The Hong Kong Polytechnic University

This pilot trial tests whether a 4-week group education program that blends Chinese medicine concepts—like body constitution, dietary therapy, and acupressure—with standard diabetes self-management training is feasible and acceptable for adults with type 2 diabetes in Hong Kong. …

This pilot study tests whether combining a gentle brain stimulation technique called tDCS with aerobic exercise can improve cognitive functions like memory and attention in people with schizophrenia. Participants will be randomly assigned to receive either the combined treatment …

This trial tests whether a parent-child physical activity program can increase exercise levels in children aged 9–18 with leukemia who are on maintenance therapy. Children and parents attend weekly exercise sessions together for three months. The study compares this approach to c…

This study tests whether oral dietary supplements can improve the health of the back of the eye in children with nearsightedness (myopia). About 156 children aged 8-13 will take either a supplement or a placebo for a period, and researchers will measure changes in the thickness a…

This study tests whether a 10-week digital mindfulness program, combined with dietary advice, can help people with type 2 diabetes and obesity lose weight and improve blood sugar control. Participants learn mindful eating techniques through videos and home exercises. The trial me…

This study tests two types of daily disposable contact lenses designed to slow the progression of myopia (nearsightedness) in children aged 7 to 12. Over two years, 126 Hong Kong Chinese children will wear either a special lens or a standard single-vision lens, with their eyes me…

This study tests two types of modified spectacle lenses designed to slow the progression of myopia (nearsightedness) in children aged 6 to 13. Over one year, researchers will measure changes in the back of the eye (choroid), eye length, and prescription strength. The goal is to s…

This study tests whether a 6-week self-management program, done with a caregiver's help, can improve diabetes control and thinking skills in adults aged 55+ who have both diabetes and mild cognitive impairment. About 309 participants will attend weekly group sessions and provide …

This study tests whether a 6-week telephone-based therapy called acceptance and commitment therapy (ACT) can help young adults aged 18-35 who drink heavily to quit or reduce drinking. About 288 participants will be randomly assigned to receive either ACT or a supportive phone cal…

This study tests a new, non-invasive treatment for dry age-related macular degeneration (AMD), a common cause of vision loss in older adults. About 94 people aged 50 and older with dry AMD will use a red-light device at home twice daily for three months. Researchers will check if…

This trial tests a program called OUTDOOR-FIT, designed to help mildly frail older adults become more physically active. Participants attend weekly workshops, use senior-friendly outdoor exercise equipment, and get support from volunteers and a mobile app. The goal is to see if t…

This study focuses on middle-aged and older spousal caregivers, who often face high stress and health decline. Researchers are developing a tool to predict frailty risk and testing a virtual social robot that guides caregivers through 20-minute sessions three times a week for six…

This study tests whether an enhanced version of the Intensive Diabetes Prevention Program (IDPP) works better than the standard program at recruiting and keeping participants in district health centres. Researchers will compare the two approaches in 170 adults with prediabetes, l…

This pilot trial tests whether a chatbot powered by large language models can help adolescent and young adult cancer survivors address reproductive concerns. Participants will be randomly assigned to use the chatbot or read an electronic brochure with similar information. The stu…

This study aims to develop and pilot a digital version of Acceptance and Commitment Therapy (ACT) specifically for suicide prevention in Chinese-speaking adults. Researchers are working with people who have experienced suicidal thoughts to design the program, then testing whether…

This trial tests whether a web-based, game-like training program can strengthen the connection between the ears and the brain in older adults with mild-to-moderate hearing loss. Over 12 weeks, participants complete listening and thinking exercises designed to improve speech under…

This trial tests whether a six-week personalized behavioral sleep program, called ISleepFAST, can improve sleep and daily functioning in adults who have had a stroke and still struggle with sleep or circadian problems. Forty participants will be randomly assigned to either the sl…

This study tests a mobile app designed to encourage physical activity in adolescents aged 12-18 who have completed treatment for blood cancers like leukemia or lymphoma. Thirty participants will either use the app or receive usual care. The main goal is to see if a larger study i…

This trial tests a smartphone app called E-breathing that detects when a teen is feeling distressed and prompts them to practice slow-paced breathing. The study includes 100 adolescents aged 11 to 17 in Hong Kong who have at least mild symptoms of depression, anxiety, or stress. …

This study tests whether a simple breathing exercise—inhaling against resistance using a handheld device—can reduce knee pain in people aged 55 and older with knee osteoarthritis. Participants will do the exercises at home for 8 weeks, with gradually increasing resistance. The tr…

This study tests whether a simple, low-cost sleep hygiene education program can improve insomnia as effectively as a standard cognitive behavioral therapy app. About 264 adults with insomnia will be randomly assigned to the education program, the app, or a control group. The goal…

This study tests a 4-week AI chatbot program called AI-EGG that teaches emotional skills to young and middle-aged colorectal cancer survivors. The goal is to see if it helps them build resilience and improve quality of life. Fifty-four participants will be randomly assigned to ei…

