Istanbul University
Clinical trials sponsored by Istanbul University, explained in plain language.
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New knee arthritis combo therapy tested for better healing
Disease control CompletedThis study tested if combining two procedures works better than one for knee arthritis. 50 patients with moderate knee arthritis received either a cell therapy injection alone or that injection plus a bone marrow stimulation technique. Researchers measured pain, function, and car…
Phase: NA • Sponsor: Istanbul University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Which tooth test works best? study puts cold, heat, and electric pulp tests to the test
Diagnosis CompletedThis study aimed to find out how accurate common dental tests are at telling if a tooth's nerve is alive or dead. Researchers tested 175 adults who needed a root canal, using cold, heat, and a small electric current on their tooth. They then compared the test results to what they…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Mar 23, 2026 15:19 UTC
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Could a simple scan replace uncomfortable nerve tests for wrist pain?
Diagnosis CompletedThis study aimed to see if ultrasound scans could be a good alternative to standard nerve tests for diagnosing carpal tunnel syndrome (CTS). Researchers compared ultrasound measurements of the median nerve in 75 people, including healthy individuals and those with mild to moderat…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Mar 20, 2026 14:47 UTC
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Can simple neck exercises beat jaw splints for pain relief?
Symptom relief CompletedThis study tested whether adding specific neck and posture exercises to standard jaw splint therapy works better for reducing pain and improving movement in people with jaw joint disorders. Fifty-seven adults with jaw pain were split into three groups: one used only a jaw splint,…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Gallbladder surgery pain relief: which nerve block works best?
Symptom relief CompletedThis study compared two different nerve-block techniques to manage pain after laparoscopic gallbladder removal surgery. Researchers tested whether an erector spinae plane block or a thoracic paravertebral block was more effective at reducing patients' need for opioid pain medicat…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Can video calls help kids with cerebral palsy move better?
Symptom relief CompletedThis study tested whether a special arm therapy delivered through video calls (telerehabilitation) could help children with one-sided cerebral palsy use their affected arm better. Forty-two children were split into two groups: one received the guided online therapy, and the other…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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Sweet relief? sugar injections tested for stubborn shoulder pain
Symptom relief CompletedThis study tested whether injections of a sugar-water solution (dextrose prolotherapy) could reduce pain and improve movement in people with long-term rotator cuff shoulder problems. 60 patients who still had pain after standard treatments were randomly assigned to receive either…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Mar 16, 2026 15:23 UTC
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High-Tech mouthguard aims to stop jaw pain
Symptom relief CompletedThis study tested if a custom-made mouth splint, designed using a device that tracks a person's unique jaw movements, works better than a standard splint for people who grind their teeth. Forty adults with mild-to-moderate teeth grinding or jaw pain were randomly given either the…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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Can restricting blood flow during Push-Ups boost your arm explosiveness?
Knowledge-focused CompletedThis study looked at how doing push-ups with a special cuff that partially restricts blood flow affects short-term explosive arm power. Researchers tested 30 young volleyball players, having them perform push-ups under three different conditions: with blood flow restriction, with…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Apr 02, 2026 02:11 UTC
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Dental x-rays could reveal hidden signs of gum disease
Knowledge-focused CompletedThis study looked at whether standard dental X-rays can show differences in jawbone quality between people with gum disease and healthy people. Researchers analyzed 120 existing X-rays using special computer measurements to compare bone patterns. The goal was to see if these X-ra…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists investigate hidden hormone link in rare neurological disease
Knowledge-focused CompletedThis small, completed study aimed to understand if people with Friedreich's ataxia have problems producing certain hormones. Researchers compared detailed hormone measurements from 11 patients with the disease to 15 healthy volunteers. The goal was to gather new knowledge about t…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists hunt for immune clues in mysterious kidney disease
Knowledge-focused CompletedThis study aimed to better understand a serious autoimmune kidney disease called primary membranous nephropathy. Researchers analyzed specific immune cells (T-cells and B-cells) in the blood of 44 patients over two years to see how these cells relate to treatment success, relapse…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Dentists seek gentler way for perfect tooth scans
Knowledge-focused CompletedThis study tested different methods dentists use to gently push back the gum line before taking a digital scan of a tooth. Researchers compared four techniques on 32 healthy participants to see which one provided the clearest scan picture while causing the least bleeding and disc…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:27 UTC
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Scientists map hormone shifts in teens with PCOS on birth control
Knowledge-focused CompletedThis study aimed to understand how birth control pills affect hormone levels in teenagers and young women with Polycystic Ovary Syndrome (PCOS). Researchers measured detailed hormone profiles in 56 participants aged 13-21. They compared levels before and after 6 months of birth c…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Survey reveals gaps in ICU eye care knowledge
Knowledge-focused CompletedThis study surveyed 190 nurses working in intensive care units (ICUs) around the world. The goal was to understand their current knowledge, attitudes, and daily practices regarding eye care for critically ill patients. The results will help identify where education and training a…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Simple blood test could forecast who benefits most from obesity surgery
Knowledge-focused CompletedThis study aimed to see if a blood test taken before weight loss surgery could predict how well a patient would do afterward. Researchers followed 23 patients who had gastric bypass surgery, checking their blood for a marker called PTX3 beforehand. They then tracked the patients'…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Scientists probe hidden toll of Obesity-Related breathing disorder
Knowledge-focused CompletedThis study aimed to understand if a breathing disorder linked to obesity makes things worse for people's fitness and daily life. Researchers compared 64 people with obesity, some with and some without the specific breathing condition. They measured how far people could walk, thei…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC
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Dose response association between cerclage construct count and deep infection after femoral and periprosthetic femoral fracture fixation: a Dual-Center retrospective cohort study
CompletedThe purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections. Cerclage wiring is a common technique used to hold bone fragments toge…
Sponsor: Istanbul University
Last updated Mar 02, 2026 15:26 UTC