Sleep disorder

This study tests whether a 12-week program of supervised exercise, Mediterranean diet education, and stress management workshops can improve health in 120 overweight or obese adults. Participants will wear a smart bracelet to track activity and sleep. Researchers will measure cha…

This trial explores whether an archery exercise program can improve sleep quality, emotional well-being, and brain function in college students who have depressive symptoms. Participants will be randomly assigned to either an 8-week archery training program or their usual routine…

This study looks at whether improving sleep habits can help teenagers with overweight or obesity better regulate blood sugar and energy. Researchers will enroll 60 teens aged 14-19 who get less than 7 hours of sleep on school nights. For two weeks, participants will follow a slee…

This study tests a program called On Track for Wellness, which combines Fitbit activity trackers with health education and goal setting. The goal is to help 365 people recently diagnosed with psychosis improve their sleep and increase physical activity. Researchers want to see if…

This study compares a new software, C. Santé, to the standard sleep test (polysomnography) to see if it can accurately measure sleep quality. The software uses sensors on a bed to track breathing and heart rate without disturbing sleep. If successful, it could allow people to mon…

Many preschoolers with neurodevelopmental disorders struggle with sleep, which can worsen behavior and stress at home. This Hong Kong trial compares two ways of teaching parents sleep strategies: group sessions in person and a self-help mobile app, both added to usual care, again…

This study looks at two ways to improve sleep after breast cancer surgery: a nerve block injection or a mild ear stimulation device. About 136 women will be randomly assigned to one of the two treatments. Their sleep will be tracked with a wrist monitor and questionnaires for the…

This study tests whether feeding preterm infants breast milk at the same time of day it was expressed can improve their sleep in the NICU. Researchers will compare this circadian-synchronized feeding approach to routine feeding in 120 preterm infants born between 28 and 36 weeks.…

This pilot trial tests whether a 12-week home-based exercise program, called ASK, is feasible and beneficial for postpartum women who had high blood pressure during pregnancy. The program combines aerobic exercise, strength training, and Kegel exercises, guided by a mobile app an…

This trial tests whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve sleep quality in adults undergoing surgery for lung cancer. Participants with poor sleep before surgery will receive either active rTMS or a sham (inactive) treatment over five …

This trial tests whether a smartphone-based mindfulness program can help adolescents and young adults with sickle cell disease manage chronic pain and sleep problems. Participants are randomly assigned to either use the mindfulness app for about 8 weeks or receive usual care. The…

This trial tests whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve sleep quality in adults recovering from a lung transplant. Participants with sleep problems during their hospital stay will receive either active rTMS or a sham (inactive) treat…

This trial tests whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve sleep quality in adults with advanced non-small cell lung cancer who have trouble sleeping during hospital stays. Researchers will randomly assign 160 participants to receive ei…

This study tests whether a handheld robot that guides meditation with touch and voice can improve sleep quality in older adults with mild memory concerns. 100 participants will either use the robot or a standard meditation app for daily sessions. The goal is to see if the robot h…

This trial tests whether Sleep Island, a WeChat mini-program for parents, can help preschool children sleep longer. Researchers will randomly assign 122 families to either use the app for 4 weeks or receive standard sleep education. The app tracks the child's sleep, gives persona…

This trial tests whether a 6-week massage therapy program can improve sleep quality and reduce pain in active-duty service members with chronic back, neck, or shoulder pain. Participants receive either the massage sessions or usual care, and researchers track changes in pain inte…

This trial is testing whether a combination of Bao Yuan Tang, a traditional Chinese medicine extract, and galactooligosaccharides, a type of prebiotic, can improve sleep quality, reduce fatigue, and support better metabolism in female nurses who work night shifts. The study will …

This study tests a nurse-led program to reduce stress and improve sleep for patients in the intensive care unit (ICU). The program includes lowering noise, dimming lights at night, and grouping care tasks to avoid waking patients. About 68 awake adults will either receive this pr…

This large citizen-science trial is testing whether two prebiotic products can reduce feelings of anxiety and improve related outcomes like sleep in adults. Around 1,000 participants will be randomly assigned to take either an active prebiotic or a placebo for 12 weeks, without k…

This study tests whether a gentle, non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve sleep and reduce anxiety in adults over 60 who have chronic insomnia. Sixty participants will receive tACS sessions, and researchers …

This study looks at whether improving sleep can help memory and thinking in older adults with mild memory problems and sleep issues. Fifty participants aged 60-85 will receive either talk therapy for insomnia or gentle sound stimulation during sleep. Researchers will track change…

This trial tests whether taking melatonin before and after hip replacement surgery can improve sleep quality. 150 adults scheduled for elective hip replacement will receive either 5 mg, 10 mg, or a placebo pill. Sleep quality will be measured using a standard questionnaire.

