Could a common vitamin speed burn recovery?
NCT ID NCT01749371
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This trial investigates whether high-dose vitamin E (alpha-tocopherol) can reduce oxidative stress and improve outcomes in adults with severe burns covering at least 40% of their body. Participants receive vitamin E drops after surgery, and researchers measure vitamin levels, lung function, and markers of healing. The goal is to see if this simple supplement can lessen complications like lung injury and slow wound healing, potentially shortening hospital stays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- vitamin E (alpha-tocopherol) given as oral drops
- What this could lead to
- If it works, this could lead to a simple, safe vitamin supplement that helps burn patients heal faster and spend less time in the hospital.
- What could go wrong
- This is a small, early-phase trial with only 27 participants, so results may not apply to all burn patients. High-dose vitamin E slightly increases bleeding risk.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Hermann Hospital Burn Intensive Care Unit
Houston, Texas, 77030, United States
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University of Texas Medical Branch: Blocker Burn Unit and Shriners Hospitals for Children
Galveston, Texas, 77555, United States
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University of Texas Southwestern Medical Center, Parkland Health and Hospital System
Dallas, Texas, 75390, United States
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