Sleep aid breakthrough: one drug during surgery may improve Post-Op rest
NCT ID NCT07550803
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a single dose of the steroid dexamethasone during nasal surgery can improve sleep quality on the first night after the operation. About 102 adults having nasal surgery under general anesthesia will be randomly assigned to receive either dexamethasone or a placebo. The main goal is to see if the drug leads to better sleep scores, as measured by a standard sleep questionnaire.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 102 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 19 years or older undergoing nasal surgery. Exclusion Criteria: * Patients who do not provide informed consent * Patients with neurological disease or cognitive impairment that may interfere with questionnaire completion * Patients with pre-existing sleep disorders or those taking sleep medications * Patients receiving chronic corticosteroid therapy * Known hypersensitivity to dexamethasone * Patients with glaucoma * Patients with poorly controlled diabetes mellitus (HbA1c \> 8.0%) * Patients with peptic ulcer disease * Pregnant or breastfeeding women * Patients deemed unsuitable for the study by the investigator (e.g., those requiring postoperative steroid administration for clinical reasons)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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