This trial tests an 8-week eHealth program called eMindExCare that combines mindfulness practices with home-based aerobic and resistance exercises for prostate cancer patients undergoing active treatment. The study aims to see if the program is feasible and acceptable, and whethe…

This trial tests whether a six-week personalized behavioral sleep program, called ISleepFAST, can improve sleep and daily functioning in adults who have had a stroke and still struggle with sleep or circadian problems. Forty participants will be randomly assigned to either the sl…

This study tests whether a daily 200 mg dose of cannabidiol (CBD) for 12 weeks can reduce inflammation, ease pain, improve sleep, and boost quality of life in Brazilian Jiu-Jitsu athletes. One hundred healthy athletes aged 18-40 who train at least 3 times a week will be randomly …

This trial tests whether a concentrated beverage taken daily for 28 days can improve sleep quality in adults aged 18 to 60 with mild sleep issues. Participants keep sleep diaries and complete questionnaires on sleep quality and fatigue. The study uses a single-arm design, meaning…

This pilot study investigates whether melatonin can improve sleep quality in critically ill patients admitted to the ICU. Participants will wear a headband device to measure their sleep patterns and then receive a dose of melatonin. The study lasts two days and aims to see if mel…

This study tests whether a combination of Chinese herbal medicines, multivitamins, and amino acid supplements can improve mood and sleep quality in adults aged 18 to 65 who have mild emotional or sleep disturbances. Participants take either the active supplements or a placebo for…

This study tests a special device that monitors sleep without any physical contact, designed for people with Alzheimer's or related dementias living in long-term care facilities. About 100 residents will use the device for four weeks. Researchers want to see if sharing sleep data…

This study tests whether a dietary supplement called Radicle Energy VBM can help reduce fatigue and improve cognitive function, mental health, and sleep. Over 6 weeks, 550 adults will take either the active supplement or a placebo, without knowing which they received. The goal is…

This study looks at whether taking magnesium glycinate or magnesium L-threonate at night can improve sleep, recovery, and athletic performance in UCLA varsity athletes. 150 participants will take either a magnesium supplement or a placebo for 4 weeks. Sleep and recovery data will…

This study tests whether learning progressive muscle relaxation and deep breathing exercises can improve sleep for cancer patients receiving chemotherapy. About 40 adults aged 40-60 with poor sleep will be split into two groups: one gets relaxation training plus usual care, the o…

This study tests whether taking cannabidiol (CBD) every night for four weeks can improve sleep quality and reduce alcohol cravings and use. Fifty-eight adults with poor sleep and hazardous drinking will take either CBD or a placebo. Participants will wear activity monitors, compl…

This study compares two exercise approaches—short 'exercise snacks' spread throughout the day versus traditional aerobic exercise—in adults with moderate to severe obstructive sleep apnea. Researchers will measure sleep quality, daytime sleepiness, and physical function over 8 we…

This study will test a behavioral program to improve sleep and daily rhythms in autistic teenagers aged 13-17 who have sleep problems. The goal is to see if the program is practical and helps teens sleep better, which may also improve their mood and thinking. The study involves 1…

This study tests whether a nasal spray containing two medicines, dexmedetomidine and esketamine, can improve sleep quality and thinking abilities in older adults with mild-to-moderate Alzheimer's-related cognitive impairment and sleep problems. Sixty participants will receive eit…

This study tests a nurse-led program for insomnia that also uses a health education chatbot. 80 adults with sleep problems will either get the program plus chatbot or just track their sleep. The goal is to see if the chatbot-assisted approach improves sleep, anxiety, depression, …

This study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…

This study tests whether an artificial intelligence (AI)-guided sleep program is practical and well-liked by adults aged 60 and older who have both insomnia and mild memory concerns. Researchers will enroll 60 participants to check how many people join, stick with the program, an…

This study tests whether a non-invasive brain stimulation technique called temporal interference (TI) can reduce abnormal brain activity and improve sleep in adults with drug-resistant temporal lobe epilepsy. Twenty participants will stay in a sleep lab for six nights, receiving …

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study tests a brief sleep-focused workshop for people with PMDD who have trouble sleeping. The workshop teaches about sleep and simple strategies to improve it. Researchers want to see if it's practical and helpful, using sleep diaries and activity watches. 72 participants w…

