DEPRESSIVE SYMPTOMS

This study tested whether a physical activity program delivered by mail and phone could help older women prevent serious health problems like heart attacks, strokes, hip fractures, and falls. About 50,000 women already in the Women's Health Initiative took part. The program provi…

This study tested an online mentoring program for transgender and gender minority youth ages 14 to 18. The program paired each teen with an adult transgender mentor for seven group sessions focused on building social and emotional skills. The goal was to prevent problems like dru…

This study looked at whether taking daily vitamin D or fish oil supplements could help prevent depression in over 18,000 healthy adults. Participants took either supplements or a placebo for about five years. The results showed that neither vitamin D nor fish oil reduced the risk…

This study tested an online program called PROCARE-I+ for 30 teens showing early signs of anxiety or depression. The program helped improve their emotional health, quality of life, and ability to manage feelings. It aims to prevent full-blown emotional disorders from developing.

This study tested two audio-based digital programs to help adults with moderate or worse depression. 101 participants were randomly assigned to either a behavioral activation program or a self-monitoring program. Depression symptoms were measured before, during, and after the 2-w…

This study tested a computer-assisted therapy program called Raising Our Spirits Together (ROST) for adults with mild depression in rural Michigan. Participants joined small groups led by local pastors, either online or in person. The goal was to see if this approach could reduce…

This study tested two psychological treatments for adults with mild anxiety and depression in Spanish primary care. 136 people were randomly assigned to either a 10-week group program or a single one-hour session. The goal was to see which approach better reduced symptoms over 12…

This study looked at whether walking in nature reduces depressive symptoms more than walking in a city. 138 college students with mild to moderate depression walked for 30 minutes twice a week for three weeks. Some walked in nature, some in the city, and some did guided nature wa…

This study tested whether a cultural arts program could reduce depressive symptoms and age-related self-stigma in older adults. 63 people aged 60 and older who were at risk for depression took part. The program involved creative arts activities, and results were compared to usual…

This study tested whether a culturally adapted internet-based cognitive behavioral therapy (iCBT) program could help reduce symptoms of depression, anxiety, insomnia, and trauma in Arabic-speaking refugee and migrant youth aged 15-29. 125 participants were randomly assigned to re…

This study tested a mobile web-based program to help caregivers of people with Alzheimer's disease feel less depressed and stressed. 184 caregivers who provided at least 20 hours of in-home care per week and had mild depressive symptoms participated. The program aimed to improve …

This study tested a 6-week program based on cognitive behavioral therapy (CBT) for 255 caregivers of older adults in Hong Kong. The program aimed to reduce stress, depression, and anxiety by teaching coping skills and communication techniques. Researchers compared the program gro…

This study looked at whether a faith and prayer mobile app called PRAY.COM could help university students feel better mentally and emotionally. About 450 students used the app for at least 10 minutes each day over 8 weeks. The goal was to see if students would use it regularly an…

This pilot study tested a 10-session behavioral activation program delivered via teletherapy to help adults with moderate-to-severe depression increase physical activity and reduce depressive symptoms. Sixty-five participants used a smartphone and Fitbit to track activity. The st…

This study tested an electronic mental health program (e-MHP) to see if it can reduce depressive symptoms in adults. 70 people took part, including those with mood disorders and healthy volunteers. The program was delivered online and aimed to make mental health support more acce…

This study looked at whether taking aspirin and ketamine by mouth at the same time can help people with depression that hasn't improved with other treatments. Fifteen adults with treatment-resistant depression received the combination alongside their usual antidepressant. The mai…

This study tested a version of cognitive behavioral therapy (CBT) that was adapted to fit the culture of earthquake survivors in Türkiye. 60 adults who experienced the earthquake and had high levels of distress took part. The therapy aimed to reduce their psychological distress, …

This study tested whether inhaling lavender essential oil for 20 minutes before orthopedic surgery could reduce anxiety, stress, and depression. 128 adult patients in Jordan took part, with half receiving lavender and half receiving routine care. Results showed that the lavender …

This study tested a school-based program to help teenagers with mild to moderate depression, anxiety, or stress. The program teaches skills like psychological flexibility and resilience using Acceptance and Commitment Therapy (ACT). 61 teens took part, and researchers compared th…

This study tested whether 10 months of flywheel resistance training (a type of exercise that focuses on muscle lengthening) is better than traditional resistance training for reducing depressive symptoms and improving physical and thinking abilities in older women who are sedenta…

