University Of Zurich

This trial is testing whether adding the antidepressant drug vortioxetine to standard brain cancer treatment helps patients live longer without their cancer worsening. The drug was identified through lab tests showing it might fight brain cancer cells. The study will enroll 78 ad…

This small pilot study is testing if a fecal microbiota transplant (FMT) can change the gut bacteria of people who have both type 2 diabetes and stable coronary artery disease. Researchers want to see if altering the gut microbiome can improve metabolic health and reduce inflamma…

This study is testing if a new flexible cable (SuperCable) is better than traditional steel wires for closing the breastbone after heart bypass surgery. Researchers want to see if the cable helps the bone heal faster, reduces pain after surgery, shortens hospital stays, and impro…

This study is testing a new way to deliver precise radiation therapy to men with prostate cancer who have had both hips replaced. Hip implants can create blurry areas on medical scans, making it hard for doctors to see the prostate clearly for treatment planning. Researchers will…

This study is testing whether improving deep sleep with gentle sounds can make brain training more effective for people with Parkinson's disease who have mild memory problems. Fifty participants will do a 5-week brain fitness program at home and wear a special headband at night; …

This study is testing a personalized approach to find treatments for brain tumors that have stopped responding to standard therapies. Doctors will test tumor cells from surgery in a lab to see which drugs might work best for each patient. The goal is to see if this 'drug-matching…

This study is testing whether a new MRI contrast agent called gadopiclenol can detect brain metastases earlier than current standard methods. Researchers will enroll 180 patients with advanced lung cancer, breast cancer, or melanoma who are at high risk of cancer spreading to the…

This study is testing a smartphone app designed to help people with depression feel less lonely and more supported while they wait to start therapy. For 21 days, the app will send different types of encouraging prompts to 120 participants, asking them to reach out for social supp…

This study aims to understand if common food processing methods, like heating or extraction, change how likely soy is to trigger an allergic reaction. Researchers will first test processed soy in a lab, then perform skin prick tests on up to 55 adults with and without soy allergi…

This study aims to understand if the body's response to phosphate—a mineral common in many foods—changes as people age and differs between men and women. Researchers will give a phosphate drink to 40 healthy volunteers from two age groups (young adults and older adults) and measu…

This study aims to deeply understand heart failure by analyzing the molecular details of 500 patients. Researchers will combine detailed health information with advanced lab tests on blood and tissue samples to find patterns linked to the disease. The goal is to discover clues th…