This study tests whether a special smartwatch can improve sleep in warfighters who have trouble sleeping due to PTSD, traumatic brain injury, or stress. The watch detects signs of stress during sleep, like a fast heart rate, and gives gentle vibrations to calm the body without wa…

This study tests whether giving a single dose of the steroid dexamethasone during nasal surgery can improve sleep quality on the first night after the operation. About 102 adults having nasal surgery under general anesthesia will be randomly assigned to receive either dexamethaso…

This study tests two simple, drug-free ways to improve sleep for adults in the intensive care unit: playing pink-brown noise to mask hospital sounds, or a quiet time protocol with earplugs and eye masks. Researchers will track sleep using a wrist-worn smartwatch in 18 patients. T…

This study tests whether a nasal spray called dexmedetomidine, taken at night, can help older adults (ages 65-90) sleep and reduce the risk of delirium after major abdominal surgery. 400 participants will be randomly assigned to receive either the drug or a placebo. The goal is t…

This study tests whether a medication called dexmedetomidine can help patients in the intensive care unit (ICU) sleep more restfully. Good sleep is important for recovery, but ICU conditions often disrupt it. About 50 adult ICU patients will either receive the medication or a pla…

This study tests whether two relaxation techniques—Benson relaxation and progressive muscle relaxation—can help reduce pain and improve sleep quality in 160 patients who have had a lung lobectomy. Participants will practice these techniques after surgery, and their pain levels an…

This study tests a web-based program designed to help advanced cancer patients manage symptoms like depression, pain, fatigue, and sleep problems, while also supporting their caregivers. The program combines online tools with guidance from healthcare professionals. Researchers wi…

This study tests whether a mobile app or virtual reality program that teaches mindfulness and breathing exercises can lower stress, burnout, and improve sleep and thinking in nurses who work rotating shifts. 300 nurses will be split into four groups: one gets health education onl…

This study tests whether taking a daily probiotic supplement for 8 weeks can reduce stress and anxiety in healthy university students during exam time. Two hundred students will receive either the probiotic or a placebo. Researchers will measure changes in stress, anxiety, sleep …

This study tests whether a voice-based program called Talk Parenting, delivered through an Amazon Echo Dot, can help parents of children ages 3-5 improve challenging bedtime and morning routines. About 184 families will either use the program right away or wait 6 weeks. Researche…

This study tests a behavioral program called TranS-C to help autistic adults with sleep and circadian problems. The program teaches regular sleep routines, daytime habits, and helpful sleep beliefs. Researchers will enroll 24 autistic adults to see if the treatment improves overa…

This study tests whether two dietary supplements can help adults who are poor sleepers improve their sleep quality, thinking skills, and stress levels. Over 28 days, 68 participants will take either an active supplement or a placebo. Researchers will measure sleep efficiency, gut…

This study tests a gentle, non-invasive brain stimulation technique called so-tDCS in 80 older adults who have mild memory and sleep complaints. Participants will receive either real or sham stimulation over 4 weeks. Researchers will track changes in memory, sleep quality, and br…

This study tests whether a single session of sleep hygiene education can improve sleep quality and reduce pain in 100 adults with migraine or chronic lower back pain. Participants will learn healthy sleep habits and follow them for four weeks, tracking changes through questionnai…

This study tests whether a sleep medication called lemborexant can help older adults in the intensive care unit (ICU) sleep better and reduce their risk of delirium, a state of sudden confusion. The trial will involve 100 patients aged 65 and older who are in the surgical ICU. Pa…

This study tests whether using a virtual reality headset for guided relaxation after night shifts can improve sleep quality in nurses and nursing assistants. Forty participants will either use the VR device for one month or receive standard care, then switch. Sleep quality, insom…

This study looks at whether teaching people with rotator cuff syndrome the best sleeping positions can improve their sleep quality while they undergo physical therapy. Researchers will compare two groups: one getting standard physical therapy, and another getting physical therapy…

This study tests whether a small, home-use ear stimulation device can improve sleep and reduce stress in health sciences students who have trouble sleeping. Sixty students will either receive active stimulation or a placebo for three weeks. The goal is to see if this easy, non-in…

This study tests whether a warm foot bath on the night of abdominal surgery can reduce pain, improve sleep, and increase comfort. Around 96 adults will be randomly assigned to receive a foot bath or standard care. Researchers will measure pain levels and sleep quality using simpl…

