Fat cell therapy shows promise for knee arthritis

NCT ID NCT07112885

Completed Disease control Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether combining a knee surgery (microfracture) with an injection of cells from the patient's own fat (SVF) works better than the injection alone for knee osteoarthritis. Fifty people with moderate knee arthritis took part. The researchers measured pain, knee function, and cartilage changes using MRI over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stromal vascular fraction (SVF) from the patient's own fat tissue
What this could lead to: If successful, this combination could offer a better way to reduce pain and improve knee function in people with knee osteoarthritis.
What could go wrong: This is a small, early-stage trial with only 50 participants. The results may not apply to everyone, and the long-term benefits or risks are still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fractures, Stress osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS (KNEE OA)

Contacts and locations

Locations

Istanbul University Faculty of Medicine

Istanbul, 34320, Turkey (Türkiye)

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