University Of California, Davis

This study is a long-term registry for people who received the experimental drug iltamiocel in a previous study for tongue swallowing problems caused by head and neck cancer treatment. The goal is to monitor safety and see if the drug continues to help with swallowing over time. …

This study compares two types of antibiotic carriers placed during tissue expander breast reconstruction to lower infection risk. About 100 women will receive either absorbable antibiotic beads or a non-absorbable disc, both releasing vancomycin and tobramycin. Researchers will m…

This study compares two needle devices used to take tissue samples from pancreatic lesions during an endoscopic ultrasound. The goal is to see which device provides better quality tissue for diagnosis with fewer needle sticks. About 30 adults with pancreatic solid lesions larger …

This study looks at whether a simple vaginal swab test, called ROM-Plus, can quickly tell if a pregnancy of unknown location (PUL) with vaginal bleeding is high or low risk for ectopic pregnancy. About 122 English-speaking, stable patients will provide a swab during their first v…

This study tests whether adding a medication called 5-fluorouracil to a standard steroid treatment helps improve thick, raised burn scars more than the steroid alone. Both treatments are delivered through tiny holes made by a CO2 laser, which helps the medications reach deeper in…

This pilot study compares two forms of goji berry powder—whole berry and juice powder—in women aged 40 to 65 who have frequent hot flashes. Participants eat one mug cake made with their assigned powder daily for 30 days and track their symptoms on a smartphone. The study looks at…

This study looks at ways to reduce pain during knee steroid injections for osteoarthritis. Researchers will test if using a thinner needle or a numbing spray (ethyl chloride) makes the injection hurt less. 88 adults with knee osteoarthritis will rate their pain right after the sh…

This study tests a wearable sleeve with semiconductors that claim to boost blood flow and reduce pain. One hundred women with painful periods will wear either the active sleeve or a placebo version. The goal is to see if the sleeve can ease cramping and improve quality of life wi…

This study tests whether 5 days of accelerated transcranial magnetic stimulation (TMS) can quickly reduce depression symptoms. 264 adults with major depressive disorder will receive either real or sham stimulation, along with brain scans and mood tracking. The goal is to see if t…

This study tests a new way to fix hernias using a needle guided by ultrasound, avoiding large cuts and general anesthesia. It is for adults who cannot or do not want standard surgery. About 30 people will be followed for 8 months to see if the procedure is safe and improves quali…

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can help mothers of premature or sick babies in the NICU produce more breast milk. About 40 mothers will receive either the supplement or a placebo for several weeks. The goal is to see if t…

This study tests whether a topical timolol solution, normally used as eye drops, can help skin wounds heal faster when left open after surgery. 220 adults who choose to let their surgical wounds heal naturally will apply either timolol or a placebo gel daily for 12 weeks. Researc…

This study tests a mobile health program called FANS-EI that aims to support caregivers of young autistic children in staying engaged with early interventions. Researchers will measure caregiver comfort, participation, and sense of support. The study involves 28 caregiver-child p…

This pilot study tests a new imaging method called PET-enabled dual-energy CT to measure bone and soft tissue in the bone marrow. It will include 45 adults: some with multiple myeloma scheduled for CAR T-cell therapy and some healthy volunteers. The goal is to see if this new met…

This study tests whether a smartphone app that uses artificial intelligence to send gentle reminders can help young adults (ages 18–24) who struggle with food insecurity make better food choices. About 114 UC Davis students will use either a basic app that tracks what they eat or…

This phase 2 trial tests whether a highly sensitive blood test (ctDNA) can help manage treatment for 200 people with early-stage rectal cancer. After standard chemotherapy and radiation, some patients will have their treatment guided by the blood test results instead of immediate…