This trial tests a non-transdermal biofield patch against a placebo patch in 40 adults who often feel anxious. Over 4 weeks, researchers will measure changes in anxiety, sleep quality, and energy levels. The goal is to see if the patch offers any real benefit beyond a placebo eff…

This study tests whether daridorexant, a recently FDA-approved sleep medication, can improve sleep quality and daytime alertness in smokers who struggle with insomnia during quit attempts. About 44 adult smokers who smoke at least 10 cigarettes daily will take the drug or a place…

This study looks at whether a device called TENS, which sends mild electrical pulses through the skin, can help reduce pain and improve sleep after inguinal hernia surgery. About 80 adults having this surgery will either receive TENS or standard care. Researchers will measure pai…

This early study tests a neck device that uses gentle suction to keep the airway open during sleep, which might help people with obstructive sleep apnea. Ten healthy volunteers will wear the device during one night of sleep and compare their breathing to a night without it. The g…

This study tests whether a relaxation method called autogenic training can help people on hemodialysis who suffer from restless leg syndrome, poor sleep, and fatigue. About 54 adults aged 45-55 will practice guided relaxation exercises for 8 weeks. Researchers will measure change…

This study tests whether a stellate ganglion block—a nerve block using the drug ropivacaine—given before surgery can improve sleep and recovery in 25 patients with prolonged disorders of consciousness after brain injury. Researchers will measure sleep time, brain oxygen levels, a…

This study tests whether a non-invasive device called TENS, placed on the neck, can improve sleep in postmenopausal women. Thirty-two women aged 50-65 with new sleep problems will receive the treatment. Researchers will measure changes in sleep quality and estradiol levels.

This study looks at whether doing moderate resistance exercises in the morning can improve sleep quality in young adults aged 18-35. Over 8 weeks, 64 participants with different sleep patterns (morning or evening types) will follow an online exercise program. Researchers will mea…

This study tests whether drinking a ketone supplement (Ketone-IQ) before sleep can improve sleep quality and reduce breathing pauses in people with moderate-to-severe obstructive sleep apnea. Thirty adults who already use CPAP will try the ketone drink for two nights and a placeb…

This study looks at whether teaching people with chronic neck pain better sleep habits, along with standard physiotherapy exercises, can improve their sleep quality and reduce disability. 120 adults aged 20-55 with poor sleep and neck pain lasting over 3 months will be split into…

This study tests whether a 4-week program combining ergonomic training with exercise can reduce pain, improve sleep quality, and lower anxiety in nursing students. Sixty participants will be randomly assigned to either the program or standard curriculum. The goal is to see if the…

This study looks at how stress from being a refugee—like trauma, discrimination, and adjusting to a new culture—affects sleep in Bhutanese refugees living in Ohio. Researchers will hold focus groups and interviews with 70 adults to understand their sleep problems and coping strat…

Researchers at the University of Houston are testing a forehead-worn device that records brain waves during sleep and plays brief, quiet pink-noise sounds timed to specific sleep stages. About 30 healthy adults aged 18 to 30 will use the system at home for up to 12 weeks and comp…

This study explores how the eyes' response to light relates to sleep patterns, circadian rhythms, and overall health. Researchers will measure pupil size under different lighting conditions and track sleep and melatonin levels in healthy volunteers and people with various medical…

This study looks at what happens when people who live above 2600 meters, in places like Quito, spend a week at sea level and then return to altitude. Researchers will measure sleep quality, oxygen levels during the night, and breathing patterns in healthy adults and in people wit…

Researchers are studying what happens when people with pulmonary arterial hypertension who live above 2600 meters spend a week at sea level. The trial compares their sleep, blood oxygen, and breathing during sleep at altitude and after seven days at sea level. It includes both pa…

Researchers at Massachusetts General Hospital are testing whether a single under-the-tongue dose of dexmedetomidine, a sedative, can safely alter sleep patterns, internal 24-hour rhythms, and daily cycles of a brain-aging protein in adults aged 65 and older. In this double-blind,…

This study aims to estimate how common tension-type headaches are among adults visiting outpatient clinics at Assiut University Hospitals, and to see if these headaches are linked to smartphone use, sleep quality, and quality of life. Researchers will assess around 199 adults age…

This trial tests whether a brief educational video about sleep can help college students sleep better and think more clearly. About 300 undergraduate students will be randomly assigned to watch the sleep lecture either right away or after a waiting period. Researchers will compar…

