Timing matters: study tests best way to take kidney and blood pressure meds together
NCT ID NCT01976572
First seen Jan 07, 2026 · Last updated Jun 20, 2026 · Updated 34 times
Summary
This completed Phase 1 trial looked at how colestilan, a drug for high phosphate levels in kidney disease, affects the body's processing of candesartan, a blood pressure medication. Eighteen healthy men took candesartan alone or with colestilan at different times. The goal was to see if colestilan changes candesartan levels in the blood, which could help doctors recommend the best dosing schedule for patients who need both drugs.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Covance Clinical Research Unit Ltd.
Leeds, Springfield House Hyde Street, United Kingdom
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
colestilan and candesartan
What this could lead to
If successful, this could help doctors decide the best timing for taking colestilan and candesartan together to avoid drug interactions in people with kidney disease.
What could go wrong
This was a small, early-stage study in healthy volunteers, not patients. Results may not directly apply to people with kidney disease or other health conditions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.