University Of California, Davis

This study tests whether a set of strategies to improve coordination between emergency departments and outpatient clinics helps people with opioid use disorder stay on buprenorphine longer. About 3,500 adults who start buprenorphine in the ER will be followed for up to 12 months.…

This study tests two ways to deliver antibiotics directly into the breast pocket during tissue expander breast reconstruction to prevent infections. About 100 women will be randomly assigned to receive either a non-absorbable disc or an absorbable bead that releases antibiotics. …

This study looks at whether a simple vaginal swab test, called ROM-Plus, can quickly sort patients with pregnancy of unknown location and vaginal bleeding into high or low risk for ectopic pregnancy. About 122 English-speaking adults who are stable and have this condition will ta…

This study compares two needle devices used to take tissue samples from pancreatic lesions during an endoscopic ultrasound. The goal is to see which device provides better quality samples for diagnosis with fewer needle sticks. About 30 adults with pancreatic lesions will be rand…

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can help mothers of premature or sick babies produce more breast milk while their infant is in the NICU. About 40 mothers will receive either the supplement or a placebo for several weeks. T…

This study tests a special sleeve worn on the lower belly that uses body heat to release energy waves and negative ions, aiming to increase blood flow and reduce pain and inflammation. Researchers will compare the sleeve to a placebo in 100 women aged 18-45 who have regular perio…

This pilot study tests a new, less invasive way to repair hernias using ultrasound and a needle to place stitches through the skin, avoiding large cuts and general anesthesia. It is for adults with small hernias who cannot or choose not to have standard surgery. About 30 particip…

This study looks at whether acupuncture can reduce pain and improve daily function in people with chronic low back pain caused by myofascial pain syndrome (muscle knots). Sixty-four adults will receive either real or sham acupuncture for eight weeks. Researchers will use full-bod…

This study aims to see if 5 days of accelerated brain stimulation (called iTBS) can quickly reduce depression symptoms in adults. Participants will receive either real or sham (fake) stimulation over 50 sessions in 5 days. Researchers will track mood changes, brain scans, and bio…

This study looks at ways to make knee steroid injections less painful for people with knee osteoarthritis. Researchers will test if using a smaller needle or a cooling spray (ethyl chloride) before the shot reduces pain. About 88 adults will rate their pain right after the inject…

This study looks at whether a medicine called timolol, usually used for glaucoma, can help surgical wounds heal faster when applied as a gel. About 220 adults who have had skin cancer removal surgery will either use timolol or a standard hydrogel on their wound every day for 12 w…

This study tests a mobile health program called FANS-EI that aims to help caregivers of young autistic children stay engaged in early interventions. Researchers will measure caregiver comfort, participation, and feelings of support. The study involves 28 caregiver-child pairs and…

This study tests whether a sensitive blood test (ctDNA) can help doctors decide the best treatment for people with early-stage rectal cancer. About 200 adults will be enrolled to see if using the blood test leads to better outcomes, like complete tumor disappearance or longer sur…

This study tests whether a mobile app that uses AI and game-like features can help young adults (ages 18-24) who sometimes struggle to afford food make healthier eating choices. About 114 UC Davis students will use either a basic food-tracking app or one with extra nudges and rew…