Tanabe Pharma Corporation

This study tested a new combination vaccine called BK1310, designed to protect infants against five serious diseases: tetanus, diphtheria, whooping cough (pertussis), polio, and Hib meningitis. Researchers compared it to giving two separate, already-approved vaccines. The goal wa…

This study tested a new combination vaccine called BK1310 in healthy infants. The goal was to see if it safely protects against five serious childhood diseases: Hib, diphtheria, pertussis (whooping cough), tetanus, and polio. Researchers compared BK1310 to existing vaccines to me…

This study tested a new vaccine called MT-2301 to protect healthy infants from Haemophilus influenzae type b (Hib), a bacteria that can cause serious infections like meningitis. The study involved 154 infants between 2 and 7 months old and compared the new vaccine to an existing …

This study tested a booster vaccine for adolescents to strengthen protection against diphtheria, tetanus, and whooping cough (pertussis). It involved 446 healthy 11- and 12-year-olds who had received their childhood DTaP shots. Researchers compared the new booster to an older vac…

This study tested a new combination vaccine called BK1310 in healthy infants. The goal was to see if it was safe and effective at protecting babies against several serious diseases, including Hib, diphtheria, pertussis (whooping cough), tetanus, and polio. Researchers measured th…

This study aimed to collect real-world information on how well the drug argatroban works for treating a serious condition called heparin-induced thrombocytopenia (HIT) Type II. HIT is a dangerous reaction to the blood thinner heparin that causes low platelets and a high risk of b…

This study tested whether a drug called MP-424 could help people with a specific type of chronic hepatitis C. Fifteen patients with genotype 1b hepatitis C who hadn't taken certain other medications received the treatment. Researchers checked if the virus remained undetectable si…

This study compared two drugs, Edaravone and Sodium Ozagrel, to see which one helped people recover better after a sudden stroke. It involved 401 adults who received treatment within 24 hours of their stroke. The main goal was to see how many patients had minimal or no disability…

This study tested whether adding an experimental drug called MP-424 to two standard hepatitis C medications could better control the virus. It involved 54 adults with a specific type of hepatitis C who had never been treated or whose previous treatment had stopped working. The ma…

This study tested how well a drug called MP-513 controls blood sugar levels throughout the day in people with type 2 diabetes. Japanese adults with diabetes took the drug for 4 weeks while researchers measured their blood sugar responses to meals. The goal was to see if this medi…

This study tested the long-term safety of MCI-196, a medication that helps control high phosphorus levels in people with advanced kidney disease who are on dialysis. The research followed 632 patients for up to one year to monitor how well they tolerated the medication and whethe…

This study tested if a new drug called MT-6548 works as well as a standard treatment (darbepoetin alfa) for anemia in people with chronic kidney disease who are on dialysis. It involved 323 participants in Japan who were already receiving treatment for their anemia. The main goal…

This completed Phase 3 trial tested whether adding an experimental drug (MP-424) to two standard hepatitis C medications could better control the virus. It involved 189 adults with a specific strain of hepatitis C who had never received treatment before. The main goal was to see …

This study tested a new medication called MP-214 for people with schizophrenia. It involved 38 participants and lasted 12 weeks. The main goals were to see how the drug moves through the body, check its safety, and measure if it helps control symptoms.

This study tested the long-term safety and effectiveness of adding canagliflozin (a pill) to insulin therapy for Japanese adults with type 2 diabetes. The 139 participants had already completed a 16-week study and took the medication for an additional 36 weeks. Researchers measur…

This study tested a medication called TA-650 in children with moderate to severe Crohn's disease. The goal was to see if regular injections could reduce disease activity and control symptoms. Researchers measured changes in a disease activity score and monitored safety in 14 pedi…

This study tested whether adding an experimental drug called MP-424 to two standard Hepatitis C medications could help patients whose previous treatments didn't work. It involved 32 adults with a specific type of Hepatitis C (Genotype 1) who had not responded to earlier therapy. …

