Old drug, new hope: niclosamide combo tackles tough prostate cancer

NCT ID NCT03123978

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tested the safety and best dose of adding niclosamide (a drug used for tapeworm infections) to standard hormone therapy (enzalutamide) in 6 men with advanced prostate cancer that no longer responds to hormone treatment. The goal was to see if the combination could be given safely and help control the cancer. The study was completed but did not involve a cure; patients continued on ongoing treatment.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States