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Weekly adaptive radiation aims to sharply target High-Risk prostate cancer

NCT ID NCT07591051

Not yet recruiting Disease control Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a weekly, image-guided radiation therapy (SBRT) for men with very high-risk prostate cancer that may have spread to nearby lymph nodes. The treatment uses weekly CT or MRI scans to adapt the radiation dose precisely to the tumor. The main goals are to see if this approach is feasible and safe, with 54 participants being followed for side effects and cancer control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stereotactic body radiation therapy (SBRT) guided by CT or MRI scans
What this could lead to
If successful, this could offer a more precise and effective radiation treatment for men with very high-risk prostate cancer that has spread to nearby lymph nodes.
What could go wrong
This is a small, early feasibility study (54 people) testing a new way of delivering an established treatment. It may not prove better than standard approaches, and there is a risk of side effects like urinary or bowel problems.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Clinic Heidelberg

    Heidelberg, Baden-Würtemberg, 69120, Germany

    Contact

  • University Hospital Zurich

    Zurich, Canton of Zurich, 8091, Switzerland

    Contact

    Contact

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