This study tests if a phone-based therapy called Acceptance and Commitment Therapy (ACT) can help young adults aged 18-35 who drink heavily to quit or reduce alcohol use. Participants will receive weekly phone sessions for 6 weeks and track their drinking. The study compares ACT …

This study tests whether an artificial intelligence (AI)-guided sleep program is practical and well-liked by adults aged 60 and older who have both insomnia and mild memory concerns. Researchers will enroll 60 participants to check how many people join, stick with the program, an…

This study tests a structured sleep hygiene education program for adults with insomnia. Ten Hong Kong Chinese participants will learn behavior-change techniques to improve their sleep. The goal is to see if this low-cost, non-drug approach is feasible and effective for reducing i…

This study tests whether a social robot named KaKa can reduce depressive symptoms in family caregivers of people with dementia. 148 caregivers will either use the robot at home for 6 weeks or receive weekly reading materials. The robot is designed to boost inner strength and copi…

This study is testing a new AI chatbot designed to answer questions from people with sarcoma, a type of cancer. The chatbot will be available 24/7 by voice or text for one month. Researchers want to see if using the chatbot helps patients feel more satisfied with the information …

This study tests whether a combination of gentle brain stimulation and visual exercises can improve vision and daily function in people with glaucoma who have lost some side vision. About 56 adults with open-angle glaucoma will receive both real and sham treatments in a crossover…

This study looks at whether a therapy called Acceptance and Commitment Therapy (ACT) can help fathers of children with special needs feel more flexible in their thinking and improve their mental health. About 50 fathers will take part, with half getting ACT and the other half rec…

This pilot study tests whether pulsed electromagnetic field (PEMF) therapy can reduce pain and improve function in people with inflammatory knee osteoarthritis. Fifty participants will receive either active PEMF or a sham treatment twice a week for 8 weeks. The study measures pai…

This study tests whether using a heart rate sensor to personalize home exercise can reduce pain and improve daily function better than a standard exercise program. About 240 adults aged 45+ with mild-to-moderate knee osteoarthritis will follow a 12-week program, with follow-up at…

This study tests a death education program for family caregivers of people with advanced cancer. The program includes four one-on-one sessions to help caregivers communicate about death, reduce anxiety and depression, and improve spiritual well-being. About 30 caregivers will tak…

This study tests if a gentle, non-invasive electrical stimulation on specific acupoints can reduce nerve pain caused by chemotherapy in children aged 10-17 with acute lymphoblastic leukemia. The treatment is given for 8 weeks, and researchers will check if it helps with pain, mov…

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can improve walking in people with Parkinson's disease. 81 participants with mild to moderate Parkinson's who have trouble starting to walk will receive …

This study tests whether virtual reality (VR) hypnosis can improve sleep in Chinese teens who have survived cancer. 186 participants will be randomly assigned to VR hypnosis, cognitive behavioral therapy for insomnia (CBT-I), or VR relaxation. The goal is to see if VR hypnosis is…

This study tests whether gentle electrical stimulation on acupoints or acupressure on the ear can reduce nerve pain caused by chemotherapy in children with leukemia. 132 children aged 8-17 will be randomly assigned to one of three groups: electrical stimulation, acupressure, or s…

This study tests a 12-week nurse-led program for childhood cancer survivors aged 13-18 and their parents. The program includes face-to-face and online sessions to help manage symptoms, improve self-care, and connect families with other health professionals. Sixty-eight families w…

This pilot study tests a tool called CSNAT-I that helps healthcare workers identify and address the needs of family caregivers looking after palliative cancer patients at home. Sixty caregivers in Hong Kong will be randomly assigned to receive the tool or usual care. The study wi…

This study is testing a new, investigational eye scanner that uses light waves to measure the eye before cataract surgery. Researchers want to see if its measurements match those of a standard device, and whether an artificial intelligence model can better predict the correct len…

This observational study looks at whether adults' sleep quality, sleep timing, and natural chronotype (morning vs. evening preference) are linked to how they share resources with others. Participants fill out sleep questionnaires, keep a 7-day sleep diary, and play a brief comput…

This observational study aims to understand why individuals perceive colours and visual rivalry differently. Researchers will test 128 adults using computer-based tasks to measure colour perception and binocular rivalry (when each eye sees a different image). They will also explo…

This study aims to create a therapy program using Acceptance and Commitment Therapy (ACT) for fathers of children with special needs in Hong Kong. Researchers will interview 20 fathers and social workers to understand their challenges and what kind of support would help. The goal…

This study tests an AI tool called EyeAgent that helps eye doctors make decisions. About 300 people visiting eye clinics in Hong Kong and mainland China will take part. The AI reviews patient images and history to suggest diagnoses and treatments. The goal is to see if using the …

This study aims to measure how the two sides of the brain communicate after a stroke using a safe, non-invasive technique called transcranial magnetic stimulation (TMS) combined with EEG and EMG. Researchers will test a new way to temporarily adjust these brain signals in 20 stro…

This study tests a smartphone app that sends personalized happiness exercises to college students when they are feeling down. Researchers will compare the app to other methods to see if it improves well-being, happiness, and life satisfaction. The study involves 354 healthy colle…