University Of Zurich

This study tested whether the drug acetazolamide (commonly used for altitude sickness) reduces pressure in the lung arteries differently in women compared to men when traveling to 3,600 meters. Over 300 healthy, non-smoking adults took either the drug or a placebo starting 24 hou…

This study tested whether the BCG vaccine, normally used to prevent tuberculosis, could reduce the hidden HIV reservoir in people living with HIV who are on antiretroviral therapy. Sixty participants received either a single BCG shot or a placebo. Researchers measured changes in …

This study looked at whether the drug acetazolamide (Diamox) prevents acute mountain sickness (AMS) equally well in women and men. Over 300 healthy adults traveled to high altitude and took either the drug or a placebo. The goal was to see if women, who may have higher drug level…

This study tested whether doing special breathing exercises before abdominal surgery could lower the number and severity of complications after the operation. 134 adults scheduled for major belly surgery took part. They practiced breathing with a device to strengthen their breath…

This study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were also getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than…

This study investigates whether a machine that analyzes exhaled breath can identify a unique chemical signature for lung cancer. Researchers will compare breath samples from people with lung cancer (before and after surgery) and healthy controls. The goal is to develop a non-inva…

This study tested whether advanced MRI scans can better determine how deeply bladder cancer has grown into the bladder wall. Accurate staging is crucial because it decides whether a patient needs just surgery or also chemotherapy and bladder removal. The study enrolled 186 people…

This study tested whether a simple home exercise program and protein supplements, alone or together, could help prevent falls in seniors at risk of muscle loss (sarcopenia). Over 800 older adults with early signs of frailty or a recent fall took part. They were assigned to do str…

This study tested whether a drug called acetazolamide can improve sleep-disordered breathing in women traveling to high altitude (3600 m). 303 healthy adults participated in a randomized, placebo-controlled trial. The main goal was to see if the drug reduced drops in oxygen level…

This study tested Pycnogenol, a natural pine bark extract, against a placebo in 153 adults with Long COVID. The goal was to see if it improves overall health and reduces symptoms like fatigue and brain fog. Participants took the supplement for 12 weeks and reported their health s…

This pilot study tested a short psychological program called Problem Management Plus (PM+) in 64 refugees and asylum seekers in Switzerland. The program, developed by the World Health Organization, uses simple techniques like problem-solving and stress management to reduce psycho…

This study tested whether combining mild electrical brain stimulation (tRNS) with white noise can temporarily reduce tinnitus symptoms. 35 adults with chronic tinnitus received either the combined treatment or brain stimulation alone. Researchers measured changes in tinnitus loud…

This study tested whether a more intense, precisely targeted type of radiation (SBRT) works better than standard radiation for reducing pain from cancer that has spread to the spine. About 219 adults with painful spinal metastases took part. The main goal was to see if SBRT leads…

This study looked at whether giving extra oxygen to people who live high in the mountains and have high altitude pulmonary hypertension (a type of high blood pressure in the lungs) helps them walk farther. Twenty-four participants completed the trial. Researchers measured how far…

This study tested whether people with pulmonary vascular disease (problems with blood vessels in the lungs) can walk the same distance in 6 minutes without extra oxygen as they can with it. 40 adults who had low oxygen levels during exercise did two walk tests—one breathing norma…

This study looked at whether people with chronic lung disease who experience drops in oxygen during exercise can walk just as far without extra oxygen as with it. Forty patients completed a 6-minute walk test twice: once breathing normal air and once with low-flow oxygen. The goa…

This study tested whether walking training overground with body weight support helps people with chronic spinal cord injury walk better. Fourteen participants were randomly assigned to either overground or treadmill training for four weeks. The goal was to see if the overground a…

This study looked at how sleeping at high altitude (3600 m) affects breathing in healthy women, and whether the phase of their menstrual cycle makes a difference. 91 women spent two nights at altitude while their oxygen levels and breathing patterns were measured. The goal was to…

This study looked at whether the phase of a woman's menstrual cycle affects her chances of getting acute mountain sickness (AMS) when traveling to high altitude. Researchers followed 91 healthy women as they spent two days at 3600 meters (about 11,800 feet). The goal was to see i…

This study looked at how men and women's brains and hearts react to mental stress. Researchers used special brain and heart scans on 64 healthy adults aged 50-75. The goal was to understand if stress affects heart health differently based on sex. No treatment was given; this was …

This study analyzed DNA from 9 patients with primary immune deficiencies whose genetic cause was unknown. Researchers used whole exome or genome sequencing to look for new mutations that might explain their condition. The goal was to identify new inborn errors of immunity, which …

