Methodist Health System

This study looked at a procedure called endoscopic sleeve gastroplasty, which reduces stomach size using a flexible tube through the mouth, to help people with obesity lose weight. 75 adults who had trouble losing weight with diet and exercise alone took part. The main goal was t…

This study tested whether a pharmacist-led program could safely reduce the use of acid-suppressing drugs given to prevent stress ulcers in intensive care unit (ICU) patients. 120 adults in the ICU were included, and those without high-risk conditions had their stomach acid medica…

This study tested a new way to help people with obesity lose weight: group doctor visits where each person gets a personal health plan. 11 adults aged 30-60 with a BMI of 35-50 took part. Researchers tracked weight, blood pressure, waist size, and mood to see if this approach wor…

This study tested a procedure called fecal microbiota transplant (FMT) in 24 adults with recurring Clostridium difficile (C. diff) infection. FMT involves placing healthy donor stool into the patient's colon to restore good bacteria killed by antibiotics. The goal was to see if F…

This study tested facial transplantation in 3 people with severe facial deformities from accidents. The goal was to improve their quality of life and facial function. Participants had to take lifelong anti-rejection drugs after the transplant.

This study looked at whether a fixed dose of a clotting drug (4F-PCC) is safe and effective for treating brain bleeds in people taking the blood thinners rivaroxaban or apixaban. Researchers compared the fixed dose to the standard weight-based dose in 76 adults. The goal was to c…

This study looked at a flexible dosing method for delivering tiny radioactive beads (Y90 SIR-Spheres) directly to liver tumors that cannot be surgically removed. The goal was to see how well this approach controls the cancer and affects survival. Only one person took part, so res…

This study looked at whether giving one dose of belatacept to kidney transplant patients whose new kidneys are slow to start working (delayed graft function) can help them recover kidney function faster. The study included 67 adults who received a kidney transplant and had delaye…

This study looked at 45 adults on dialysis who had a blocked major vein in the chest (superior vena cava syndrome). Doctors used surgery or a tube (stent) to reopen or bypass the blockage. The goal was to see how well the repair worked and how long it stayed open.

This study looked at whether giving liver transplant patients fewer immune-suppressing drugs could lower their risk of a serious complication called graft-versus-host disease (GVHD), where donor cells attack the recipient's body. About 100 adults who received a liver or combined …

This study looked at how safe and effective the antibiotic omadacycline is for treating moderate to severe diabetic foot infections, including bone infections, in hospitalized adults. Researchers compared 42 patients who received omadacycline to a similar group who got standard a…

This study tested a special stent system designed to help treat brain aneurysms with a wide neck, which are harder to close with standard methods. The stent acts like a scaffold to keep tiny coils inside the aneurysm, blocking blood flow. Thirty adults with unruptured, wide-neck …

This study looked at how well the drug sacubitril/valsartan works in African American patients with heart failure. Over 6,500 participants were followed for at least three months. The goal was to see if the drug reduces deaths and hospital stays, since earlier research suggested …

This study looked at whether doxycycline, a common antibiotic, can prevent spontaneous bacterial peritonitis (SBP) in people with cirrhosis. SBP is a serious infection of the belly fluid. The study included 841 adults with cirrhosis who were at risk for SBP. Researchers compared …

This study tested whether a nausea relief inhaler can help reduce nausea and vomiting after bariatric (weight-loss) surgery. Fifty adults aged 18 to 65 who had the surgery were included. The goal was to see if the inhaler could lessen the need for extra nausea medications and imp…

This small study tested a procedure called cryoanalgesia, which uses cold to temporarily freeze nerves and relieve pain from broken ribs. The goal was to see if this approach could control pain better than standard treatments and reduce the need for strong painkillers. Five adult…

This study looked at whether mindfulness exercises can lower stress and improve communication between patients with liver disease and their doctors. 56 adults took part. Researchers measured stress, anxiety, and how well patients felt they could share in decisions about their car…

This study looked at whether using smartphone tools can improve work-life balance and reduce burnout for nurse managers who have more than 50 staff members. Six nurse managers from one hospital tried different communication strategies. The goal was to see if these tools could hel…

This study looked at a special imaging tool called NvisionVLE® used during a procedure to examine the bile duct. Researchers reviewed records of 3 adults who had already had the procedure to see if the tool was safe and helpful. The goal was to better understand how well the syst…

This study looked at blood product shortages during the COVID-19 pandemic at a single hospital. Researchers tracked when emergency blood supplies were delayed or unavailable for 100 surgical patients. The goal was to use this information to create better policies for handling blo…

This study looked at whether wearing an activity monitor (like a Fitbit) helps people who had heart surgery get back to their normal activity levels faster. Twelve adults who could walk without help wore the device after surgery. The goal was to see if the tracker motivated them …

This study checked how well hospitals follow guidelines when giving the blood thinner heparin to patients with blood clots or heart issues. Researchers looked at 100 adults to see if their treatment stayed in the safe and effective range. The goal was to find ways to improve pati…

This study tested a simple frailty score (TSFI) in 500 older adults (65+) with physical trauma to see if it could predict complications and death better than age alone. Researchers collected data from multiple hospitals to confirm the score's accuracy. The goal is to help doctors…

This study looked at 26,000 adults who had outpatient vascular procedures (like treating blocked arteries or varicose veins) in a doctor's office instead of a hospital. The goal was to see how often people went home versus needing hospital care, and to track any complications wit…

This study tested a training program that uses artificial intelligence to help charge nurses improve how they communicate during conflicts. 35 nurses from one hospital took part. The goal was to see if the program could boost their confidence in managing difficult situations.