This study tested a new oral medication called TA-7284 for people with type 2 diabetes. Researchers followed nearly 1,300 Japanese patients for one year to see how safe and effective the medication was, either alone or combined with other diabetes drugs. The goal was to help cont…

This study tested a medication called TA-650 in children with moderate to severe ulcerative colitis, a painful bowel disease. The goal was to see if the drug could help control the disease and reduce symptoms like stomach pain and bloody stools. Twenty-one children received the d…

This study tested whether a drug called MCI-186 could help control the progression of ALS (Lou Gehrig's disease). It involved 25 people with moderate ALS who received either the drug or a placebo through daily IV infusions for 24 weeks. Researchers measured changes in physical fu…

This study tested whether adding a pill called canagliflozin to insulin therapy helps control blood sugar better in adults with type 2 diabetes. It involved 146 Japanese patients whose blood sugar was still too high despite using insulin, diet, and exercise. Participants took eit…

This study tested a new drug called MT-6548 for treating anemia (low red blood cells) in people with chronic kidney disease who are not on dialysis. It compared the new drug to an existing standard treatment to see if it works just as well and is safe over a long period. The goal…

This study tested a drug called MT-6548 for people on kidney dialysis who have anemia (low red blood cells). The goal was to see if the drug could safely raise and keep hemoglobin levels in a healthy range. It involved 24 participants in Japan who were not using other common anem…

This was a very small, early-stage study to gather initial information on a potential new drug called MT-2990 for ANCA-associated vasculitis (AAV), a rare autoimmune disease. It involved only 5 patients with active AAV. The main goal was to explore the drug's safety, how it works…

This study tested whether adding a new drug called MP-513 to the common diabetes medication metformin could help control blood sugar levels better. It involved 448 adults with type 2 diabetes who were already taking metformin. Researchers compared four different doses of MP-513 o…

This study tested whether a daily medication called MT-5199 could safely reduce the involuntary movements of tardive dyskinesia. Researchers enrolled 256 adults with moderate to severe symptoms who also had conditions like schizophrenia or bipolar disorder. Participants received …

This study aimed to check the long-term safety and effectiveness of the diabetes drug Teneligliptin (MP-513) over one year. It involved 240 Japanese adults with type 2 diabetes, who took the drug either by itself or alongside another common diabetes medication. Researchers tracke…

This large, completed Phase 3 trial tested whether the drug MCI-196 could help control two common problems in people with kidney failure on dialysis: high phosphorus and high 'bad' cholesterol. The study involved 642 stable dialysis patients who were randomly assigned to receive …

This study tested whether adding an experimental drug called MP-424 to two standard hepatitis C medications could help patients whose infection returned after previous treatment. The trial involved 109 people with a specific type of hepatitis C who had relapsed. Researchers measu…

This large, completed Phase 3 trial tested whether adding a charcoal-based medication called AST-120 to standard care could slow the worsening of moderate to severe chronic kidney disease (CKD). The study involved over 1,000 adults and aimed to see if the treatment could delay th…

This early-stage study tested the safety of a new drug called MP-424 when given alongside two standard hepatitis C medications. It involved 20 patients with a specific type of chronic hepatitis C. The main goal was to see how the body processes the new drug and to check for any s…

This study followed patients who completed earlier trials of oral edaravone for ALS to monitor long-term safety. Fifteen participants in Japan took the medication in cycles until it became commercially available or until August 2023. The main goal was to track side effects and ad…

This study tested a new diabetes medication called Teneligliptin (MP-513) to see if it safely lowers blood sugar levels in Japanese adults with type 2 diabetes. Over 300 participants took either the drug or a placebo pill daily for 12 weeks. The main goal was to measure changes i…

This study tested whether a three-drug combination (MP-424, interferon beta, and ribavirin) could successfully control Hepatitis C virus in people with specific strains of the disease. It involved 74 patients who were either new to treatment or had tried previous interferon-based…

This study tested the safety and effectiveness of adding the drug canagliflozin to existing GLP-1 therapy for one year in Japanese adults with type 2 diabetes. It involved 71 participants whose blood sugar was not well controlled on their current treatment. The goal was to see if…

