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Sniffing out Alzheimer's: simple smell test could spot early brain changes

NCT ID NCT05881239

Recruiting now Diagnosis Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether a simple, at-home smell test can help detect early signs of Alzheimer's and other memory disorders. Researchers will ask 250 adults with mild memory or behavior concerns, as well as healthy older adults, to take a 45-minute scratch-and-sniff test using a smartphone app. The goal is to develop a low-cost, noninvasive tool that could one day help doctors identify brain diseases earlier.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Anosmia Cognitive Dysfunction Nerve Degeneration subjective cognitive decline

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY AGING MILD BEHAVIORAL IMPAIRMENT MILD COGNITIVE IMPAIRMENT SUBJECTIVE COGNITIVE CONCERNS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02129, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••