Istinye University

This study tests a new exercise approach for people with COPD, a lung disease that makes breathing hard. Researchers will compare standard pulmonary rehab with a version that uses a blood flow restriction cuff during low-intensity aerobic exercise. The goal is to see if this meth…

This study tests whether adding core stability exercises and inspiratory muscle training (using a breathing device) to regular soccer practice improves muscle oxygenation and athletic performance in 54 male soccer players aged 15-18. Over 8 weeks, players will be split into three…

This study looks at whether a gentle stretching technique called neural mobilization can immediately improve balance and body awareness in people with low back pain that also travels down the leg. Researchers will compare the nerve stretch to a fake (sham) version in 52 adults. T…

This study tests whether a single session of a mental practice technique called PETTLEP-based Action Observation and Motor Imagery (AOMI) can immediately improve arm movement in stroke survivors. Participants will either watch and mentally rehearse a reach-to-grasp task or do a c…

This study tests a 4-week rhythm-based exercise program for video gamers who have scapular dyskinesis, a condition where the shoulder blade moves abnormally. 42 gamers aged 18-35 will do specific stabilization exercises on stable and unstable surfaces. The goal is to see if these…

This study looks at whether adding pain neuroscience education to a walking program can reduce abdominal pain, symptom severity, and stress levels in people with irritable bowel syndrome (IBS). Thirty-three adults with IBS will be split into three groups: exercise alone, exercise…

This study looks at three ways to manage pain after mastectomy: standard pain medication, a nerve block called rhomboid intercostal block (RIB), or a combination of RIB with another nerve block. Researchers will review medical records of 66 women to see which method provides the …

This study looks at whether 8 weeks of inspiratory muscle training can improve thinking, brain oxygen levels, and brain healing in 42 adults with moderate obstructive sleep apnea. Participants will do breathing exercises daily and be compared to those receiving a low-intensity ve…

This study tests whether playing video games that involve breathing exercises can improve lung function and exercise capacity in people with interstitial lung disease. 42 participants will be split into two groups: one doing standard rehab, the other adding video game-based exerc…

This study looks at different ways to manage pain after a type of kidney stone surgery called PCNL. Researchers will track how much opioid pain medicine patients need and their pain levels. The goal is to find which method works best to reduce pain and limit opioid use.

This study tests a simple, drug-free way to reduce pain when getting an IV in people with obesity (BMI over 30). Researchers will apply a cold marble stone to the side of the neck for 5 seconds before inserting the IV. They believe this may stimulate the vagus nerve and lower pai…

This study will measure balance, coordination, and reaction time in 41 adults aged 18-40 who experience motion sickness. Participants will complete a series of physical tests and a controlled motion sickness provocation session. The goal is to see how these sensorimotor skills re…

This study looks at how stroke survivors with weakness on one side (hemiplegia) perceive internal body signals, like heartbeat, and whether that relates to their balance, touch sensation, and joint position sense. Researchers will assess 60 participants in a single session using …

This study looks at whether professional soccer players with stronger lungs and breathing muscles also have better balance, faster reaction times, and greater endurance. Researchers will measure lung function, breathing strength, balance, core stability, and reaction speed in 31 …

This study will check if measuring belly muscle thickness with ultrasound before surgery can help predict how much opioid pain medicine older patients need after abdominal surgery. Researchers will follow 62 patients aged 65 and older for 24 hours after surgery, recording pain sc…

This study follows 100 adults having their thyroid removed to see how different pain relief methods (like a nerve block) affect recovery and swallowing pain. It is purely observational, meaning no new treatment is given. The goal is to gather information to improve future care.

