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Smarter radiation: could less be more for throat cancer patients?

NCT ID NCT06563362

Recruiting now Disease control Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving less radiation to healthy lymph nodes can reduce side effects for people with oropharynx cancer. The approach uses a computer model to personalize which lymph nodes need treatment. The trial will enroll 120 patients and track if cancer returns in untreated areas over 2-3 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy
What this could lead to
If successful, this could lead to a standard way to reduce radiation side effects for oropharynx cancer patients without increasing the risk of cancer returning.
What could go wrong
This is a phase 2 trial with only 120 participants, so results are preliminary. The main risk is that reducing radiation might allow cancer to spread to untreated lymph nodes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms oropharynx cancer oropharynx squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OROPHARYNX CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cantonal Hospital Aarau

    RECRUITING

    Aarau, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpitaux universitaires de Genève

    RECRUITING

    Geneva, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inselspital Bern

    RECRUITING

    Bern, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Regionale di Bellinzona

    RECRUITING

    Bellinzona, Switzerland

    Contact

  • Réseau Hospitalier Neuchâtelois

    RECRUITING

    Neuchâtel, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zurich University Hospital

    RECRUITING

    Zurich, Canton of Zurich, 8091, Switzerland

    Contact

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