This study tested whether adding a new drug called MP-424 to two standard hepatitis C medications could help patients who had previously relapsed after treatment. The trial involved 108 people with a specific type of hepatitis C (genotype 2) who had seen their infection return af…

This Phase 3 study tested whether the drug MCI-186 could help control ALS symptoms and slow disease progression. 206 people with ALS received either the drug or a placebo through daily IV drips for 24 weeks. Researchers measured changes in physical function, breathing ability, an…

This study tested whether long-term, repeated treatment with the drug edaravone (MCI-186) could help control the progression of ALS, a severe nerve disease. It involved 181 patients who had already completed a prior 24-week trial. Researchers measured changes in patients' ability…

This study tested whether adding a new drug called Teneligliptin to an existing diabetes medication (pioglitazone) could better control blood sugar in Japanese adults with type 2 diabetes. It involved 204 participants who took the drug combination for up to 52 weeks. The main goa…

This study tested whether the drug teneligliptin helps control blood sugar in adults with type 2 diabetes. 254 Chinese participants were randomly assigned to receive either the drug or a placebo pill for 24 weeks while continuing their usual diet and exercise. Researchers measure…

This study tested whether a drug called MCI-186 (now known as edaravone) could slow the worsening of ALS symptoms. It involved 137 people with early-stage ALS who could still manage daily activities independently. For 24 weeks, participants received either the drug or a placebo t…

This study aimed to test the long-term safety and effectiveness of an investigational drug called MP-214 for people with schizophrenia. It involved 42 participants who were already taking one or more other antipsychotic medications. The main goal was to see how well patients tole…

This study tested whether the diabetes medication canagliflozin could slow the progression of kidney disease in people with diabetes. It involved 308 Japanese patients who already had signs of kidney damage and were taking standard blood pressure medications. Researchers compared…

This study tested whether giving higher doses of the drug infliximab (TA-650) could better control rheumatoid arthritis in patients who were still experiencing symptoms despite taking methotrexate. Over 300 participants received one of three different maintenance doses after init…

This study tested a drug called MT-6548 to see if it could safely and effectively treat anemia (low red blood cells) in people with chronic kidney disease who use peritoneal dialysis. It involved 42 participants in Japan who were either starting anemia treatment or switching from…

This study tested whether an experimental drug called MCI-196 could help control type 2 diabetes. For 12 weeks, 183 adults with elevated blood sugar took either the drug or a placebo pill, and neither they nor their doctors knew which one. Researchers measured changes in blood su…

This study tested if adding a new drug called Teneligliptin (MP-513) to an existing Sulfonylurea medication was safe and effective for controlling blood sugar in Japanese adults with type 2 diabetes. It involved 194 participants and measured changes in key blood sugar markers ove…

This study tested a new oral medication called TA-7284 for people with type 2 diabetes whose blood sugar wasn't well controlled by diet and exercise alone. For 12 weeks, 383 participants took either the new drug or a placebo (a pill with no medicine) to see if it safely lowered b…

This study tested whether adding a pill called teneligliptin to insulin therapy helps control blood sugar better in Japanese adults with type 2 diabetes. It involved 148 participants who were already on a stable insulin dose. Researchers measured changes in key blood sugar marker…

This large study tested whether adding AST-120 to standard care could slow the worsening of moderate to severe chronic kidney disease. Over 1,000 patients were randomly assigned to receive either AST-120 or a placebo pill, and researchers tracked whether they needed dialysis, a k…

This study tested a second treatment option for children with Kawasaki disease who did not get better after the standard first therapy. It compared a new drug called TA-650 against an existing control drug to see which was better at reducing fever and preventing heart complicatio…

This study tested whether a medication called MP-214 could help control symptoms in people experiencing a schizophrenia flare-up. Researchers compared the drug against a placebo in 512 patients over 6 weeks to see if it reduced symptoms and was safe to use. The trial measured cha…

