University Of Zurich

This study is testing a personalized approach to find better drug treatments for cancer that has spread to the brain (brain metastases). Researchers will take a small sample of a patient's tumor during surgery and quickly test many different drugs on it in the lab to see which on…

This study is testing whether playing gentle sounds during sleep to enhance deep sleep can slow the progression of brain changes in people with isolated REM sleep behavior disorder (iRBD) or early Parkinson's disease. Participants will wear a special headband and headphones at ni…

This study is testing a new, personalized way to plan radiation therapy for throat cancer. The goal is to shrink the area of healthy tissue that gets irradiated, aiming to reduce painful side effects like swallowing problems and taste loss, while still effectively treating the ca…

This study is testing whether a shorter, 5-week course of targeted radiation is safe and effective for men with prostate cancer who also have bothersome urinary symptoms or an enlarged prostate. It aims to see if this approach can control the cancer while keeping severe side effe…

This study is testing a new way to treat cat allergies called intralymphatic immunotherapy (ILIT). Instead of about 50 shots over 3 years, this method uses just 3-4 injections directly into a lymph node. Researchers want to see if this approach is safe and how it affects the immu…

This small pilot study is testing whether robot-assisted lung biopsies can be performed using moderate sedation with propofol, a common sedative, instead of deeper anesthesia. Researchers want to see if this approach still allows doctors to accurately reach and sample suspicious …

This Swiss study is testing if a gentle, non-invasive electrical stimulation applied to the ankle can prevent serious bladder damage in people who have recently suffered a spinal cord injury. About 114 participants will be randomly assigned to receive either the real stimulation …

This study is testing two common at-home treatments—a heat pad and a massage gun—to see which one better relaxes a stiff jaw muscle. Researchers will measure muscle tightness in 40 healthy volunteers using a special ultrasound scan before and after each treatment. The goal is to …

This study is testing a cream called ruxolitinib to see if it can safely and effectively treat skin rashes that develop as a side effect of a common cancer immunotherapy (anti-PD1). The cream is already approved for other skin conditions. Researchers will enroll about 20 adult pa…

This study is testing whether a new counseling program is practical to run for people with COPD. The program focuses on helping patients manage the emotional distress that often comes after a serious worsening of their lung symptoms. About 20 hospitalized patients will receive te…

This study aims to understand why severe nerve pain develops after a spinal cord injury. Researchers will measure pain signals and nervous system responses in 300 participants, including people with recent or long-term injuries and healthy volunteers. The goal is to learn how the…

This study aims to understand why some people with eczema and related allergies like asthma and food allergies go into remission while others do not. Researchers will follow 1,000 participants, including healthy people, over time to collect health and lifestyle data. The goal is …

This study aims to see if simple health checks before advanced cancer treatments can predict severe side effects in patients aged 65 and older. Researchers will test mobility, memory, and self-care skills in 208 older adults scheduled for CAR-T cell or bispecific antibody therapy…

This study aims to understand how a specific, ancient part of the brain helps control movement and how it might adapt to help recovery after a spinal cord injury. Researchers will observe 248 people, including both healthy volunteers and those with recent or long-standing spinal …

This study aims to understand how the brain and spinal cord change their structure and function after a spinal cord injury. Researchers will use MRI scans to compare 450 people with recent or long-term injuries to healthy volunteers. The goal is to find patterns in these brain ch…

This study aims to understand how the brain and spinal cord change their structure and function after someone has a stroke. Researchers will use MRI scans to compare 35 stroke survivors with healthy people, looking for patterns that relate to a person's symptoms and recovery. The…

This large European study aims to understand how people naturally recover from spinal cord injuries. Researchers will follow 8,000 patients through rehabilitation, measuring their independence, movement, and nerve function. The data will create a detailed picture of recovery to h…

This study is testing a new, detailed tool called the INTeRCePT assay to see if it can predict which patients with a type of blood cancer (lymphoma) will respond well to a treatment called CAR-T cell therapy. The study will enroll 50 adults with lymphoma who are already scheduled…

This study aims to understand how the brain changes its structure and function in people who were born without a hand. Researchers will use MRI brain scans and behavioral tests to compare adults with this condition to healthy volunteers. The goal is to learn how early life experi…

This study uses a powerful 7 Tesla MRI scanner to take detailed pictures of the brain in people with migraine, drug-resistant epilepsy, or visual snow syndrome. Researchers want to see how the brain's structure and activity differ in these conditions compared to healthy volunteer…

This study aims to understand how spinal cord injuries change the structure and fluid flow around the spinal cord. Researchers will use MRI scans on 350 adults with cervical injuries and compare them to healthy people. The goal is to link these physical changes to a person's symp…

This study aims to understand how synchronized breathing support helps premature infants' lungs work better. Researchers will use a special imaging belt to measure lung volume changes in 27 preterm babies receiving breathing assistance. The goal is to learn why synchronized suppo…

This study aims to understand how the brain and spinal cord change their structure and function after a spinal cord injury. Researchers will use advanced MRI scans and other tests on 225 participants with recent or long-term injuries to create detailed maps of nerve activity and …