New antibiotic could fight tough diabetic foot infections

NCT ID NCT05369052

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Phase 3 trial tests a new antibiotic called contezolid against a standard one (linezolid) for moderate to severe diabetic foot infections. About 865 adults with diabetes and a foot infection will receive either drug for 2 to 4 weeks. The goal is to see if the new drug works as well or better and has fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
contezolid acefosamil (IV) and contezolid (oral)
What this could lead to
If successful, this could provide a new antibiotic option for treating serious diabetic foot infections, potentially with fewer side effects than current treatments.
What could go wrong
This is an early Phase 3 trial, so results are not yet proven. The new drug may not be more effective or safer than the existing antibiotic linezolid.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Daugavpils Regional Hospital

    RECRUITING

    Daugavpils, Latvia

  • GMV Care& Research - Maria Cecilia Hospital

    RECRUITING

    Cotignola, Italy

  • ILD Research Center

    RECRUITING

    Vista, California, 92081, United States

  • Instytut Medycyny Wsi im. W. Chodzki

    RECRUITING

    Lublin, Poland

  • JSC Vian - West Georgia Medical Center

    RECRUITING

    Kutaisi, Georgia

  • LTD High Technology Hospital Med Center

    RECRUITING

    Batumi, Georgia

  • MHAT Sveti Nikolay Chudotvorets EOOD

    RECRUITING

    Lom, Bulgaria

  • Medical Institute Ministry of Interior Central Clinical Base

    RECRUITING

    Sofia, Bulgaria

  • Multiprofile Hospital for Active Treatment - KANEV

    RECRUITING

    Rousse, Bulgaria

  • New Hope Research Development

    RECRUITING

    Corona, California, 92882, United States

  • PODEMA Sp. z o.o.

    RECRUITING

    Warsaw, Poland

  • South-Estonian Hospital Ltd.

    RECRUITING

    Võru, Estonia

  • University Clinical Center Kragujevac

    RECRUITING

    Kragujevac, Serbia

  • University Multidisciplinary Hospital for Active Treatment and Emergency Medicine 'N. I. Priogov´

    RECRUITING

    Sofia, Bulgaria

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