Istanbul University
Clinical trials sponsored by Istanbul University, explained in plain language.
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Fat cell therapy plus microfracture shows promise for knee arthritis relief
Disease control CompletedThis study tested whether combining a patient's own fat-derived cells (stromal vascular fraction) with a minor surgical procedure called microfracture can improve knee osteoarthritis better than the cell therapy alone. Fifty adults with moderate knee arthritis were randomly assig…
Phase: NA • Sponsor: Istanbul University • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Gum treatment may lower body inflammation and improve cholesterol
Disease control CompletedThis study looked at whether non-surgical gum disease treatment could reduce body-wide inflammation and improve blood fat levels in young adults with severe periodontitis. Fifty participants, including a healthy comparison group, were followed for 6 months after deep cleaning and…
Phase: NA • Sponsor: Istanbul University • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Tooth nerve tests put to the test: which one tells the truth?
Diagnosis CompletedThis study looked at how well cold, heat, and electric tests can tell if a tooth's nerve is alive or dead. 175 adults with teeth needing root canal treatment took part. The test results were compared to what doctors saw when they opened the tooth. The goal was to find out which t…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated May 17, 2026 08:14 UTC
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Simple home program cuts fall risk for seniors
Prevention CompletedThis study tested a nurse-led home program to help older adults at high risk of falling. 82 seniors aged 65+ took part. The program focused on exercise, safety checks, and education to reduce falls and improve balance and quality of life.
Phase: NA • Sponsor: Istanbul University • Aim: Prevention
Last updated May 17, 2026 08:02 UTC
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New study finds best nerve block to slash opioid use after gallbladder surgery
Symptom relief CompletedThis study tested two different numbing injections (erector spinae plane block and thoracic paravertebral block) in 120 adults having gallbladder removal surgery. The goal was to see which one better reduces the need for opioid painkillers in the first 24 hours after surgery. Res…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 17, 2026 08:12 UTC
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High-Tech mouthguards could stop jaw pain and teeth grinding
Symptom relief CompletedThis study tested whether custom mouthguards designed using a jaw-tracking device called MODJAW work better than standard mouthguards for people with teeth grinding (bruxism) or jaw joint pain. Forty adults with mild-to-moderate symptoms used either a custom or standard splint fo…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 17, 2026 08:01 UTC
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Less airflow, better lungs? new study tests anesthesia tweak in obesity surgery
Symptom relief CompletedThis study tested whether using a lower amount of fresh gas during anesthesia (low-flow) could reduce lung collapse (atelectasis) after laparoscopic weight-loss surgery. Sixty adults were randomly assigned to receive either low-flow or normal-flow anesthesia. The researchers meas…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 17, 2026 08:00 UTC
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Simple exercises may boost mouthguard therapy for jaw disorder sufferers
Symptom relief CompletedThis study looked at whether adding specific postural exercises to standard mouthguard therapy can better reduce pain and improve jaw movement in people with internal temporomandibular joint (TMJ) disorders. Fifty-seven adults were split into three groups: one received only a mou…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Virtual therapy shows promise for kids with cerebral palsy
Symptom relief CompletedThis study compared a special hand therapy (mCIMT) delivered via video calls to a standard home program in 42 children with unilateral cerebral palsy. The telerehabilitation group did therapy for 1 hour, 3 times a week for 6 weeks, plus daily activities. The goal was to see if re…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Sugar water shots ease shoulder pain in new study
Symptom relief CompletedThis study tested whether injecting a sugar solution (dextrose prolotherapy) into the shoulder could reduce pain and improve function in people with chronic rotator cuff disease. Sixty adults aged 30 to 65 with shoulder pain lasting more than 3 months took part. The treatment aim…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Picture this: no more fear of the dentist!