This study will check if low bicarbonate levels in the blood can predict when adult ICU patients will have trouble with tube feeding. Researchers will watch 70 patients for 72 hours after they start feeding. The goal is to find a simple way to identify patients at risk, so doctor…

This study looks at whether Kinesio Taping can immediately improve hand and arm function in healthy adults. Thirty-six participants will be randomly assigned to receive real Kinesio Tape, sham tape (no tension), or no tape at all. They will perform tests like grip strength, typin…

This study observes 90 adults undergoing nose surgery to see if a standard dose of tranexamic acid (a drug to reduce bleeding) affects how often anesthesiologists need to adjust pain medication. The goal is to understand if patient weight plays a role in anesthesiologist workload…

This study looks at whether professional e-sports players are more physically fit than amateur players. Researchers will measure reaction time, endurance, and grip strength in 40 adults aged 18 to 30. The goal is to understand how different levels of gaming affect physical health…

This study watches 100 adults after a sedated upper GI endoscopy to see how often their oxygen levels drop below normal. Researchers will track these episodes and any breathing problems that follow, without changing standard care. The goal is to better understand and improve reco…

This study watches how carbon dioxide gas, used to inflate the belly during laparoscopic weight-loss surgery, changes blood bicarbonate levels. Researchers will track 85 adults having sleeve gastrectomy or gastric bypass to see if these changes relate to how long the gas is used …

This study watches how the breathing machine's settings during laparoscopic belly surgery may affect lung problems after surgery. Researchers will record machine data during surgery for 90 adults and check for complications like low oxygen or needing breathing help. No changes ar…

This observational study will track 100 adults having laparoscopic gallbladder surgery to see how body mass index, sleep apnea risk, and pain relief methods relate to oxygen levels right after surgery. No extra treatments are given—just routine care. The goal is to better underst…

This study checks if a Turkish version of the Respiratory Distress Observation Scale (RDOS) accurately measures breathing distress in critically ill patients who cannot speak. Researchers will compare RDOS scores with end-tidal carbon dioxide levels, an objective breathing measur…

This study looks at whether a routine blood test taken before septorhinoplasty (nose surgery) can help predict how much pain a person will feel right after the operation. Researchers will check the ratio of two types of white blood cells (neutrophils and lymphocytes) and other bl…

This observational study looks at whether a quick, non-invasive breathing score (the ROX index) can predict low oxygen levels right after nose or sinus surgery. Researchers will follow 80 adults having elective septorhinoplasty or endoscopic sinus surgery. The goal is to see if t…

This study watches how the diaphragm moves before and after gallbladder removal surgery. It checks if changes in movement are linked to lower oxygen levels after the operation. About 62 adults having planned surgery will take part. No new treatment is tested—only measurements are…

This study will follow 110 adults with sepsis in the ICU to see if the amount of oxygen they receive in the first 24 hours is linked to changes in a blood marker called the uric acid/albumin ratio (UAR). The UAR may indicate oxidative stress and inflammation. Researchers will not…

This study looks at whether combining two blood markers—uric acid/albumin ratio and lactate—can help predict which older adults (65+) with sepsis will develop kidney injury, need blood pressure support, or die within 28 days. Researchers will follow 80 ICU patients who do not hav…

This study will check if a simple breathing measurement called the ROX index, taken before bariatric surgery, can predict which patients will have low oxygen levels in the first 12 hours after surgery. Researchers will measure the ROX index along with other risk scores in 80 adul…

This study aims to find out how much surgeons know about getting patients ready for surgery. Researchers will test 60 surgeons before and after a training session to see if their knowledge improves. The goal is to identify gaps and improve hospital training, not to test a new tre…

This study looks at how people with chronic low back pain perceive their body signals, their activity levels, and their emotional state. Researchers will survey 130 adults aged 18-65 to see how these factors relate to pain intensity. The goal is to better understand the whole pic…

This study looks at how lying in a head-up position (Reverse Trendelenburg) after laparoscopic gallbladder surgery affects oxygen levels in the blood. Researchers will compare obese and non-obese patients and also use the STOP-BANG score to check for sleep apnea risk. The goal is…

This study tests whether a 6-week program of gaze stabilization, core and shoulder exercises, balance training, and cognitive drills can improve shooting accuracy and muscle control in young archers. Twenty-two licensed archers aged 15–18 will be split into an exercise group and …