Mirror-Image meth: scientists compare two forms of the drug

NCT ID NCT06746831

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 4 times

Summary

This study will give 17 healthy adults three different versions of methamphetamine to see how the body processes each one. Meth comes in two mirror-image forms: S-meth, a strong stimulant used for ADHD, and R-meth, a weaker form found in some nasal sprays. Researchers will measure drug levels in blood, urine, and saliva, and test thinking skills after each dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
S-(+)-methamphetamine and R-(-)-methamphetamine
What this could lead to
If successful, this could help understand how different forms of methamphetamine affect people, potentially informing safer use or new treatments.
What could go wrong
This is a very small, early-stage study in healthy volunteers, not patients. It measures drug effects in a lab setting, so results may not apply to real-world use or lead to any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Wisconsin

    Madison, Wisconsin, 53705, United States