University Of Zurich

This trial studies nearly 1,000 people with severe aortic stenosis and blocked coronary arteries who need both a valve replacement (TAVI) and artery stenting (PCI). Researchers want to see if doing the stenting before or after the valve replacement leads to fewer deaths, heart at…

This study tests a new therapy for preterm babies born before 32 weeks who show abnormal general movements, a sign of possible developmental problems like cerebral palsy. The therapy involves gently guiding the baby's stiff or cramped movements into more normal, fluid patterns. R…

This early-phase study tests a new way to give immunotherapy drugs (nivolumab and ipilimumab) for patients with lung cancer or melanoma that has spread to the lining of the brain and spinal cord (leptomeningeal metastases). The drugs are given both directly into the spinal fluid …

This study compares a new technique that combines cone-beam CT scans with a robotic bronchoscope against standard methods for taking lung tissue samples. The goal is to see if the new approach can diagnose lung cancer and other lung diseases more accurately. About 300 adults who …

This study tests whether removing the fallopian tubes during planned gallbladder removal surgery is safe for women aged 45 and older. The goal is to see if this extra step can help prevent ovarian cancer without causing more complications. About 300 women will take part, with hal…

This study tests a new nurse-led counselling program designed to help people with stable COPD manage emotional distress. Fifteen outpatients will receive ten counselling sessions over three months. The main goal is to see if the program is feasible, not to prove it works. Researc…

This study tests a new counseling program designed to help people with COPD cope with emotional distress during a sudden worsening of their condition. Twenty adults hospitalized for a COPD flare-up will receive ten counseling sessions with a specialized nurse over three months. T…

This study tests whether a cream containing ruxolitinib can improve skin rashes caused by anti-PD1 cancer immunotherapy. About 22 adults with this type of rash will use the cream for 12 weeks. The goal is to see if the rash clears by at least 90%.

This study tests whether a new method of radiation therapy, which uses an MRI scan to plan treatment and a CT scan to deliver it, is feasible for treating pelvic lymph node metastases. Twenty adults with confirmed cancer spread to pelvic lymph nodes will receive stereotactic body…

This study aims to see how prostate tumors change on MRI scans shortly after a precise type of radiation therapy (SBRT). Researchers will compare these MRI changes with PSA levels in the blood. The study involves 28 men with localized prostate cancer and is designed to improve un…

This study aimed to see if advanced MRI techniques could better detect endometriosis compared to standard ultrasound or laparoscopy. It was designed for patients already scheduled for an MRI. However, the study was withdrawn before enrolling anyone, so no data or conclusions are …