Can a Lab-Grown artery save injured limbs?

NCT ID NCT07762794

Not yet recruiting Disease control Sponsor: Humacyte, Inc. Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study is testing a lab-grown blood vessel called Symvess in adults who have suffered a serious injury to an artery in their arm or leg. The goal is to see how well the vessel stays open and functions over a year, and whether it helps avoid amputation and infection. Participants will receive Symvess during surgery and will be followed for up to 12 months with imaging and check-ups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Symvess (Acellular Tissue Engineered Vessel), a lab-grown blood vessel used to replace or repair damaged arteries
What this could lead to: If successful, this could confirm that Symvess is a reliable, infection-resistant option for repairing severe limb artery injuries, potentially reducing amputations and improving recovery.
What could go wrong: This is an observational study without a comparison group, so results may be influenced by other factors. Risks include possible vessel blockage, infection, or need for additional surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Accidental Injuries injury Vascular System Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTERIAL INJURY TRAUMA INJURY VASCULAR INJURY

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