Laser opens door to better burn scar treatment

NCT ID NCT07660120

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether adding a medication called 5-fluorouracil to a standard steroid treatment helps improve thick, raised burn scars more than the steroid alone. Both treatments are delivered through tiny holes made by a CO2 laser, which helps the medications reach deeper into the scar. Each participant's scar is split in half, with one side receiving both drugs and the other side only the steroid, allowing a direct comparison. The goal is to see if the combination reduces scar thickness and stiffness better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

triamcinolone acetonide and 5-fluorouracil

What this could lead to

If adding 5-FU works better, it could offer a less painful, more effective way to treat thick burn scars.

What could go wrong

This is a small, early-stage study. The added medication may not improve results and could cause side effects like skin irritation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

burn Cicatrix, Hypertrophic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••