Mind zapping: can targeted electrical pulses tune the brain?
NCT ID NCT07752745
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This study explores whether a non-invasive technique called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity in healthy adults. Using MRI scans to personalize electrode placement, participants will receive different types of stimulation while their brain waves are recorded with high-density EEG. The goal is to understand how varying the strength and frequency of the electrical pulses affects the brain, which could inform future therapeutic uses.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcranial electrical stimulation with temporal interference (TES-TI) using high-density EEG
- What this could lead to
- If successful, this could help refine non-invasive brain stimulation techniques, potentially leading to new treatments for neurological conditions without surgery.
- What could go wrong
- This is an early-stage mechanistic study with a small number of healthy participants. It aims to understand basic effects, not to prove clinical benefit, and results may not translate to patient populations.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Wisconsin - Madison
Madison, Wisconsin, 53706, United States