Cat allergy treatment gets a needle upgrade: fewer shots, same hope

NCT ID NCT06960382

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new method for treating cat allergies called intralymphatic immunotherapy (ILIT), where allergen extracts are injected directly into a lymph node. Thirty-six adults with cat-triggered allergic rhinitis and asthma will receive 3-4 ultrasound-guided injections. The goal is to see if this approach is safe and well-tolerated compared to standard allergy shots.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ALUTARD SQ Felis domesticus (cat hair allergen extract)
What this could lead to
If successful, this could lead to a faster, safer way to treat cat allergies with fewer injections than current methods.
What could go wrong
This is an early-phase trial with only 36 participants, so results may not apply to everyone. There is a risk of allergic reactions, including anaphylaxis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed consent as documented by signature. * Cat-dander-induced ARC as confirmed by patient history and type-1-sensitization to cat dander in skin and/or serum. Exclusion Criteria: * Hypersensitivity to phenol. * Planned depot steroid injection for treatment of ARC * Patients with uncontrolled asthma or FEV1 \< 70% of the predicted value in adults (after adequate pharmacological therapy). * Patients with a severe asthma exacerbation in the past 3 months. * Irreversible secondary changes in the affected organ (e.g., emphysema, bronchiectasis). * Chronic obstructive or restrictive lung disease. * Patients with active systemic autoimmune diseases and patients with immune deficiencies or immune weaknesses. * Severe chronic inflammatory diseases. * Concomitant infection with fever or other signs/symptoms of an acute or chronic infection at treatment visit. * Chronic obstructive or restrictive lung disease * Patients with malignant tumours that currently have clinical significance. * Disease or conditions rendering the treatment of anaphylactic reactions difficult (symptomatic coronary heart diseases, severe arterial hypertension, and treatment with beta-blockers). * Known cardiovascular disease, i.e., not even NYHA class I. * Use of ACE-blockers. * Recent or on-going hepatic or renal disease. * Severe chronic renal insufficiency (due to aluminium burden). * Alcohol or drug abuse * Women who are pregnant and breast feeding * Women of childbearing age who wish to become pregnant or do not use contraception. * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant. * Participation in another study with investigational drug within the 30 days preceding and during the present study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • University Hospital Zurich

    RECRUITING

    Zurich, 8091, Switzerland

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