Nerve block before surgery may boost sleep and recovery in brain injury patients
NCT ID NCT07274683
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a stellate ganglion block—a nerve block using the drug ropivacaine—given before surgery can improve sleep and recovery in 25 patients with prolonged disorders of consciousness after brain injury. Researchers will measure sleep time, brain oxygen levels, and consciousness scores after the procedure. The goal is to see if this simple nerve block can help these patients sleep better and potentially aid their recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- stellate ganglion block with ropivacaine
- What this could lead to
- If it works, this could point toward a way to improve sleep and possibly aid consciousness recovery in patients with prolonged disorders of consciousness.
- What could go wrong
- This is a very small, early study with only 25 participants, so results may not apply broadly. The nerve block is given before surgery, and its effect on sleep or recovery may be minimal or temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
pDOC Patients from Beijing Tian Tan Hospital
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18-65 years; * Prolonged disorders of consciousness after acquired brain injury; * Scheduled to undergo spinal cord electronic stimulator implantation under general anesthesia; * The skull is intact; * Informed consent is obtained; Exclusion Criteria: * Continuous sedation therapy is performed within 72 hours prior to the study; * The integrity of brain structure is disrupted due to causes such as open head injury and cerebral parenchymal resection; * Decreased intracranial compliance caused by hydrocephalus and other reasons; * Airway stenosis or severe dysfunction of ventilation or gas exchange due to various causes; * Known or suspected severe cardiac, pulmonary, and renal dysfunction; * History of sedative drug allergy; * Complicated by other mental or neurological disorders; * Local anesthetic allergy; * Other reasons for ineligibility in this study; * Informed consent is not obtained;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Tian Tan Hospital
Beijing, 100070, China
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Other studies related to the condition(s) this trial covers.
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