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Can the right anesthesia get knee replacement patients moving faster?

NCT ID NCT07124494

Symptom relief Sponsor: Konya City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial compares three regional anesthesia techniques after total knee replacement to see which one helps patients regain knee movement best. Adults scheduled for knee replacement will be randomly assigned to one of three groups: spinal anesthesia with an epidural, a nerve block, or standard pain medication through an IV. The study measures knee range of motion, pain levels, and patient satisfaction in the first few days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
regional anesthesia techniques (combined spinal-epidural, adductor canal block, multimodal intravenous analgesia)
What this could lead to
If one method proves superior, it could help people recover better after knee replacement with less pain and more movement.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. Any anesthesia method carries risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* Minimum Age: 18 Years * Maximum Age: None * Sex: All * Gender Based: No * Accepts Healthy Volunteers: No * Inclusion Criteria: * Scheduled for primary total knee arthroplasty * Age ≥ 18 years * American Society of Anesthesiologists (ASA) physical status I-III * Accepting neuraxial anesthesia * Exclusion Criteria: * Skin infection at the planned injection site * Sepsis * Coagulopathy * Refusal of neuraxial anesthesia * Severe hypovolemia * Demyelinating central nervous system disease * Age under 18 years * Illiterate in Turkish * Non-cooperative patients * Known allergy or hypersensitivity to bupivacaine

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain, Postoperative Patient Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee range of motion Patient satisfaction Postoperative pain Regional anesthesia Total knee arthroplasty

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Yasin Tire

    RECRUITING

    Konya, Meram, 42140, Turkey (Türkiye)

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