Lab-Grown vessel could save Teens' limbs after severe injury
NCT ID NCT07762313
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether a lab-grown blood vessel called SYMVESS can safely repair damaged arteries in the arms or legs of adolescents when their own veins aren't suitable. The study enrolls teens up to age 17 with severe arterial injuries that threaten limb loss. Participants receive the vessel implant and are monitored for a year to check how well it stays open, prevents infection, and avoids amputation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Acellular Tissue Engineered Vessel (Symvess), a lab-grown blood vessel made from human cells that is implanted to replace a damaged artery.
- What this could lead to
- If successful, this could provide a safe, ready-made option for repairing severe limb artery injuries in adolescents, potentially reducing amputations and improving recovery.
- What could go wrong
- This is a small early-stage trial, and the vessel may fail to stay open, become infected, or cause side effects. Long-term safety and effectiveness are not yet established.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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