This study looked at how often healthcare workers experience violence at work, including physical and verbal attacks. Researchers surveyed 3,000 employees to measure the types of violence and how it affects their well-being and patient care. The goal was to better understand a pr…

This study looked at how emergency medicine pharmacists used a special agreement to fix outpatient prescription problems after patients left the hospital. Researchers reviewed 350 cases where pharmacists wrote new prescriptions to resolve issues. The goal was to describe what typ…

This study reviewed medical records of 417 adults hospitalized with COVID-19 at four hospitals. Researchers wanted to find out how many patients also had other infections (co-infections) or got new infections later. They also looked at whether these extra infections affected deat…

This study looked at what happens when a full-time chaplain works in a primary care clinic. Researchers wanted to see how often patients or doctors asked for the chaplain and what topics patients discussed. 312 adult patients took part. The goal was to learn how spiritual and emo…

This study looked at how being obese affects hospital stays and recovery in trauma patients aged 60 and older. Researchers compared obese and non-obese patients to see if obesity leads to longer hospital stays, more complications, or higher costs. The goal was to clarify conflict…

This study created a large database of information from nearly 1,000 adult trauma patients with severe arm or leg injuries. Researchers collected details like injury type, treatments received, and outcomes to find ways to improve survival and limb-saving care. The goal was to sup…

This study looked back at medical records of 50 obese adults with HSV encephalitis (a rare brain infection caused by the herpes virus) to see how different ways of calculating acyclovir doses affected their outcomes. Researchers compared dosing based on ideal body weight versus a…

This study reviewed patient satisfaction surveys from 1,800 adults who visited a neurosurgeon at Methodist Health System hospitals or clinics between 2016 and 2020. Researchers looked at scores on communication, care quality, and likelihood to recommend the doctor or hospital. Th…

This study looked at whether patients on newer blood thinners (DOACs) have more bleeding during emergency surgery compared to those on older drugs like warfarin. Only 4 people participated, making it too small to draw strong conclusions. The goal was to help doctors better unders…

This study created a large database of abdominal aortic aneurysm (AAA) surgeries across 138 hospitals in North Texas. Researchers collected information from 394 patients aged 50 and older who had open or endovascular repair. The goal was to track survival, re-operation, and ruptu…

This study gathered information from 69 older adults (age 40 and up) who had a traumatic brain injury (TBI) confirmed by CT scan. Researchers looked at patients' health history, frailty, and treatments to find patterns that lead to better recovery. No new treatments were tested—t…

This study looked at 197 ICU patients with gram-negative bacterial infections to see if using the same antibiotic as before leads to more drug resistance. Researchers compared patients who got the same IV antibiotics again versus those who got a different type. The goal was to un…

This study examined 263 patients with NASH (a type of fatty liver disease) to see how factors like age, other health problems, and medications relate to the severity of liver scarring. Researchers reviewed medical records from 2013 to 2020. The goal was to better understand which…

This study looked at 100 fully vaccinated adults who later tested positive for COVID-19. Researchers compared infection rates between people who only had the initial vaccine series and those who also got a booster shot. The goal was to understand how often breakthrough infections…

This study checked if testing patients for certain drug-resistant bacteria (called MDR gram-negative organisms) when they enter the hospital can predict if they will later get an infection from those same germs. Researchers looked back at records of nearly 2,900 adult patients wh…

This study looked back at the medical records of 504 adults with small bowel obstruction to see how using a special contrast drink affected their hospital stay and recovery. The goal was to find ways to improve safety, shorten hospital stays, and reduce complications. The study d…

This study reviewed the medical records of 8 men treated for breast cancer at Methodist Health System. The goal was to understand their backgrounds, how the cancer responded to treatment, and long-term outcomes like survival and recurrence. Because it only looked back at past dat…

This study examined how a new U.S. policy for distributing donated livers changed costs for one transplant center. Researchers compared costs and transplant volumes before and after the policy took effect in February 2020. They looked at 186 adults who received a liver transplant…

This study looked at what happens to pregnant women and their babies when they need emergency surgery for problems like appendicitis or gallbladder disease. Researchers collected information from 3 pregnant women to learn more about how surgery affects pregnancy. The goal was to …

This study looked at hospital records of 132 ICU patients with pneumonia to find out why some infections are resistant to common antibiotics. The goal was to identify risk factors for drug-resistant bacteria. The results may help doctors choose better treatments for these serious…

This study tested a risk prediction tool (ADE-RED) to identify emergency department patients at high risk for adverse drug events that could lead to a return visit or hospitalization. Researchers enrolled 471 patients and tracked whether the tool helped reduce these events. The g…

This study looked at 945 adults with septic shock in the ICU to compare two ways of giving blood pressure medicines (vasopressors): one based on the patient's weight and one not. The goal was to see if one approach leads to better outcomes or fewer side effects. Researchers also …