This pilot study tested whether a smartphone-based cognitive behavioral therapy (CBT) program could help adults with both psoriasis and depression symptoms. Thirty participants used an 8-week coach-guided app. The study measured how many people completed the program, their satisf…

This study tested a program called DAPPER for African American women aged 50 and older who had pain, depressive symptoms, and trouble moving around. Participants received 8 nurse visits at home to help manage their pain and mood. The study measured changes in pain intensity and d…

This study tested a 5-week group program called Rare Group Problem Management Plus (PM+) for parents or guardians of children with rare diseases. The program aims to help with stress, anxiety, depression, and emotional problems. Eight participants joined online sessions and compl…

This study tested a mobile phone program to help children with cancer and their families build psychological resilience and improve mental well-being. Forty participants used the app, and researchers measured changes in anxiety, depression, and overall mental health. The goal was…

This study tested whether a probiotic called Lactobacillus reuteri can lower stress, anxiety, and depressive symptoms in adults aged 18-45 who feel stressed. 150 participants took either the probiotic or a placebo for a period, and researchers measured changes in perceived stress…

This study explored whether daily training with different odors can improve both smell function and emotional well-being in people with mild depressive symptoms or major depression. Researchers enrolled 150 participants, including healthy volunteers and depressed patients, who pr…

This study tested a type of talking therapy called Cognitive Processing Therapy (CPT) to help adults in Turkey who were struggling with PTSD, anxiety, and depression after the 2023 earthquakes. 36 survivors took part, with some receiving CPT and others getting usual care. The goa…

This study tested a stepped-care program delivered by phone to help cancer survivors living in rural areas manage emotional distress like anxiety and depression. 68 adults who had finished cancer treatment within the past 6 to 60 months took part. The program offered low- or high…

This study tested a program called COPE (Coping Options for Parent Empowerment) for parents of teenagers in Spain. The goal was to see if it could help parents feel less anxious, depressed, and stressed, and improve their parenting skills. Twenty-six parents attended group sessio…

This study looked at how college students with mild-to-moderate depressive symptoms handle stress. Researchers tested a text-message program that sent weekly surveys and personalized feedback to help students notice stress early. 120 students took part, with some receiving the te…

This study looked at 56 adults who had fully recovered from depression and wanted to stop their antidepressant. Researchers wanted to see if how much you expect to have withdrawal symptoms affects how bad they actually are. Some people stopped their medication openly, some secret…

This study looked at which combination of support programs works best to reduce suicidal thoughts and build resilience in American Indian youth ages 10-29 who are at risk for suicide. Researchers tested different sequences of three programs: New Hope, Elders Resilience, and Case …

This study looked at whether community health workers visiting pregnant women at home in rural South Africa could improve health for both mothers and children. About 1,490 women took part, with some areas getting the home-visit program and others not. Researchers tracked things l…

This study followed 1290 adults with type 1 or type 2 diabetes for two years to see how mental health issues like depression, anxiety, and eating problems relate to blood sugar control. Participants completed surveys, interviews, and daily smartphone check-ins about mood and stre…

This study looked at whether adding folic acid and vitamin B12 to locally made cereals could improve the health of teenage girls in rural Ethiopia. About 472 girls aged 13-19 took part. The goal was to see if this simple, small-scale approach could boost vitamin levels, thinking …

This study looks at 128 children who were part of an early intervention program for neglect. Researchers are now following them into adolescence to measure brain activity, stress responses, depression, and risky behaviors. The goal is to understand how early support affects long-…

This small pilot study looked at how quickly flavonoids from blueberries enter the body and whether they can reduce inflammation in older adults (65+) who have mild depressive symptoms. Six participants each tried two different doses of blueberry powder. The goal was to see if hi…

This study tested a free online program designed to improve mental well-being in people with myasthenia gravis, a chronic muscle weakness condition. 77 participants watched four short video lessons about building social support, managing emotions, and finding personal meaning. Re…

This small study tested a type of talk therapy (RFCBT) that helps people break the cycle of repetitive negative thinking, called rumination. Researchers wanted to see if reducing rumination could also lower depressive symptoms and blood pressure in 9 low-income adults. The goal w…

This study tested two emotion regulation strategies—reconstrual (changing how you think about a situation) and repurposing (finding a new use for your feelings)—to see which better reduces sadness or anxiety in young adults aged 18 to 30. Over 200 participants completed online ta…

This study tested a program called RISE for young men leaving prison. The program provides trauma counseling and help finding a job and housing. Researchers wanted to see if this support would improve their mental health and stability, and lower the chance they would go back to p…