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Nerve block before surgery may boost sleep and recovery in brain injury patients

NCT ID NCT07274683

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a stellate ganglion block—a nerve block using the drug ropivacaine—given before surgery can improve sleep and recovery in 25 patients with prolonged disorders of consciousness after brain injury. Researchers will measure sleep time, brain oxygen levels, and consciousness scores after the procedure. The goal is to see if this simple nerve block can help these patients sleep better and potentially aid their recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
stellate ganglion block with ropivacaine
What this could lead to
If it works, this could point toward a way to improve sleep and possibly aid consciousness recovery in patients with prolonged disorders of consciousness.
What could go wrong
This is a very small, early study with only 25 participants, so results may not apply broadly. The nerve block is given before surgery, and its effect on sleep or recovery may be minimal or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

pDOC Patients from Beijing Tian Tan Hospital

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18-65 years; * Prolonged disorders of consciousness after acquired brain injury; * Scheduled to undergo spinal cord electronic stimulator implantation under general anesthesia; * The skull is intact; * Informed consent is obtained; Exclusion Criteria: * Continuous sedation therapy is performed within 72 hours prior to the study; * The integrity of brain structure is disrupted due to causes such as open head injury and cerebral parenchymal resection; * Decreased intracranial compliance caused by hydrocephalus and other reasons; * Airway stenosis or severe dysfunction of ventilation or gas exchange due to various causes; * Known or suspected severe cardiac, pulmonary, and renal dysfunction; * History of sedative drug allergy; * Complicated by other mental or neurological disorders; * Local anesthetic allergy; * Other reasons for ineligibility in this study; * Informed consent is not obtained;

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Beijing Tian Tan Hospital

    Beijing, 100070, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.