This study looked at 70 people with idiopathic normal pressure hydrocephalus (iNPH), a condition that causes walking problems, memory loss, and bladder control issues. The goal was to find better ways to predict which patients would benefit from a surgery that drains extra fluid …

This study looked at whether chemicals in saliva can show when a driver is dangerously sleepy. Over 500 drivers stopped by police in Belgium gave a saliva sample and reported their sleepiness level. Researchers hope to find a biological marker that could one day be used to preven…

This study tested a new way to measure pain in preterm infants during a procedure called LISA, where surfactant is given to help them breathe. Researchers used skin conductance, which tracks nerve signals, and compared it to a standard pain scale. The goal was to see if this meth…

This study looked at 96 adults with house dust mite allergy to see if they also react to edible insects like crickets or mealworms. Participants had skin prick tests and their allergy history was reviewed. The goal was to understand patterns of insect sensitization, especially in…

This study tested whether digital intraoral scans are as accurate as traditional dental impressions for capturing full-arch teeth. Ten healthy adults received both conventional impressions and multiple digital scans. Researchers compared the scans to see how precise and true the …

This study looked at 24 people with high-altitude pulmonary hypertension who live above 2500 meters. Researchers measured their sleep breathing at 3200 meters and again after moving to 760 meters. The goal was to see if lower altitude improves oxygen levels and reduces breathing …

This study looked at 24 people with high altitude pulmonary hypertension who live above 8,200 feet. Researchers measured how far they could walk in 6 minutes at their home altitude (10,500 feet) and after moving to a lower altitude (2,500 feet). The goal was to see if relocating …

This study looked at 24 people with high altitude pulmonary hypertension (HAPH) who live above 2,500 meters. Researchers measured their lung blood pressure at 3,200 meters and then after moving to 760 meters for one night and seven nights. The goal was to see if simply being at a…

This study looked at how the X10D shoe sole affects walking in 15 healthy adults aged 50 to 65. Participants walked with the X10D sole, a neutral sole, and their own sports shoes. The goal was to measure changes in foot movement and walking patterns over 3-4 weeks. It is an early…

This study looked at 366 people who had a brain bleed from a burst aneurysm. Researchers measured hemoglobin in the fluid around the brain and spine to see if it could predict secondary brain injury, like artery spasms or lack of blood flow. The goal is to find a better way to mo…

This study tested whether a special type of MRI (multiparametric MRI) can reliably measure kidney function in people with metabolic syndrome—a cluster of conditions like obesity, high blood pressure, and high blood sugar. Researchers compared MRI results between 46 healthy volunt…

This study tested whether personalized walking training based on detailed 3D movement analysis works better than standard walking therapy. 63 people with spinal cord damage from injury or multiple sclerosis took part. The goal was to see if customizing exercises to each person's …

This study looked at whether giving extra oxygen can lower blood pressure in the lungs of people who live above 2500 meters and have high altitude pulmonary hypertension. Researchers measured heart changes with ultrasound in 48 highlanders while they breathed either oxygen or reg…

This study looked at nearly 500 people with stomach and bowel problems to see if a low-FODMAP diet helps reduce symptoms. Researchers also checked for joint hypermobility (very flexible joints) and how the gut microbiome might be linked. The goal is to better understand who benef…

This study tested whether drugs that boost serotonin—like psilocybin (magic mushrooms) and MDMA (ecstasy)—increase prosocial behavior compared to a dopamine-boosting drug (methylphenidate/Ritalin). 122 healthy adults received single doses and completed tasks measuring empathy, mo…

This study looked at whether using a gentle breathing support (noninvasive ventilation) during the placement of a breathing tube in newborns can make the procedure safer and more successful. Researchers observed 50 infants who needed a breathing tube in the delivery room or inten…

This study looked at 51 stable premature infants to see how their lung volume changes when placed in a car seat. Using a special imaging technique called electrical impedance tomography, researchers measured breathing patterns in three positions: lying flat, sitting in a car seat…

This study from the University of Zurich looked at how people with different neurological conditions walk. Researchers measured walking patterns in 208 adults, including those with stroke, Parkinson's, multiple sclerosis, and spinal cord injury, as well as healthy volunteers. The…

This study looks at how a robotic body-weight support system called FLOAT affects the way people with incomplete spinal cord injury perform everyday tasks like walking, standing up, and climbing stairs. Researchers measure movement and muscle activity with and without the robot's…