New injection could ease arthritis pain

NCT ID NCT03245008

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a drug called MT-5547 (fasinumab) in 626 Japanese adults with moderate to severe osteoarthritis pain in the knee or hip. Participants received either the drug or a placebo injection for 16 weeks. The goal was to see if the drug reduces pain and improves daily function better than a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MT-5547 (fasinumab) injection

What this could lead to

If successful, this could provide a new treatment option for people with osteoarthritis who have moderate to severe pain.

What could go wrong

This is an early-to-mid-stage trial, so results may not confirm long-term safety or effectiveness. The drug may cause side effects or not work better than a placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, hip osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site

    Aichi, Japan

  • Investigational Site

    Aomori, Japan

  • Investigational Site

    Chiba, Japan

  • Investigational Site

    Ehime, Japan

  • Investigational Site

    Fukui, Japan

  • Investigational Site

    Fukuoka, Japan

  • Investigational Site

    Fukushima, Japan

  • Investigational Site

    Gunma, Japan

  • Investigational Site

    Hiroshima, Japan

  • Investigational Site

    Hokkaido, Japan

  • Investigational Site

    Hyōgo, Japan

  • Investigational Site

    Ibaraki, Japan

  • Investigational Site

    Kagoshima, Japan

  • Investigational Site

    Kanagawa, Japan

  • Investigational Site

    Kumamoto, Japan

  • Investigational Site

    Kyoto, Japan

  • Investigational Site

    Mie, Japan

  • Investigational Site

    Miyagi, Japan

  • Investigational Site

    Miyazaki, Japan

  • Investigational Site

    Osaka, Japan

  • Investigational Site

    Ōita, Japan

  • Investigational Site

    Saitama, Japan

  • Investigational Site

    Shiga, Japan

  • Investigational Site

    Shizuoka, Japan

  • Investigational Site

    Tokyo, Japan

  • Investigational Site

    Yamagata, Japan

  • Investigational Site

    Yamaguchi, Japan