Heart study seeks best order for two common procedures

NCT ID NCT04310046

Ongoing Disease control Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 32 times

Summary

This study looks at nearly 1,000 people with severe aortic stenosis (a narrowed heart valve) and blocked heart arteries. It compares doing artery stenting before versus after valve replacement to see which order is safer and more effective. The goal is to reduce death, heart attacks, repeat procedures, and major bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Academic Teaching Hospital of the Friedrich-Alexander-University Erlangen-Nuremberg

Fürth, Germany
Arnault Tzanck Institute Saint Laurent du Var

Nice, France
Azienda Santa Croce e Carle

Cuneo, Italy
Campus Kerckhoff of the Justus Liebig University Giessen

Bad Nauheim, Germany
Cardiology Department Azienda Ospedaliera Ordine Mauriziano di Torino

Turin, Italy
Cardiology Department, CHU Timone Marseille

Marseille, France
Cardiovascular Center Bad Neustadt/Saale

Bad Neustadt an der Saale, Germany
Geneva University Hospitals

Geneva, Switzerland
German Heart Center of Charité

Berlin, Germany
Heart Center Leipzig at University of Leipzig

Leipzig, Germany
Heart and Vascular Centre Bad Bevensen

Bad Bevensen, Germany
Heinrich-Heine University

Düsseldorf, Germany
Helios Hospital Erfurt

Erfurt, Germany
Helios Hospital Pforzheim

Pforzheim, Germany
Herzzentrum Dresden

Dresden, Germany
IRCCS Azienda Ospedaliera Metropolitana

Genova, Italy
Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT)

Palermo, Italy
Justus-Liebig University of Giessen

Giessen, Germany
Klinikum Fulda

Fulda, Germany
Klinikum Ingolstadt

Ingolstadt, Germany
Klinikum Klagenfurt am Wörthersee

Klagenfurt, Austria
Krankenhaus der Barmherzigen Brüder

Trier, Germany
LMU Munich

Munich, Germany
Lausanne University Hospital

Lausanne, Switzerland
Leiden University Medical Center

Leiden, Netherlands
Municipial Hospital Karlsruhe

Karlsruhe, Germany
Otto-von-Guericke University Magdeburg

Magdeburg, Germany
Prosper Hospital

Recklinghausen, Germany
Schüchtermann-Clinic Bad Rothenfelde

Bad Rothenfelde, Germany
Segeberger Kliniken GmbH

Bad Segeberg, Germany
TUM University Hospital

Munich, Germany
The Clinique de l'Infirmerie Protestante

Lyon, France
Thoraxcenter, Erasmus MC

Rotterdam, Netherlands
Toulouse University Hospital

Toulouse, France
Ulm University Heart Center

Ulm, Germany
University Heart and Vascular Centre Hamburg

Hamburg, Germany
University Hospital Basel

Basel, Switzerland
University Hospital Bergmannsheil

Bochum, Germany
University Hospital Dijon

Dijon, France
University Hospital Erlangen

Erlangen, Germany
University Hospital Jena

Jena, Germany
University Hospital Regensburg

Regensburg, Germany
University Hospital Schleswig-Holstein

Kiel, Germany
University Hospital Zürich, Cardiology Department

Zurich, 8091, Switzerland
University of Oldenburg

Oldenburg, Germany
Universitäts-Herzzentrum Freiburg Bad Krozingen, Freiburg & Bad Krozingen

Bad Krozingen, Germany
Universitätsklinikum Frankfurt

Frankfurt, Germany
Zentralklinik Bad Berka

Bad Berka, Germany

Conditions

Explore the condition pages connected to this study.

AORTIC STENOSIS CORONARY ARTERY DISEASE PCI TAVI