HEALTHY AGING

This study looks at how different types of exercise affect brain health and Alzheimer's risk in older African Americans. About 280 people aged 60 and older who are not very active will either take cardio-dance classes or strength, flexibility, and balance classes for 6 months. Re…

This study explores whether a simple, at-home smell test can help detect early signs of Alzheimer's and other brain diseases. Researchers will ask 250 adults with mild memory or behavior concerns, as well as healthy older adults, to take a 45-minute smell test using scratch-and-s…

This study tests whether playing a web-based game called the Breakfast Game can improve multitasking and other thinking skills in healthy adults aged 60-75. Participants will complete 10 one-hour training sessions over a month, plus assessments before, after, and three months lat…

This study tests whether a 45-day balance training program can help healthy older adults better sense body tilts and movements, and improve their balance. Participants will sit on a moving platform and practice identifying directions of motion while getting feedback. The goal is …

This study is testing whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and people with Parkinson's disease. About 26 participants will attend two lab sessions to try the device and perform tasks like walking and standing. T…

This study looks at how people with Lewy body disease (including Parkinson's and dementia with Lewy bodies) understand sentences. Researchers will compare their language skills to healthy older adults and then test whether a gentle, noninvasive brain stimulation treatment done at…

This study looks at whether neuroathletic exercises—movements designed to train the brain and body together—can improve walking speed, lower fall risk, and boost memory and thinking in healthy adults aged 60 to 80. About 60 participants will be split into two groups: one doing th…

This study tests whether taking a daily postbiotic (inactivated lactic acid bacteria) called Humiome® Post LB for three months can lower stress and improve memory in healthy adults aged 50 to 75. About 236 participants will receive either the supplement or a placebo. The main goa…

This study tests whether a daily dietary supplement can improve memory, thinking, and emotional well-being in healthy adults aged 55 and older. Sixteen participants will take the supplement for 45 days and complete memory and mood tests at the start and end. The goal is to see if…

This study is testing whether a dietary supplement called Mitopure® (urolithin A) can improve muscle strength in healthy adults aged 40 to 65 who are not very active. Participants will take either a low or high dose of the supplement or a placebo daily for 6 months. The main goal…

This study looks at how a 6-month program of exercise, mindfulness, and nutrition affects thinking, inflammation, sleep, and physical health in 60 healthy adults aged 50 to 75. Participants either start the program right away or wait 6 months before starting. The goal is to under…

This study looks at how healthy aging changes the way our brains process time. Researchers will compare young adults (20-35) and older adults (60-85) using brain scans and timing tasks. The goal is to understand why time perception declines with age and find new ways to measure t…

This study tests whether a weak electrical current applied to the neck or upper back can change how muscles work and how tired they get. Healthy adults aged 18 to 50 will attend up to 6 sessions to measure muscle force, effort, and activation. The goal is to understand the effect…

This study looks at whether people with Alzheimer's disease have more trouble swallowing than healthy older adults. Researchers will test swallowing, coughing, and muscle strength in 240 participants, and ask caregivers about their experiences. The goal is to better understand ho…

This study checks if people can use a home kit to measure levels of urolithin A in their blood after taking Mitopure. About 250 healthy adults aged 18 to 80 will collect blood samples at home and send them for analysis. The goal is to see how reliable the kit is and if it can be …

This study tests two teaching methods to help adults over 50 use the 'My Health Bank' health app. One group gets one-on-one tutoring, the other uses self-study materials created with AI. The goal is to see which approach better improves digital health skills and confidence.

This study tests whether combining fasting with exercise can slow the aging process in healthy adults over 65. Two hundred forty participants will be split into four groups: exercise only, fasting only, both, or neither. Researchers will measure biological age using DNA markers a…

This study is testing whether a probiotic called iVS-1 (a type of friendly bacteria) can help slow down aging in healthy adults aged 40 to 75. Researchers will measure changes in biological age markers and overall health over time. The goal is to learn if improving gut health can…

This study looks at how vegetarian and plant-based diets affect healthy aging in 5,000 middle-aged and older adults in Taiwan. Researchers will measure thinking skills, muscle mass, and strength to see if these diets help prevent age-related problems like frailty and memory loss.…

This study tests a training program for doctors and nurses who care for older African American patients at the end of life. The training uses videos and guidelines to help clinicians understand patients' cultural values and recognize their own biases. The goal is to improve commu…

This study looks at whether taking collagen peptides every day for six months can help slow aging in healthy adults aged 50 to 70 who are overweight and not very active. Researchers will measure changes in telomeres (parts of our cells linked to aging), inflammation, and body com…

This study looks at whether breathing low-oxygen air (hypoxic conditioning), either by itself or combined with exercise, can improve blood vessel health in the brains of older adults. Researchers will enroll 64 inactive people aged 60 to 80 to test this approach. The goal is to f…

This study uses powerful MRI scanners to look at the brains of 700 people, including those with conditions like multiple sclerosis, Alzheimer's, and Parkinson's, as well as healthy volunteers. The goal is to understand why some brains stay healthy while others develop disease. Re…

This study aims to create a biological age calculator specifically for the Russian population. Researchers will collect data from 3,500 healthy volunteers, including blood tests, physical exams, and cognitive tests, to understand how people age differently. The goal is to develop…

This study looks at whether a natural process called autophagy (cell cleanup) is reduced in people with type 2 diabetes and if that harms small blood vessels. About 60 adults (some with diabetes, some healthy) will take either trehalose (a sugar that may activate autophagy) or a …

This study is following 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk. Researchers will collect medical records and survey data over time to identify what factors lead to brain diseases. The goal is to find ways to keep br…

This study aims to understand how using a medical fitness facility and daily habits like diet, exercise, and sleep affect health as people age. Researchers will collect information from 100 adults aged 30 and older who are members of the Wellness Institute in Manitoba. No treatme…

This study looks at how focusing your attention differently during calf-strength exercises might change the way you walk. Researchers will compare two types of external focus (like thinking about moving a marker) with an internal focus (thinking about your own muscles) in healthy…

This study looks at whether a gentle, non-invasive brain stimulation technique called rTMS can improve motivation, memory, and brain function in healthy older adults and those with early signs of Alzheimer's. Participants will receive daily stimulation sessions for two weeks, wit…