Istanbul University

This trial tests whether a personalized ventilation strategy, guided by electrical impedance tomography (EIT), can reduce lung complications in men undergoing robot-assisted prostate removal. During this surgery, the abdomen is inflated with gas and the patient is tilted head-dow…

This trial tests whether a 12-week exercise program can improve motor skills, aerobic capacity, and quality of life in children aged 5–13 with autism spectrum disorder. Participants do activities like walking, balancing, and ball games. Researchers compare them to a non-exercisin…

This trial compares two casting strategies for adults with a broken wrist (distal radius fracture) that was set without surgery. One group wears a below-elbow cast from the start, while the other wears an above-elbow cast for two weeks before switching to a below-elbow cast. Rese…

This study looked at whether non-surgical gum disease treatment could reduce inflammation and improve blood fat levels in young adults with severe periodontitis. Fifty participants (25 with gum disease and 25 healthy) were involved. Those with gum disease received deep cleaning a…

This study tested whether combining a knee surgery (microfracture) with an injection of cells from the patient's own fat (SVF) works better than the injection alone for knee osteoarthritis. Fifty people with moderate knee arthritis took part. The researchers measured pain, knee f…

This study aims to translate and test a diagnostic tool called CTS-6 for Turkish-speaking patients with carpal tunnel syndrome. Researchers will enroll 126 adults, including healthy volunteers, people with symptoms, and those already diagnosed. The goal is to ensure the tool is a…

This study tested how well cold, heat, and electric pulp tests detect tooth nerve health in 175 adults needing root canals. Researchers compared test results to direct observation of nerve bleeding during treatment. The goal was to find which test is most accurate for diagnosing …

This study tested whether ultrasound can accurately diagnose mild to moderate carpal tunnel syndrome (CTS) by measuring the median nerve. Researchers compared ultrasound results with standard nerve tests and checked how they related to pain, symptoms, and quality of life in 75 pe…

This study tested a nurse-led home-based fall prevention program for older adults at high risk of falling. The program included health education, specific exercises (Otago exercises), and home safety checks. Researchers measured fall rates, balance, fear of falling, and quality o…

This trial asks whether the Rebozo technique—a traditional method using a woven cloth to gently move the pelvis—can reduce pain and shorten labor in first-time mothers. Around 120 women in active labor will be randomly assigned to receive either the Rebozo technique plus standard…

This trial investigates whether applying a heated pack to the arm for 5 or 10 minutes before inserting a dialysis needle can reduce pain in people with an arteriovenous fistula. About 51 adults on hemodialysis will be randomly assigned to receive heat for 5 minutes, 10 minutes, o…

This trial investigates whether placing a retraction cord—a thin thread that pushes the gum aside—during a tooth restoration affects gum health. Adults with non-carious cervical lesions (tooth damage near the gumline not caused by decay) will receive composite restorations either…

This study tests whether an ultrasound-guided nerve block (erector spinae plane block) can reduce pain and the need for morphine after percutaneous nephrolithotomy, a surgery to remove large kidney stones. Fifty-six adults undergoing elective surgery will be randomly assigned to …

This study tested whether injecting a sugar-water solution (dextrose prolotherapy) into the shoulder can reduce pain and improve function in people with chronic rotator cuff disease. Sixty adults aged 30 to 65 with shoulder pain lasting more than three months took part. The treat…

This study tested whether a cream made from chili pepper extract (capsaicin) or a common pain-relief gel (diclofenac) works better for long-term jaw joint pain. Fifty women with chronic jaw pain applied one of the creams four times a day for a week. Researchers measured pain leve…

This study tests whether adding hip strengthening exercises with resistance bands to regular training can improve jump distance, hip muscle strength, and throwing performance in female handball players aged 15 to 19. Participants do the exercises three times a week for eight week…

This study tests whether giving magnesium during and after spinal surgery can reduce pain and the need for morphine. Adults undergoing multi-level back surgery are randomly assigned to receive either magnesium or a placebo (saline) infusion for 12 hours after surgery. Pain levels…

This study tested whether squeezing a stress ball during an ultrasound-guided biopsy can reduce pain and anxiety. 79 adults were randomly assigned to either use a stress ball or receive standard care alone. Researchers measured pain, anxiety levels, and vital signs before and aft…

This study tested two different ways of preparing Platelet-Rich Plasma (PRP) injections for people with knee osteoarthritis. 96 participants received three injections over six weeks and were followed for six months. The goal was to see which method better reduces pain, improves f…

This study tested whether using a lower amount of fresh gas during anesthesia (low-flow) could reduce lung collapse (atelectasis) after laparoscopic weight-loss surgery. Sixty adults were randomly assigned to receive either low-flow or normal-flow anesthesia. The researchers meas…