This study tested a new oral medication called MP-214 to see if it is safe and effective for people with schizophrenia. Thirty-four participants took one of three different doses of the pill daily for two weeks. The main goals were to check for side effects and to see how the dru…

This study tested a drug called TA-650 in 18 people with severe, hard-to-treat Behcet's disease. The goal was to see if regular infusions could make the disease's serious symptoms disappear and reduce inflammation. Researchers measured improvements in ulcers, brain lesions, and b…

This study tested whether the drug MCI-196 could safely control high phosphorus levels in people with kidney failure on dialysis. Researchers compared the drug against a placebo in 336 patients over 16 weeks. The goal was to see if the drug could effectively manage this common an…

This study tested the long-term safety and effectiveness of the drug Teneligliptin (MP-513) for managing type 2 diabetes. It involved 462 Japanese patients who took the drug alone or alongside their usual diabetes pills for 52 weeks. The main goal was to see how safe the drug was…

This study tested whether a drug called MCI-196 could safely and effectively control high phosphorus levels in the blood of adults with kidney failure who are on dialysis. After a 12-week period where all participants received the drug, some were randomly switched to a placebo (d…

This study tested the safety and effectiveness of giving two diabetes drugs together for a full year. It involved 153 Japanese adults with type 2 diabetes whose blood sugar was not well controlled on one of the drugs alone. Researchers measured side effects, changes in long-term …

This study tested whether adding the drug canagliflozin to an existing medication (teneligliptin) could help Japanese adults with type 2 diabetes who still had high blood sugar. For 24 weeks, researchers measured changes in long-term blood sugar levels (HbA1c), body weight, and o…

This study tested whether adding a new drug called MP-424 to two standard hepatitis C medications could help patients who didn't respond to prior treatment. It involved 10 people with a specific type of hepatitis C (genotype 2) that had resisted earlier therapy. The goal was to s…

This study aimed to see if a medication called MP-214 is safe and effective for long-term use in people with chronic schizophrenia or elderly patients with schizophrenia. It involved 125 participants who were either in the chronic phase of the illness or between 65 and 74 years o…

This study tested whether adding an experimental drug called MP-435 to a standard medication (methotrexate) could better control rheumatoid arthritis symptoms. It involved 112 adults whose arthritis was not fully controlled by methotrexate alone. For 12 weeks, participants receiv…

This early-stage study tested a new diabetes medication called TA-7284 to check its safety and how it affects blood sugar levels. Researchers gave the drug to 61 people with type 2 diabetes for 15 days, testing four different doses. The main goal was to see how the body processes…

This study tested whether adding a drug called teneligliptin to an existing drug, canagliflozin, could help Japanese adults with type 2 diabetes who still had high blood sugar. It involved 154 participants who took the two-drug combination once a day for 24 weeks. The main goal w…

This study tested if a blood thinner called argatroban is as safe and effective as the standard heparin for patients undergoing a planned procedure to open a blocked heart artery (stent placement). It involved 140 patients with stable heart disease or a certain type of chest pain…

This study tested a lower dose of a clot-dissolving drug called alteplase for Japanese patients who had a stroke caused by a blocked blood vessel in the brain. The goal was to see if this lower dose could safely help patients recover more function after their stroke. The drug had…

This study aimed to check the long-term safety and effectiveness of an investigational medication called MP-214 for people with schizophrenia. It included 254 patients who had already finished a related earlier study. The main goal was to monitor for any side effects and see how …

This study tested whether doubling the dose of the medication TA-650 could help patients with Crohn's disease who weren't getting enough relief from the standard dose. It involved 39 adults whose symptoms returned despite regular treatment. Researchers measured changes in disease…

This study tested if a new drug called MCI-196 could lower bad cholesterol (LDL) in people with severe kidney disease who are on dialysis. It compared MCI-196 to a common cholesterol drug (simvastatin) and to a placebo (a dummy pill). The goal was to see if the new drug worked as…

