Sniffing out Alzheimer's: simple smell test could spot early brain changes

NCT ID NCT05881239

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study explores whether a simple, at-home smell test can help detect early signs of Alzheimer's and other memory disorders. Researchers will ask 250 adults with mild memory or behavior concerns, as well as healthy older adults, to take a 45-minute scratch-and-sniff test using a smartphone app. The goal is to develop a low-cost, noninvasive tool that could one day help doctors identify brain diseases earlier.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Anosmia Cognitive Dysfunction Nerve Degeneration subjective cognitive decline

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02129, United States

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Other studies related to the condition(s) this trial covers.