University Of California, Davis

This early-phase trial tested a combination of two drugs, ibrutinib and lenalidomide, in 4 adults with myelodysplastic syndrome (MDS) who had not responded to or could not tolerate standard treatments. The main goal was to find the safest dose and identify side effects. While the…

This study tested a combination of two drugs, ibrutinib and blinatumomab, in 19 adults with B-cell acute lymphoblastic leukemia that had returned or stopped responding to treatment. The goal was to see how well the drugs worked together to stop cancer growth. The study is complet…

This early-stage trial tested a combination of two drugs—enzalutamide (a standard hormone therapy) and niclosamide (a drug used for worm infections)—in 6 men with advanced prostate cancer that no longer responds to hormone therapy. The goal was to find the safest dose and identif…

This study tested whether a gentle suction device placed in the throat could reduce the amount of food or liquid that accidentally enters the airway during swallowing. The study involved one person with severe swallowing problems who relied on a feeding tube and had not improved …

This study tested whether a special adhesive device called Embrace helps surgical scars heal better. Twelve adults who had skin surgery had part of their wound treated with the device and part left untreated. Researchers compared the appearance and width of the scar in both areas…

This study looked at whether qigong, a gentle mind-body practice, could improve the health and well-being of people with long COVID. Forty adults with symptoms lasting over 12 weeks took part in in-person qigong sessions in Sacramento. The goal was to see if it was feasible and i…

This study looked at whether a new method using blood pressure readings can measure heart contraction strength as well as the standard ultrasound method during heart surgery. 43 adults having planned heart surgery took part. The goal was to see if the simpler blood pressure metho…

This study tested whether text messages encouraging smokers to call a quitline would increase enrollment. Over 4,000 adults who smoked but had not received help to quit were sent texts offering either free counseling or free nicotine patches. The goal was to see which offer led m…

This study looked at whether eating two types of sweet oranges—one rich in certain pigments (Rosy Red Valencia) and one without them (Olinda Valencia)—affects markers of inflammation and oxidative stress in healthy adults. Twenty participants ate one of the two orange varieties d…

This study tested a program for older adults (ages 65-90) who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if the program was feasible a…

This study measured how much lidocaine, a common pain reliever, reaches the tumor and blood in 12 adults undergoing surgery for glioblastoma. The goal was to understand how lidocaine behaves in the body during surgery. The information gathered may help researchers develop new tre…

This study looked at how different ventilator settings (like breath size and pressure) change the pressure inside the lungs and chest during surgery. Researchers used a small balloon placed in the esophagus to measure these pressures in 150 adults having planned surgery. The goal…

This study looked at whether a personalized, home-based exercise program could improve muscle function in people with moderate-to-severe chronic kidney disease (CKD) who are not on dialysis. 32 participants were randomly assigned to either an exercise group (combining strength an…

This study used advanced total-body PET scans to compare lung function in 13 people who had COVID-19 and healthy volunteers. The goal was to see how the virus changes the lungs' air-blood barrier. Participants were scanned within 8 weeks of diagnosis and again 4 months later to t…

This study tested whether a disposable attachment called Endocuff Vision helps doctors find more precancerous polyps (sessile serrated adenomas) during routine colon cancer screening. Over 400 adults getting a screening colonoscopy were randomly assigned to either a standard colo…

This study tested whether eating certain dietary fats can trigger gut bacteria to produce special fats called cyclopropane fatty acids (CpFAs), which may help regulate blood sugar and liver health. Ten healthy adults ate specific fats, and researchers measured CpFA levels in thei…

This study looked at whether placing stitches 1 centimeter apart or 2 centimeters apart leads to a better-looking scar after skin surgery on the body or arms and legs. Fifty adults had their wounds closed with both spacing methods on different parts of the same wound. Blinded rev…

This study looked at how different supplements affect collagen production in the body after exercise. Twenty healthy adults took vitamin C enriched hydrolyzed collagen, whey protein, or a placebo before doing short jump rope sessions three times in 24 hours. Researchers measured …

This study looked at whether protein from insects (IPC80 and whole buffalo powder) can turn on muscle-building processes as well as whey protein. Twenty healthy adults drank a single dose of one of these proteins, and researchers measured how their blood affected muscle cells in …

This study tested a new type of PET scan to see if it could detect whether targeted therapy for genitourinary cancer (like kidney cancer) is working within days or weeks, instead of months. Eleven patients were scanned before and shortly after starting treatment. The goal was to …

This study used a new, advanced total-body PET/CT scanner to collect health information from 20 healthy volunteers who are part of racial or ethnic minority groups. The goal was to gather baseline data on how the body processes a sugar tracer, which could help improve future medi…

This early study tested a new PET/CT imaging agent in 5 adults who had recovered from COVID-19. The goal was to see if the tracer could detect lung damage caused by the virus. Participants had no prior lung disease and needed two negative COVID tests before each scan. The study w…

This study looked at how drinking orange juice compared to a sugary drink affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugar-sweetened beverage for four weeks. Researchers measured changes in cholesterol, blood sugar …

This study looked at whether using telemedicine (video or phone calls) helps people with hard-to-heal leg wounds in rural areas see a specialist faster than going in person. About 116 adults with leg ulcers from conditions like diabetes or poor blood flow took part. Researchers m…

This study used a special full-body PET scanner to watch how a radioactive sugar moves through head and neck cancer and radiation-caused inflammation over time. Seven adults with stage II-IVa oral cancer took part after completing radiation therapy. The goal was to learn more abo…