Bone injection may beat IV for preventing amputation infections in diabetics

NCT ID NCT07338773

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 5 times

Summary

This study tests whether giving the antibiotic vancomycin directly into the bone (intraosseous) during diabetic foot amputation works better than the standard IV method to prevent surgical site infections. It includes 40 adults with diabetes who need a below-knee amputation. Researchers will measure antibiotic levels at the wound and track infections, kidney function, and need for repeat surgeries over 90 days.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Basaksehir Cam ve Sakura City Hospital

    Istanbul, Istanbul, 34010, Turkey (Türkiye)

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