University Of Wisconsin, Madison

This study is testing the safety and initial effects of a special lung treatment given to extremely premature infants who are still on a breathing machine at 7-14 days old. The treatment combines surfactant, a substance that helps lungs stay open, with a steroid called budesonide…

This study is testing a new combination of two drugs, ASTX727 (a pill) and retifanlimab (an IV infusion), for people with advanced Merkel cell carcinoma, a rare and aggressive skin cancer. It is specifically for patients whose cancer has continued to grow or spread despite receiv…

This study aims to see if giving an extra dose of caffeine helps improve oxygen levels in the kidneys of very premature babies. It will involve about 102 babies born before 30 weeks. Researchers want to find out if this extra dose can reduce kidney injury without harming the baby…

This early-stage trial is testing a modified stem cell transplant for children and young adults with serious, non-cancerous blood diseases like sickle cell anemia and bone marrow failure syndromes. The goal is to make the transplant safer by using a new method to filter the donor…

This study will test whether adding a special education and coaching program to regular Special Olympics activities helps adults with intellectual and developmental disabilities get better healthcare. Researchers will compare the new program against standard Special Olympics heal…

This study aims to find the most effective way to help Black adults quit smoking long-term. Researchers will compare three different support programs: standard quitline services, a more intensive culturally tailored program, and that same intensive program with financial incentiv…

This study is testing a text and web-based support tool designed for a person with opioid addiction and a close family member or friend. The goal is to see if this digital tool helps the person start medication treatment for their addiction and stick with it longer. Researchers w…

This study aims to see if a free mindfulness and well-being smartphone app is practical, safe, and shows early signs of helping adults who have recently had suicidal thoughts. About 50 participants will use the app for 4 weeks, completing lessons and brief surveys. The goal is to…

This small pilot study is testing whether a mobile phone app can effectively deliver depression treatment. Eight African American adults with depression will attend six weekly 90-minute mental health classes through the app and complete regular surveys. The goal is to see if this…

This study is testing if a simple communication strategy can help children with cerebral palsy speak more clearly. Kids ages 7-17 will learn to point to letters or pictures on a board while they talk, which may give listeners helpful clues. Researchers will measure if this one-ti…

This study aims to find the best way to add support to a meditation app to help people with depression and anxiety. About 688 participants will use the Healthy Minds Program app and be randomly assigned to receive different combinations of coaching, email support, or encouraging …

This study is testing whether a new AI tool can reduce the heavy paperwork burden on nurses. The software listens to conversations between nurses and patients and automatically drafts parts of the patient's digital chart. Researchers will measure if this saves nurses time on docu…

This study is testing a new type of X-ray machine designed to take clearer pictures during image-guided medical procedures. Researchers will compare images from the new machine to those from standard machines to see if the new technology improves image quality. The study will not…

This study aims to understand why psilocybin, the psychedelic compound in 'magic mushrooms,' might improve a person's mood and sense of well-being. Researchers will enroll 120 adults to test whether the benefits come from the conscious psychedelic experience or from direct effect…

This study aims to understand if a new dairy ingredient is as good a source of choline as eggs for post-menopausal women. Researchers will compare how the body absorbs and uses choline from a whey protein supplement versus whole egg powder. Participants will drink chocolate-flavo…

This study aims to understand if learning about well-being through a meditation app can positively impact individuals and their romantic relationships. Researchers will enroll 2,000 couples where one partner experiences symptoms of depression. One partner will use the app while t…

This study is testing a small device that attaches to a shoe to monitor walking patterns. Researchers want to see if it accurately measures how healthy adults aged 65 and older walk on flat ground and stairs. The goal is to gather information to improve the device's design for fu…

This study aims to understand how often and why common cold viruses (rhinoviruses) cause severe breathing problems that require children to be hospitalized. Researchers will follow healthy children in the community and compare them to children who are hospitalized with severe res…

This study aims to understand how learning your Alzheimer's disease biomarker test results affects your emotional well-being, daily behaviors, and future health decisions. Researchers will follow 240 adults aged 50+ who are at risk for Alzheimer's and have completed brain scans. …

This early-stage study is testing whether a drug called apalutamide, which is used for prostate cancer, affects a specific protein (EGFR) in bladder cancer cells. Researchers want to see if blocking male hormones influences this protein, which is linked to cancer progression. The…

This early-phase study aims to understand how metabolic syndrome (a cluster of conditions like high blood pressure and high blood sugar) reduces blood flow to the brain, and whether this effect is stronger in women than in men. Researchers will compare 72 healthy adults to adults…

This study aims to see if taking an oral probiotic supplement is safe and practical for people who have early Alzheimer's disease or are at risk for it. Researchers will enroll 40 participants, some with mild memory problems and some without, to take the supplement for up to a ye…

This study is testing new computer software designed to improve MRI brain scans. Researchers want to see if the software can make scans faster, reduce noise, improve image quality, and make the process easier for both patients and technicians. About 131 adults will have one 60-mi…