Symptom relief CompletedThis study tested whether showing children pictures and explaining the dental environment before treatment could lower their anxiety. 70 children aged 5 to 14 took part, with half receiving the visual lesson and half getting standard care. The results showed that the visual group…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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More wires, more worry: study links cerclage count to infection after femur surgery
Knowledge-focused CompletedThis study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that using more wires was linked to a higher risk of deep infection and persistent wound drainage. The find…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 17, 2026 08:12 UTC
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Scientists map immune cells in kidney disease to predict relapse
Knowledge-focused CompletedThis study looked at immune cells in the blood of 44 people with membranous nephropathy, a kidney disease. Researchers tracked T- and B-cell levels over two years to see how they relate to treatment response and relapse. The goal was to better understand the disease, not to test …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 17, 2026 08:05 UTC
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Blood marker may forecast success of Weight-Loss surgery
Knowledge-focused CompletedThis study tested whether a blood protein called PTX3 can predict how much weight people lose and how their metabolism improves after gastric bypass surgery. Researchers followed 23 adults with obesity for 6 months after surgery. The goal was to see if PTX3 levels before surgery …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 17, 2026 08:02 UTC
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New study reveals hidden impact of breathing disorder in obesity
Knowledge-focused CompletedThis study looked at 64 obese adults to see if having obesity hypoventilation syndrome (OHS) adds extra problems beyond obesity alone. Researchers measured exercise capacity, muscle strength, and quality of life using walking tests and questionnaires. The goal was to understand h…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 17, 2026 08:00 UTC
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Ultrasound reveals hidden clues in carpal tunnel syndrome
Knowledge-focused CompletedThis study looked at 75 people—some healthy and some with mild or moderate carpal tunnel syndrome—to see if ultrasound measurements of the median nerve can help diagnose the condition. Researchers measured nerve size at the wrist and forearm and compared these to pain, symptom se…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Rare disease hormone puzzle: new study looks for answers
Knowledge-focused CompletedThis study looked at whether people with Friedreich's ataxia have trouble making certain hormones. Researchers measured hormone levels in 11 patients and compared them to 15 healthy volunteers. The goal was to learn more about how the disease affects the body's hormone system, no…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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X-Ray analysis reveals hidden bone changes in gum disease patients
Knowledge-focused CompletedThis study looked at jawbone X-rays from 120 people—half with gum disease (periodontitis) and half healthy—to see if computer analysis could spot bone differences. Researchers used special software to measure bone patterns and thickness. The goal is to find better ways to detect …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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New study checks if pressure injury scale works in turkish ICUs
Knowledge-focused CompletedThis study looked at whether a tool called EVARUCI, which helps predict pressure injuries (bedsores) in intensive care patients, works well in Turkish hospitals. Researchers translated it into Turkish and tested it with 100 adult ICU patients who had no pressure injury when they …
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Emergency disconnect: do dialysis patients know how?
Knowledge-focused CompletedThis study looked at whether people on hemodialysis know how to safely disconnect themselves from the machine during an emergency, like a fire or power outage. Researchers tested 620 patients from multiple countries using a checklist. The goal was to see if training helps patient…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Oxygen during surgery: does more help or harm?
Knowledge-focused CompletedThis study measured how giving higher or normal oxygen levels during laparoscopic lower abdominal surgery affects certain substances in the blood related to lung stress, inflammation, and blood vessel health. 76 adults took part, and researchers compared the two oxygen strategies…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Do ICU nurses know how to protect Patients' eyes?
Knowledge-focused CompletedThis study surveyed 190 intensive care unit nurses from around the world to find out what they know and think about eye care for their patients. The goal was to see if nurses follow the latest guidelines for preventing eye problems in critically ill patients. The results help ide…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Dental study reveals best retraction method for clearer scans
Knowledge-focused CompletedThis study looked at different ways to move gum tissue aside during dental scans to see which method gives the best balance of clear images, patient comfort, and minimal tissue movement. Researchers studied 50 healthy adults with thick gums and good oral health. The goal is to he…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 07, 2026 18:39 UTC
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PCOS pill study reveals hormone shifts in young women
Knowledge-focused CompletedThis study looked at 56 teens and young women with PCOS to see how birth control pills change their hormone levels over 6 months. Researchers used a precise method to measure hormones before and after treatment. The goal was to better understand how the pills work in young people…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated May 07, 2026 18:39 UTC
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Push-Ups with a twist: can blood flow restriction boost explosive power?
Knowledge-focused CompletedThis study tested whether doing push-ups with blood flow restriction (using bands to partially limit blood flow to the arms) can temporarily improve upper body explosive power. Thirty healthy volleyball players aged 18-25 participated. The main goal was to measure how far they co…
Phase: NA • Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC