Timing matters: study tests best way to take kidney and blood pressure meds together

NCT ID NCT01976572

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed Phase 1 trial looked at how colestilan, a drug for high phosphate levels in kidney disease, affects the body's processing of candesartan, a blood pressure medication. Eighteen healthy men took candesartan alone or with colestilan at different times. The goal was to see if colestilan changes candesartan levels in the blood, which could help doctors recommend the best dosing schedule for patients who need both drugs.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
colestilan and candesartan
What this could lead to
If successful, this could help doctors decide the best timing for taking colestilan and candesartan together to avoid drug interactions in people with kidney disease.
What could go wrong
This was a small, early-stage study in healthy volunteers, not patients. Results may not directly apply to people with kidney disease or other health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Covance Clinical Research Unit Ltd.

    Leeds, Springfield House Hyde Street, United Kingdom

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