Shorter antibiotic course may be just as good for facial fractures
NCT ID NCT04925531
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looked at whether giving antibiotics for 3 days instead of 5 days after facial fracture surgery makes a difference in preventing infections. Researchers enrolled 143 trauma patients to compare the two durations. The goal is to find the shortest effective antibiotic course to reduce side effects and antibiotic resistance.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Antibiotics (ampicillin, cefazolin, erythromycin)
- What this could lead to
- If shorter antibiotic use works as well, it could reduce side effects and bacterial resistance in facial fracture patients.
- What could go wrong
- This is a small, completed study with 143 patients, so results may not apply to everyone. The best antibiotic duration is still uncertain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Methodist Dallas Medical Center
Dallas, Texas, 75203, United States
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