This study looked at whether aerobic dance exercises can improve symptoms and quality of life in women with fibromyalgia. Forty-four women were split into two groups: one did aerobic dance sessions led by a physiotherapist, and the other did standard postural exercises. Researche…

This completed study tested whether a nerve block (erector spinae plane block) works better than standard trigger point injections for easing myofascial back pain. 60 adults with myofascial pain syndrome received one of the two procedures. Researchers measured pain levels using a…

This study tested whether showing children a visual guide about the dentist's office could lower their anxiety. 70 kids aged 5 to 14 were split into two groups: one got the picture-based lesson, the other got standard care. The children who saw the pictures reported less fear and…

This study compared two types of nerve blocks—erector spinae plane block and thoracic paravertebral block—for controlling pain after laparoscopic gallbladder removal. 120 adults were randomly assigned to receive one of the blocks or only standard pain medication. The main goal wa…

This study tested whether custom mouthguards (splints) designed using a 3D jaw-tracking device called MODJAW work better than standard mouthguards for people with teeth grinding (bruxism) or jaw pain. 40 adults with mild-to-moderate symptoms wore either a personalized or standard…

This study looked at whether adding postural exercises to standard occlusal splint therapy can better reduce pain and improve jaw function in people with internal temporomandibular joint (TMJ) disorders. Fifty-seven adults were split into three groups: one received only a mouth s…

This study compared a special hand therapy (mCIMT) delivered via video calls to a standard home program in 42 children with unilateral cerebral palsy. The therapy group did one-hour sessions three times a week for six weeks, plus daily activities. The goal was to see if telerehab…

This study tests whether adding innovation workshops to a project-planning course helps nursing students think more critically and creatively. About 50 third-year students will take the special course or a standard elective, and researchers will measure changes in their motivatio…

This study looked at immune cells (T and B cells) in the blood of 44 people with a kidney disease called membranous nephropathy. Researchers wanted to see how these cells relate to treatment response and disease relapse. They also measured specific antibodies linked to the diseas…

This study looked at whether a tool called the Surgical Pleth Index (SPI), which measures stress during surgery, can predict how much pain a person will feel after waking up from a brain operation. 52 adults having craniotomy were monitored, and their pain scores and painkiller u…

This study tested whether a Spanish pressure injury risk scale, called EVARUCI, works well in Turkish intensive care units. Researchers translated it and checked its accuracy in 100 adult ICU patients without existing bedsores. The goal was to give nurses a reliable way to spot p…

This study surveyed 190 intensive care unit nurses worldwide to find out what they know and think about eye care for their patients. The goal was to see if nurses follow the latest guidelines for preventing eye problems in critically ill patients. The results help identify gaps i…

This study looked at whether people on hemodialysis know how to safely disconnect themselves from the dialysis machine during an emergency, like a fire or power outage. Researchers tested 620 patients from multiple countries using a checklist. The goal was to see if patients coul…

This study looked at how different oxygen levels during laparoscopic lower abdominal surgery affect stress markers in the lungs and blood. 76 adults were randomly assigned to receive either normal (35%) or high (80%) oxygen during surgery. Researchers measured changes in various …

This pilot study explored whether people with Friedreich's ataxia (FA) have problems making certain hormones, like cortisol and testosterone. Researchers measured hormone levels in blood samples from 11 FA patients and 15 healthy volunteers. The goal was to better understand how …

This study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that using more wires was linked to a higher chance of deep infections and prolonged wound drainage. The fi…

This study looked at whether a blood marker called PTX3 can predict how well people do after gastric bypass surgery. Researchers followed 23 patients for 6 months after surgery, measuring weight loss, insulin resistance, and inflammation. The goal was to see if PTX3 levels before…

This study tested whether doing push-ups with a cuff that partially restricts blood flow to the arms can improve upper body explosive power in volleyball players. Thirty healthy athletes aged 18-25 completed the trial. The goal was to see if this technique, called blood flow rest…

This completed study looked at jawbone X-rays from 120 people—half with gum disease and half healthy. Researchers used special computer analysis to measure bone structure differences. The goal was to see if routine dental X-rays could help detect early bone changes caused by peri…

This completed study from Istanbul University looked at 64 obese adults to see if obesity hypoventilation syndrome (OHS) causes extra problems beyond obesity alone. Researchers measured exercise capacity, muscle strength, sleep quality, and quality of life. The goal was to unders…

This study tested four different methods of pushing back the gums (gingival retraction) to see which one gives the best digital dental scan. Fifty healthy adults with good oral hygiene took part. The goal was to find the method that balances clear scans, patient comfort, and mini…

This study measured steroid hormone levels in 56 adolescents and young women with PCOS before and after 6 months of oral contraceptive treatment. Researchers used a precise lab method to track changes in hormones like testosterone. The goal was to better understand how birth cont…