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Scientists scan brains to unlock why time feels different as we age

NCT ID NCT06349213

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how aging changes the way we perceive time. Researchers will use brain scans (EEG, fMRI, and PET) to compare time judgment in healthy young adults (20-35) and older adults (60-85). The goal is to understand the brain mechanisms behind age-related changes in time processing, which could help identify early signs of cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Fluorodopa (FDOPA) injection for PET imaging
What this could lead to
If successful, this could help identify brain changes related to time perception in aging, potentially leading to early markers for cognitive decline.
What could go wrong
This is an observational study, not a treatment trial. It is small (130 participants) and focuses on healthy individuals, so results may not apply to those with cognitive impairments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Nov 2030

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy participant with no diagnosed condition

Ages

20 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Membership of a social security scheme or beneficiary of such a scheme. 2. At least 7 years' schooling. 3. Acceptance and signature of the informed consent form 4. Fluency in French (as assessed by the project leader) 5. Age between 20 and 35 years inclusive for young healthy subjects, and between 60 and 85 years inclusive for elderly healthy subjects. 6. Effective contraception for women of childbearing age: Contraception will be considered effective from the moment the participant declares taking an oral contraceptive, the presence of an IUD, diaphragm or contraceptive implant, or the performance of a tubal ligation or sterilisation. 7. Absence of global cognitive deficit attested by a score on the MOCA scale greater than or equal to 26/30. Exclusion Criteria: 1. Persons under guardianship, curators or safeguard of justice. 2. Pregnant women, women in labor and nursing mothers 3. Chronic neurological conditions 4. Uncorrected visual difficulties 5. Encephalitis 6. Endocrine or liver disease 7. History of head trauma with loss of consciousness lasting more than one hour 8. History of cancer in the last 5 years, with the exception of squamous cell carcinoma of the skin 9. Presence or history of chronic alcoholism or drug addiction 10. Presence of clinically significant major psychiatric disorders (according to DSM-IV-TR criteria) or symptoms that could affect the participant's ability to complete the research. 11. Use of medications that may modulate the dopaminergic system (psychotropic, with the exception of sleeping pills or occasional use of anxiolytics, as decided by the principal investigator). 12. Contraindications to MRI examination (pregnancy; pacemaker or neurosensory stimulator or implantable defibrillator; clip on an aneurysm or clip on a vascular malformation of the brain; intraocular or cerebral ferromagnetic foreign body; prosthesis or mobilizable ferromagnetic metal object or splinter; cochlear implant ; peripheral stimulator; neurosurgical ventriculoperitoneal shunt valves; permanent eyelid or lip make-up; jewelry or piercing that cannot be removed; certain tattoos depending on the type of ink, size and location; automated injection devices such as insulin pumps, blood glucose sensors, claustrophobia). 13. Radiotracer contraindications: Hypersensitivity to product excipients, chronic alcoholism, kidney disease. 14. Participation in research involving exposure to ionizing radiation (nuclear medicine or radiology examinations) in the year preceding inclusion or during a period of exclusion from other research.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Cyceron Boulevard Henri Becquerel

    RECRUITING

    Caen, 14074, France

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