Methodist Health System
Clinical trials sponsored by Methodist Health System, explained in plain language.
-
Stomach balloon shows promise for fatty liver – but more proof needed
Disease control ENROLLING_BY_INVITATIONThis study follows 200 people with nonalcoholic fatty liver disease (NAFLD) who receive an intragastric balloon—a device placed in the stomach to help with weight loss. Researchers will track changes in weight, liver enzymes, blood sugar, and liver stiffness for at least one year…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
-
PCOS drug study pulled before it began
Disease control TerminatedThis study aimed to test semaglutide in women with polycystic ovary syndrome (PCOS) to see if it helps with weight and treatment adherence. It was designed for women aged 18-45 with a BMI over 30. However, the study was withdrawn before enrolling any participants, so no results a…
Phase: PHASE1 • Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
-
Simple class aims to keep seniors from falling again
Prevention ENROLLING_BY_INVITATIONThis study looks at whether a fall prevention discharge class can reduce repeat fall-related ER visits in adults aged 60 and older. Researchers will compare those who attended the class to those who did not. The goal is to see if this simple education step can help prevent future…
Sponsor: Methodist Health System • Aim: Prevention
Last updated Jun 27, 2026 11:03 UTC
-
Constipation study for back surgery patients withdrawn before starting
Symptom relief TerminatedThis study was designed to see if the drug RELISTOR could help relieve constipation caused by opioid painkillers in people who had spinal fusion surgery. It planned to compare RELISTOR to standard laxatives in 40 patients. However, the study was withdrawn before enrolling anyone,…
Sponsor: Methodist Health System • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
-
New registry aims to unlock secrets of aortic injury from car crashes
Knowledge-focused OngoingThis study is building a database of information about blunt thoracic aortic injury (BTAI), a serious condition often caused by car accidents or falls. Researchers will look at how patients are diagnosed, treated, and how they recover over time. The goal is to learn from real-wor…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
-
Massive new registry aims to unlock secrets of vascular trauma
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects detailed information from thousands of trauma patients who have suffered injuries to their blood vessels (vascular injuries). The goal is to build a large database that doctors can use to understand how these injuries happen, how they are treated, and what the…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
-
Researchers look back at liver treatments to find what works best
Knowledge-focused OngoingThis study reviews medical records of 126 adults treated for liver or bile duct diseases (both non-cancerous and cancerous) since 2005. The goal is to see how well different treatments work and to find ways to improve survival, control symptoms, and lower risks. No new treatments…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
-
Pandemic's hidden toll: frailty rises in liver transplant hopefuls
Knowledge-focused OngoingThis study examines whether the COVID-19 pandemic increased frailty and muscle loss (sarcopenia) in people waiting for a liver transplant. Researchers will compare data from 208 patients assessed before and during the pandemic. The goal is to understand how the pandemic affected …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
-
COVID-19 heart risks under review
Knowledge-focused TerminatedThis study looks at heart problems in adults hospitalized with COVID-19. Researchers will review medical records to see how often heart issues like heart failure, inflammation, or arrhythmias occur. No new treatments are tested; the goal is to learn more about the virus's effects…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
-
Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
-
Hormone clues in cirrhosis and low blood pressure study withdrawn
Knowledge-focused TerminatedThis study was designed to measure estrogen and testosterone levels in men with liver cirrhosis who also have low blood pressure, compared to those with cirrhosis but normal blood pressure. The goal was to understand why low blood pressure occurs in cirrhosis. However, the study …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Nurse safety survey pulled before it began
Knowledge-focused TerminatedThis study was designed to survey nurses and staff at Methodist Richardson Medical Center about their experiences with workplace violence from patients and visitors. The goal was to understand how prepared staff feel and how often they face abuse. However, the study was withdrawn…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Study on best drugs for emergency breathing tubes in trauma patients withdrawn
Knowledge-focused TerminatedThis study aimed to find out which drug combinations are most commonly used when trauma patients need a breathing tube in the emergency department. Researchers planned to review medical records from several Texas trauma centers to see how different drug regimens affect patient ou…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Liver tumor treatment study halted before it began
Knowledge-focused TerminatedThis study aimed to review past cases of a treatment called radioembolization (using tiny radiation beads) for liver tumors, including a rare type of bile duct cancer. The goal was to understand how well it works and what risks it carries. However, the study was withdrawn before …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Nurse incivility study pulled before it began
Knowledge-focused TerminatedThis study was designed to understand how rude behavior among coworkers affects nurses' sense of meaning, joy, and confidence at work. It planned to survey nurses and nursing assistants across four hospitals. However, the study was withdrawn before enrolling any participants, so …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Antibiotic study for broken legs canceled before it began
Knowledge-focused TerminatedThis study aimed to find out if adding a strong antibiotic (aminoglycoside) to a standard one (cephalosporin) helps people with open leg fractures. It was planned for adults with severe open fractures, but the study was withdrawn and no one took part. No results are available.
Phase: PHASE3 • Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
-
Hidden virus threat in dual organ transplants revealed
Knowledge-focused ENROLLING_BY_INVITATIONThis study reviews medical records of 50 adults who received a simultaneous liver-kidney transplant between 2015 and 2020. Researchers want to find out how many of them developed BK virus in their blood, which can harm the new kidney. The goal is to better understand this risk in…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
-
New protocol aims to speed up pancreatitis recovery
Knowledge-focused OngoingThis study looks at whether a standard set of guidelines, called the Methodist Acute Pancreatitis Protocol (MAPP), improves care for people with acute pancreatitis. Researchers will compare outcomes like hospital stay length and discharge status before and after the protocol was …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
-
Heart test bias? study probes racial gaps in heart failure diagnosis
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether standard blood tests for heart failure show different results in African American and Caucasian patients. Researchers will compare levels of cardiac biomarkers in 400 adults newly diagnosed with heart failure. The goal is to see if current tests miss o…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
-
Are repeat back surgeries riskier? new study investigates
Knowledge-focused OngoingThis study looks at medical records of 3,500 adults who had a type of back surgery called ALIF between 2010 and 2020. The goal is to see if death rates from this surgery have gone down over the years and whether having a second surgery is riskier than the first. Researchers hope …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC