New adaptive radiation aims to spare bladder in prostate cancer patients

NCT ID NCT06834152

Recruiting now Disease control Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This study is testing a new type of radiation therapy that adapts to changes in the prostate and bladder during each treatment session. It is for men with localized prostate cancer who also have an enlarged prostate or urinary symptoms. The goal is to see if this approach can reduce severe urinary side effects while still controlling the cancer. The trial will enroll 75 participants across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy (adaptive stereotactic body radiotherapy)
What this could lead to: If successful, this approach could offer a safer, more precise radiation option for prostate cancer patients with urinary issues, reducing severe side effects.
What could go wrong: This is a small, early-phase study (75 participants) focused on safety and feasibility. The treatment may still cause significant urinary or bowel side effects, and it is not yet proven to be better than standard radiation.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma benign prostatic hyperplasia Lower Urinary Tract Symptoms prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALIZED PROSTATE CARCINOMA LOWER URINARY TRACK SYMPTOMS PROSTATE CANCER (ADENOCARCINOMA) PROSTATE HYPERPLASIA

Contacts and locations

Locations

Klinik für Radioonkologie und Strahlentherapie, Universitätsklinikum Heidelberg
NOT_YET_RECRUITING

Heidelberg, Baden-Wurttemberg, 69120, Germany
Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum LMU
NOT_YET_RECRUITING

Munich, Bavaria, 81377, Germany
University Hospital Zurich, Department of Radio-Oncology
RECRUITING

Zurich, Canton of Zurich, 8090, Switzerland

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