This study tested if adding a new drug called teneligliptin to the standard metformin treatment helps control blood sugar better in adults with type 2 diabetes. It involved 247 Chinese patients whose diabetes was not well-controlled on metformin alone. For 24 weeks, researchers c…

This study tested a new oral medication called TA-7284 to see if it could help control blood sugar in adults with type 2 diabetes. For 24 weeks, 272 Japanese participants whose diabetes wasn't well-managed by diet and exercise alone received either a low dose, high dose, or a pla…

This study tested the long-term safety and effectiveness of a drug called MCI-196 for people on dialysis who have high phosphate levels in their blood. It involved 116 adult patients on stable dialysis treatment. The main goal was to see how safe the drug was over a year, while a…

This study aimed to confirm the real-world safety and effectiveness of the clot-dissolving drug alteplase for patients having an acute ischemic stroke. It involved 58 patients who received the drug within 3 hours of stroke symptoms starting. Researchers measured how well the drug…

This study tested whether doubling the dose of the drug TA-650 could help patients with moderate-to-severe psoriasis who initially responded to a standard dose but later saw their symptoms return. The trial involved 51 adults with different forms of psoriasis, including plaque ps…

This study tested the safety and how the body processes an experimental drug called MCI-186 in people who had just experienced a stroke. It involved 36 participants who received the drug or a placebo within 24 hours of their stroke symptoms starting. The main goal was to see if t…

This study tested whether higher doses of a medication called ursodeoxycholic acid (UDCA) were better than a low dose at improving liver health in people with chronic hepatitis C. Nearly 600 patients in Japan took part in this 24-week trial, where neither they nor their doctors k…

This was a very early study to check the safety and basic behavior of a new drug called MP-424 in people with a specific type of chronic Hepatitis C. It involved just 10 patients who had never taken certain other Hepatitis C medications. Researchers gave a single dose and then ca…

This study tested whether a new medication called Teneligliptin (MP-513) could safely help control blood sugar in people with type 2 diabetes. It involved 203 Japanese adults who were managing their diabetes with diet and exercise alone. For 12 weeks, participants received either…

This early-stage study tested a new drug called MT-8554 for women experiencing frequent hot flashes. Researchers wanted to see if the drug was safe and how it affected hot flash frequency and body temperature. The study included 24 women who had at least 7 hot flashes per day, in…

This study tested whether an experimental drug called MT-8554 could safely reduce pain in people with diabetic nerve damage. 61 adults with long-term nerve pain from diabetes received either the drug or a placebo pill to compare effects. Researchers measured changes in pain level…

This study tested whether a drug called MT-5547 could better reduce pain and improve daily movement in people with knee or hip osteoarthritis compared to a placebo (inactive treatment). Over 600 Japanese participants with moderate to severe pain took the drug or a placebo for 16 …

This early-stage study aimed to check the safety and measure how the body processes a new allergy medication called MT-2990. It involved 75 adults with seasonal allergies to Japanese cedar pollen. Researchers gave a single dose and then monitored participants for side effects and…

This study tested if a medication called TAU-284 works as well as an existing drug (ketotifen) to reduce itching in children with atopic dermatitis, also known as eczema. It involved 303 children aged 7 to 15. The main goal was to see if the new treatment was not worse than the s…

This study tested whether a nasal spray called TAU-284 was better than a placebo (a spray with no medicine) at reducing allergy symptoms in children. It involved 473 kids, aged 7 to 15, who suffer from year-round allergic rhinitis (like constant sneezing and a stuffy nose). For t…

This study tested whether an experimental drug called MT-8554 could safely reduce pain in people with painful diabetic nerve damage. 156 participants with moderate nerve pain were randomly assigned to receive either MT-8554 or a placebo pill for 12 weeks. Researchers measured cha…

This study tested whether a nasal spray called TAU-284 was better than a placebo spray at relieving allergy symptoms in children. It involved 490 kids, aged 7 to 15, who suffer from year-round allergic rhinitis (sneezing, runny nose, and congestion). For two weeks, children recei…

