at whether a computer-based brain training program can improve thinking skills, memory, and emotional well-being in healthy older adults and those with mild cognitive impairment (MCI). About 156 Spanish-speaking adults aged 65 and older will take part. The goal i…

This study is creating a tool to estimate a person's 'biological age'—how old their body really is—rather than just counting birthdays. Researchers will collect health, lifestyle, and lab data from 3,500 volunteers across Russia. The goal is to better understand aging and help pr…

This study looks at how paying attention in different ways during calf-strength training affects walking in healthy older adults. Researchers will compare two types of external focus with an internal focus to see which leads to smoother, more automatic movement. Participants will…

This study explores whether mild low-oxygen (hypoxic) conditioning, alone or combined with exercise, can improve blood vessel health in the brains of inactive older adults aged 60-80. Researchers will measure changes in brain blood flow and other health markers. The goal is to fi…

This study is gathering information from 100 adults aged 30 and older who are members of the Wellness Institute in Manitoba. Researchers will measure things like fitness, diet, sleep, stress, and overall health to understand how lifestyle and gym use relate to healthy aging. No t…

This study trains palliative care doctors to better understand and address racism in healthcare. Researchers will work with 60 African American patients and their families to see if using storytelling videos and bias training improves the quality of care. The goal is to make end-…

This study is testing whether combining fasting with regular exercise can slow the aging process in people over 65. Researchers will measure biological age using DNA markers and other health indicators over one year. 240 participants will be split into four groups: exercise only,…

This study explores whether playing a web-based game called the Breakfast Game can improve multitasking and other thinking skills in healthy adults aged 60-75. Participants will attend one educational session and 10 one-hour game sessions over a month, with follow-up tests after …

This study aims to help older adults in rural Taiwan live healthier, more active lives by using wearable devices and a mobile app. Researchers will track sleep, activity, and health data from 140 participants to understand aging better. The goal is to create a digital database an…

This early-phase study looks at how a natural cell process called autophagy affects small blood vessel function in adults with type 2 diabetes. Researchers will compare 60 participants with and without diabetes, giving some a supplement called trehalose (thought to boost autophag…

This study tests whether a weak electrical current applied to the neck or upper back can change how muscles work and how tired they get. Forty healthy adults aged 18 to 50 will take part in up to six sessions. Researchers will measure muscle force, effort, and activation to see i…

This study is testing whether a probiotic called iVS-1 can slow down biological aging in healthy adults aged 40 to 75. Researchers will measure changes in aging-related genes and blood markers over time. The goal is to see if improving gut health can help people stay healthier as…

This study will follow 5,000 middle-aged and older Tzu Chi volunteers in Taiwan to see how vegetarian and plant-based diets affect healthy aging. Researchers will measure thinking skills, muscle mass, grip strength, and signs of frailty. The goal is to learn which eating patterns…

This study tests whether a gentle, non-invasive brain stimulation technique called rTMS can improve motivation, memory, and brain function in healthy older adults and people with very early Alzheimer's disease. Participants will receive daily stimulation sessions for two weeks, w…

This study is testing whether a personalized health and behavior program can slow or reverse biological aging in healthy adults over 50. About 1,500 participants will be randomly assigned to either receive a custom intervention plan or just standard assessments. The goal is to se…

This study looks at two teaching methods to help adults over 50 use the 'My Health Bank' health app. One group gets one-on-one tutoring, the other uses self-study materials created with AI. The goal is to see which approach better improves digital health skills and confidence.

This study follows 5,000 adults in Hong Kong who either have or are at high risk for brain diseases like stroke and dementia. Researchers will collect medical records, surveys, and phone interviews over many years to identify what factors lead to these conditions. The goal is to …

This study checks if people can use a home kit to measure levels of urolithin A in their blood after taking Mitopure. About 250 healthy adults aged 18 to 80 will collect a small blood sample at home and send it in. The goal is to see if the kit works reliably and is easy to use.

This study looks at whether a series of balance exercises can help healthy older adults better sense motion and improve their balance. Thirty participants will practice tilting and moving on a special platform over about 45 days. The goal is to understand how the inner ear's sens…

This study looks at how healthy aging changes the way our brains process time. Researchers will compare young adults (20-35) and older adults (60-85) using brain scans and timing tasks. The goal is to understand why time perception declines with age and find new ways to measure t…

This study looks at how a 6-month program of exercise, mindfulness, and nutrition affects thinking, inflammation, sleep, and physical health in 60 healthy adults aged 50 to 75. Participants either start the program right away or wait 6 months before starting. The goal is to under…

This study looks at whether people with Alzheimer's disease have more trouble swallowing than healthy older adults. Researchers will test swallowing, coughing, and muscle strength in 240 participants, and ask caregivers about their experiences. The goal is to better understand ho…

This study uses powerful MRI scanners to look at the brains of 700 people, including those with conditions like multiple sclerosis, Alzheimer's, and Parkinson's, as well as healthy volunteers. The goal is to understand why some brains stay healthy while others develop disease. Re…