New antibiotic could be safer for diabetic foot infections

NCT ID NCT04714411

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested the antibiotic omadacycline in 42 hospitalized adults with diabetic foot infections, some with bone infection. The goal was to see if it causes fewer kidney problems and gut infections compared to standard antibiotics. Researchers compared results to a group of similar patients who received usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Omadacycline (an antibiotic)

What this could lead to

If successful, this could show that omadacycline is a safer antibiotic option for diabetic foot infections, reducing the risk of kidney damage and gut infections.

What could go wrong

This is a small, early study with only 42 participants. Results may not apply to all patients, and the drug may still cause side effects or not work as well as expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteomyelitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Methodist Charlton Medical Center

    Dallas, Texas, 75237, United States

  • Methodist Dallas Medical Center

    Dallas, Texas, 75203, United States