Lifestyle trio tested for sharper aging
NCT ID NCT06516146
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a combined program of online exercise classes, guided meditation, and nutrition advice can improve brain function, reduce inflammation, and enhance physical fitness in healthy adults aged 50 to 75. Sixty participants will either start the 6-month program right away or wait 6 months before starting. Researchers will measure changes in thinking, sleep, mood, body composition, and more.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise, meditation, and nutrition
- What this could lead to
- If it works, this could point toward a simple lifestyle program to help people stay sharp and healthy as they age.
- What could go wrong
- This is a small, early study with no control group for the main comparison, so results may not be conclusive or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants who are able to complete questionnaires and follow directions for interventions * Have access to a smartphone that can support the Fitbit app Exclusion Criteria: * Any neurological disease/disorder diagnosis (Ex: Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, Brain lesion, Stroke, etc) * Any chronic medical condition which would affect ability to participate in exercise * Any contraindication for exercise based on the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and medical clearance form * Participants who were told by a medical doctor that they need to be medically supervised for exercise * Montreal Cognitive Assessment (MoCA) scores \<21/30 * Significant cognitive impairment, depression, or eating disorder * Any contraindication to MRI scanning; such as implanted metal clips or wires (see list below) * Participants currently doing 180 minutes or more of moderate-vigorous intensity exercise per week AND either of the following: * Completion of an Mindfulness-Based Stress Reduction course OR; Score \>8/15 in the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) Diet Questionnaire * Significant or unstable cardiovascular or respiratory disease * Severe/multiple head trauma(s) * Subjects who are pregnant or breastfeeding * Subjects with a history or major episodes of drug or alcohol abuse * Chronic/acute bacterial/viral infection * GI cancer * Inflammatory bowel disease Exclusion for MRI scanning: * Individuals weighing \> 400 lbs (limit of MRI machine) * Artificial heart valve * Brain aneurysm clip * Electrical stimulator for nerves or bones * Ear or eye implant * Implanted drug infusion pump * Coil, catheter, or filter in any blood vessel * Orthopedic hardware (artificial joint, plate, screws) * Other metallic prostheses * Shrapnel, bullets, or other metal fragments * Surgery or tattoos (including tattooed eyeliner) in the last six weeks * Brain surgery * Have a cardiac pacemaker, wires or defibrillator * Have had an injury where a piece of metal lodged in the eye or orbit * Have a ferromagnetic aneurysm clip
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of British Colombia
RECRUITINGVancouver, British Columbia, V6T 1Z3, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A spoonful of peanut butter a day to keep the mind sharp?
- Talking yourself into fitness: could Self-Talk boost walking in seniors?