New study uses electrical imaging to peek inside lungs of premature babies on breathing machines

NCT ID NCT07237139

Recruiting now Knowledge-focused Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will use a special imaging technique called electrical impedance tomography (EIT) to see how lung volume changes in premature babies who are on a type of breathing support called synchronized noninvasive positive pressure ventilation (sNIPPV). Researchers want to understand why sNIPPV works better than other methods. The study will include 27 preterm infants born before 30 weeks and on sNIPPV, measuring their lung activity at five different times.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could explain why synchronized ventilation helps preterm babies breathe better, potentially improving how doctors use this therapy.
What could go wrong: This is a small, early observational study with only 27 infants, so results may not apply to all preterm babies. It measures lung changes but does not test a new treatment.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia Premature Birth Pulmonary Atelectasis respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LUNG DISEASE OF NEWBORN INFANT, PRETERM LUNG VOLUME RESPIRATORY DISTRESS SYNDROME (NEONATAL) RESPIRATORY SUPPORT SYNCHRONIZED NONINVASIVE POSITIVE PRESSURE VENTILATION (SNIPPV)

Contacts and locations

Locations

University Hospital Zurich
RECRUITING

Zurich, Canton of Zurich, 8091, Switzerland

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