This study tested a nasal spray called TAU-284 (bepotastine) in children aged 7 to 15 who have year-round allergic rhinitis. The main goal was to check the long-term safety and effectiveness of using the spray daily for 12 weeks. Researchers measured changes in common allergy sym…

This study aimed to understand how taking iron supplements affects the way a new drug called MT-6548 is processed by the body. It involved 61 healthy male volunteers of Japanese descent. Researchers measured the drug's levels in the blood when taken with and without iron to check…

This study aimed to see if taking a phosphate-lowering drug (colestilan) changes how the body absorbs a common blood pressure medication (candesartan). It involved 18 healthy male volunteers to measure drug levels in the blood under different timing schedules. The goal was to gat…

This study aimed to understand how a drug called MCI-186 is processed by the body in people with mild or moderate liver problems compared to people with normal liver function. It involved 22 participants who received a single dose of the drug. The goal was to gather safety inform…

This early-stage study tested a new oral medication called edaravone in healthy adult men. Researchers wanted to see how the drug interacts with common medications like cholesterol and blood pressure pills, and to check its safety. The study involved 84 healthy volunteers to gath…

This small, completed study aimed to understand how the body absorbs and processes an oral liquid version of the drug edaravone in Japanese patients with ALS (amyotrophic lateral sclerosis) who have a feeding tube (gastrostomy). It involved just 6 participants and focused on meas…

This study aimed to understand how a drug called MCI-186 is processed by the body in people with severe liver disease compared to healthy people. It involved 12 participants who received a single dose, and researchers closely measured drug levels in their blood. The goal was to g…

This small, early-stage study tested how the body absorbs and processes an oral liquid form of edaravone, a drug used for ALS. It involved 9 Japanese patients with ALS to measure drug levels in the blood and check for safety. The goal was to understand how the drug behaves in the…

This study aimed to understand how eating different types of meals affects how the body absorbs and processes an oral form of the drug edaravone. It involved 16 healthy Japanese adults who took the drug under various dietary conditions, including fasting. The main goal was to gat…

This early-stage study aimed to understand how the body absorbs a liquid drug called edaravone when it is swallowed normally compared to when it is delivered through a thin tube placed in the nose and down to the stomach. It involved 36 healthy Japanese adults to check for safety…

This study aimed to understand how a drug called MCI-186 is processed by the body in people with mild or moderate kidney problems compared to people with normal kidney function. It involved 30 participants who received a single dose of the drug. The main goal was to gather inform…

This was an early-stage study to check the safety and see how the body processes a new oral form of a drug called edaravone. It involved 74 healthy adult male volunteers who took single or multiple doses. The main goals were to see if the drug caused any side effects and to measu…

This small, early-stage study looked at how a potential diabetes drug called TA-7284 is processed by the body in people with moderate kidney problems. It compared 24 adults with type 2 diabetes who had either normal or reduced kidney function. The main goal was to understand how …

This early-stage study aimed to see if a new drug candidate, MT-8554, changes how the body processes two common cholesterol-lowering drugs, simvastatin and rosuvastatin. It involved 28 healthy male volunteers to measure drug levels in the blood and check for safety. The goal was …

This was an early, small study to see how a single dose of an experimental compound called MT-8554 affects the body in healthy people. It involved 20 healthy male volunteers and measured how the drug changed their response to a standard cold pain test. The main goals were to unde…

This study aimed to see if a new oral liquid form of the drug edaravone gets into the bloodstream similarly to the existing intravenous (IV) form. It involved 42 healthy Japanese adults who received a single dose of each version. The main goal was to compare the levels of the dru…

This was a first-in-human study to check if a new, undisclosed drug called MT-8554 is safe for people and to see how the body absorbs and processes it. The study involved 135 healthy adult volunteers who received the drug. Researchers closely monitored participants for any side e…

This study aimed to see if an experimental drug called MCI-186 could cause dangerous changes in heart rhythm. It involved 27 healthy male volunteers who received the drug at different doses and a placebo. Researchers carefully monitored their heart activity to check for any safet…