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Collagen supplements put to the test: which one boosts Body's own collagen best?

NCT ID NCT05427279

Knowledge-focused Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different collagen supplements with vitamin C affect collagen production after exercise. Twenty healthy adults took either hydrolyzed collagen, a vegan collagen (PrimaColl), whey protein, or a placebo before doing short jump rope sessions three times in 24 hours. Researchers measured a marker of collagen synthesis in the blood to compare the supplements' effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hydrolyzed collagen, PrimaColl (vegan collagen), whey protein, or placebo (maltodextrin) each with 50 mg vitamin C
What this could lead to
If successful, this could help clarify which supplement best supports collagen production after exercise, potentially guiding nutrition advice for joint and tissue health.
What could go wrong
This is a very small, early-stage study with only 20 healthy participants. Results may not apply to older adults or people with injuries. The collagen synthesis is measured indirectly, so real-world benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Oct 2022

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * healthy active male or female * normal weight (BMI between 18 and 25 kg/m2) Exclusion Criteria: * taking any medication that may interfere with the study * have a history of more than 3 musculoskeletal injuries within the past 12 months * have any health or dietary restriction that would be affected by the supplementation protocol

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Effect of food supplement

Contacts and locations

Locations

  • Hickey Laboratory

    Davis, California, 95616, United States

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