HEALTHY AGING

This study is testing whether two different exercise programs—cardio-dance fitness versus strength, flexibility, and balance training—can improve brain health and reduce Alzheimer's disease risk in older African Americans. Researchers will enroll 280 sedentary adults aged 60+ to …

This study is testing whether a daily probiotic supplement can improve markers of healthy aging in adults aged 40-75. Researchers will measure changes in blood tests, gut bacteria, and quality of life surveys over five months. Participants will be randomly assigned to receive eit…

This study investigates whether fasting, exercise, or both can slow biological aging in healthy adults over 65. 240 participants will be randomly assigned to different groups for one year. Researchers will measure aging markers in blood, fitness, and body composition to see which…

This study is testing whether a 45-minute smell test can help detect early signs of Alzheimer's disease. Researchers want to see if changes in a person's sense of smell can predict who might develop memory problems. Participants will sniff different odors and answer questions abo…

This study is testing whether playing a specific online brain training game can help maintain thinking skills in healthy older adults. Researchers want to see if practicing multitasking in the game improves daily mental abilities and could potentially help reduce the risk of futu…

This study is testing whether a daily supplement containing inactivated 'good' bacteria, called a postbiotic, can help reduce feelings of stress and anxiety and improve memory and thinking skills in healthy adults aged 50 to 75. About 236 participants will take either the postbio…

This study is testing whether a special type of exercise, called neuroathletic exercise, can help older adults walk faster, lower their risk of falling, and improve their memory and thinking skills. Researchers will compare a group doing these brain-focused exercises to a group f…

This study is testing whether a safe, non-invasive brain stimulation technique can help improve motivation and memory in older adults, including those with very early signs of Alzheimer's disease. Researchers will use a device called rTMS to gently stimulate a brain area involved…

This study is testing whether a dietary supplement called Mitopure® can help improve muscle strength and physical performance in healthy middle-aged adults. It will involve 120 participants, aged 40-65 with low activity levels, who will take either the supplement or a placebo dai…

This study is testing whether a daily liquid dietary supplement can improve memory, focus, and mood in healthy adults aged 55 and older. Participants will take the supplement or a control drink for 45 days and complete memory and mood tests at the start and end. The goal is to se…

This study aims to understand and potentially treat language comprehension problems in people with Lewy body diseases like Parkinson's. Researchers will first map how the brain processes sentences in 90 older adults, comparing patients to healthy peers. Then, they will test if a …

This study aims to understand how the brain's ability to judge time changes as people get older. Researchers will recruit 130 healthy adults, both young and older, to perform time-judgment tasks while their brain activity is measured using EEG, MRI, and PET scans. The goal is to …

This study is testing how well a home health kit works for people to collect their own blood samples. Researchers want to see if the kit reliably measures levels of a compound called Urolithin A, which comes from a dietary supplement called Mitopure. The goal is to understand if …

This study aims to follow 5000 adults over many years to understand what factors lead to brain diseases like stroke and dementia. It will track people who already have a diagnosis, are at high risk, or are currently healthy, using questionnaires and medical records. The goal is t…

This study is testing whether training older adults to better sense body movements can improve their balance. Researchers will have 30 healthy adults aged 65-89 practice detecting tilts and side-to-side motions while receiving feedback. The goal is to understand if this type of t…

This study aims to gather initial information to plan a larger, long-term research project on healthy aging. Researchers will collect detailed health and lifestyle data from 100 adults aged 30+ who are members of a specific wellness center. The goal is to understand the connectio…

This study aims to understand how a natural cellular cleanup process, called autophagy, affects the function of tiny blood vessels in people with Type 2 Diabetes. Researchers will compare 60 adults, some with diabetes and some healthy, by testing their blood vessel function befor…

This study aims to understand how a person's mental focus during leg strength training affects their walking patterns and related brain activity. Researchers will enroll 45 healthy older adults to compare different mental focus strategies during calf muscle exercises. The goal is…

This study aims to understand how the brain changes and adapts in various neurological conditions and during normal aging. Researchers will use advanced, high-powered MRI scans to look at brain structure, function, and energy use in 700 participants, including people with disease…