Could too much oxygen harm sepsis patients? new study investigates

NCT ID NCT07332637

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 110 adults with sepsis in the ICU to see if the amount of oxygen they receive in the first 24 hours is linked to changes in a blood marker called the uric acid/albumin ratio (UAR). The UAR may indicate oxidative stress and inflammation. Researchers will not change any treatments—they will simply observe standard care and measure UAR at admission and 24 hours later. The goal is to learn whether high oxygen exposure might cause extra stress on the body and whether UAR could be a useful early warning sign.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could show that a simple blood test (uric acid/albumin ratio) can help doctors monitor oxygen-related stress in sepsis patients, potentially guiding safer oxygen use.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly change care. It only looks at a small group of 110 patients, and results may not apply to all sepsis patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperoxia infectious disease with sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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