This trial tests whether a smartphone app and smartwatch can help Chinese, Malay, and Indian adults in Singapore improve their physical activity, sleep, and diet. Participants receive personalized digital nudges and complete surveys over 12 months. The goal is to see if these too…

This study tracks sleep quality in adults with obesity before and one year after metabolic surgery (gastric bypass or sleeve gastrectomy). Participants wear two sleep-monitoring devices for five nights at home and fill out sleep questionnaires and diaries. The goal is to see whet…

This study looks at how diet, physical activity, and sleep relate to body composition in women in Kazakhstan. About 200 women aged 20 and older will have a DEXA scan to measure fat, muscle, and bone density, and fill out questionnaires. The goal is to build a clearer picture of w…

This study looks at sleep health in people with HIV who are on different antiretroviral therapies. Some participants switch from a dolutegravir-based regimen to a doravirine-based one, while others stay on dolutegravir. Sleep is measured using questionnaires, wrist-worn activity …

This study develops and tests a digital sleep intervention called Nurturing Sleep for preschoolers (ages 3-5) living in foster care. Foster parents use a smartphone app to learn about sleep hygiene and receive tailored strategies based on their child's sleep challenges. The goal …

This study follows 100 new nurses over time, using non-invasive sleep monitors and questionnaires to track sleep quality, stress, and burnout. Researchers will use AI to see if sleep data can predict which nurses are at risk of burnout or leaving their jobs. No treatments are giv…

This study looks at whether sleep patterns—like duration, quality, and heart rate during sleep—are linked to how well stomach cancer responds to immunotherapy before surgery. Researchers will monitor sleep non-invasively in 120 patients with locally advanced gastric or gastroesop…

This observational study will test whether a 1-3 minute AI-powered facial scan can accurately measure vital signs like heart rate and blood pressure, as well as estimate blood sugar, cholesterol, and mental health status. Researchers will compare the scan results with standard me…

This study will test whether reducing recreational screen use to 1 hour per day for 4 weeks can improve mental well-being, sleep, and social interaction in 240 young people aged 13 to 24. Participants will either cut their screen time or continue as usual, and researchers will tr…

This pilot study tests a self-guided digital program called SOAR that shares science-backed sleep tips with people starting treatment for an eating disorder. The program includes videos on sleep hygiene and setting a regular sleep schedule. Researchers want to see if the program …

This study uses smartphone surveys to track the daily ups and downs of 300 parents in German-speaking Switzerland. Parents will answer quick questions about their mood, sleep, and activities five times a day for two weeks. The goal is to understand what makes parenting feel good …

This study tests whether a sleep education and hygiene program can improve sleep in young male soccer players aged 16-19. Fifty-two players from an academy will either receive sleep tips and access to their sleep data or continue as usual. Researchers will measure changes in slee…

This study looks back at data from 80 veterans and first responders who completed a 12-week program that combined mental health support, physical therapy, nutrition advice, and occupational therapy. Researchers want to see if the program helped improve sleep, anxiety, depression,…

This study will give 180 healthy adults a daily probiotic supplement (Lactobacillus plantarum) for 1 or 6 months. Researchers will collect blood and stool samples and run online cognitive tests to see if the supplement changes gut bacteria, blood markers, or thinking skills. The …

This study explores whether virtual reality (VR) construction tasks can detect changes in performance caused by lack of sleep. Researchers will enroll 12 participants and have them perform VR tasks after different sleep conditions. The goal is to see if VR can reliably measure sl…

This study tests a 12-week after-school active play program for primary school children in Bangladesh. The program includes free play and guided activities to boost physical activity, reduce sitting time, improve sleep, and build movement skills like running and jumping. About 35…

This study will ask 380 heart patients and healthcare workers at Assiut University Heart Hospital to fill out questionnaires about depression, anxiety, stress, and burnout. No treatments or changes are given—the goal is simply to find out how common these mental health problems a…

This study looks at whether low magnesium levels are linked to sleep problems in people with major depressive disorder. Researchers will measure magnesium in the blood of 90 adults and compare it to their sleep quality. The goal is to better understand this possible connection, n…

This study looks at whether giving different oxygen levels during rest breaks between short cycling exercises helps people with COPD feel less breathless and exercise more easily. Fifty adults with moderate COPD will do four short cycling sessions with rest in between. Researcher…

This study will check for stress, anxiety, depression, sleep problems, and bad breath in 110 adults with obesity who are getting ready for weight-loss surgery. Participants will fill out questionnaires and use a portable breath tester. The goal is to learn more about these issues…