New drug combo shows promise for tough leukemia cases
NCT ID NCT02997761
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested a combination of two drugs, ibrutinib and blinatumomab, in 19 adults with B-cell acute lymphoblastic leukemia that had come back or wasn't responding to treatment. The goal was to see how many patients achieved complete remission. The study is completed, and results will help determine if this approach is worth further study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ibrutinib and blinatumomab
- What this could lead to
- If it works, this combination could offer a new treatment option for patients whose leukemia has returned or stopped responding to standard therapy.
- What could go wrong
- This is a small, early-phase trial with only 19 participants, so results may not apply to everyone. Side effects from the drugs can be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
USC/Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
-
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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